State MO
Clinical Trials in Missouri
Missouri is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Missouri and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 288 actively recruiting studies with Missouri sites out of 288 registered in total. The busiest research areas in Missouri are Obesity, Breast Cancer, Overweight. Leading sponsors running trials in the state include Washington University School of Medicine, National Cancer Institute (NCI), Merck Sharp & Dohme LLC. By stage, Missouri trials break down as Phase 1 (49), Phase 2 (87), Phase 3 (95), Phase 4 (11).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Missouri
Frequently Asked Questions — Clinical Trials in Missouri
How many clinical trials are currently recruiting in Missouri?
ClinicalMetric currently tracks 288 actively recruiting clinical trials with at least one location in Missouri. The total number of registered studies—including active but not currently enrolling trials—is 288. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Missouri?
Missouri hosts clinical trials across a broad range of medical conditions, including Obesity, Breast Cancer, Overweight, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Missouri serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Missouri?
To join a clinical trial in Missouri, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Missouri maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Missouri
NCT05150691 Phase 1, Phase 2
Recruiting
A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors
Condition
HER2-positive Advanced Solid Tumor
Enrollment
796 pts
Location
United States, Australia, China
Sponsor
DualityBio Inc.
NCT05104710 N/A
Recruiting
Intermuscular Coherence as a Biomarker for ALS
Condition
Amyotrophic Lateral Sclerosis
Enrollment
650 pts
Location
United States
Sponsor
University of Chicago
NCT05667142 Phase 3
Recruiting
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-C...
Condition
Primary Generalized Tonic-Clonic Seizures
Enrollment
160 pts
Location
United States, Argentina, Australia
Sponsor
Xenon Pharmaceuticals Inc.
NCT07867080 Phase 3
Recruiting
A Phase 3 Trial for Intravitreal Injection of 4D-150 in Adults With Diabetic Mac...
Condition
Diabetic Macular Edema (DME)
Enrollment
514 pts
Location
United States, China, Japan
Sponsor
4D Molecular Therapeutics
NCT02432560 N/A
Recruiting
Safety and Durability of Sirolimus for Treatment of LAM
Condition
Lymphangioleiomyomatosis
Enrollment
600 pts
Location
United States
Sponsor
University of Cincinnati
NCT06960213 Phase 3
Recruiting
STOP-HAE: A Phase 3 Study of ADX-324 in HAE
Condition
Hereditary Angioedema
Enrollment
90 pts
Location
United States, Argentina, Australia
Sponsor
ADARx Pharmaceuticals, Inc.
NCT00567073 N/A
Recruiting
Pompe Pregnancy Sub-Registry
Condition
Glycogen Storage Disease Type II (GSD-II)
Enrollment
20 pts
Location
United States, Australia, Belgium
Sponsor
Genzyme, a Sanofi Company
NCT03999983 N/A
Recruiting
Vertebral Artery Origin Treatment Via Endovascular Techniques Registry (VOTER)
Condition
Vertebral Artery Stenosis
Enrollment
150 pts
Location
United States
Sponsor
St. Louis University
NCT07243652 N/A
Recruiting
I-DECIDE After Bronchiolitis Hospitalization
Condition
Bronchiolitis Acute
Enrollment
2,700 pts
Location
United States, Canada
Sponsor
Seattle Children's Hospital
NCT04715178 N/A
Recruiting
Beat Childhood Cancer Specimen Banking and Data Registry
Condition
Pediatric Cancer
Enrollment
1,000 pts
Location
United States
Sponsor
Giselle Sholler
NCT07115017 N/A
Recruiting
This Study Involves a Positron Emission Tomography (PET) Scan Using a New Invest...
Condition
Multiple Sclerosis
Enrollment
80 pts
Location
United States
Sponsor
Washington University School o
NCT07428538 Phase 3
Recruiting
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With ...
Condition
Hepatitis
Enrollment
350 pts
Location
United States
Sponsor
Bausch Health Americas, Inc.
NCT07177417 Phase 4
Recruiting
Characterizing the Human Airway Immune Response to FluMist Vaccination
Condition
Healthy Young Adults
Enrollment
30 pts
Location
United States
Sponsor
Washington University School o
NCT07221474 Phase 2
Recruiting
A Study of Intismeran Autogene (V940)/Placebo + Pembrolizumab and Chemotherapy i...
Condition
Squamous Non-small Cell Lung Cancer
Enrollment
180 pts
Location
United States, Argentina, Australia
Sponsor
Merck Sharp & Dohme LLC
NCT05110989 N/A
Recruiting
A Multicenter Patient Registry on Outcomes From Cryoanalgesia of the Intercostal...
Condition
Post Operative Pain
Enrollment
5,000 pts
Location
United States, Austria, Belgium
Sponsor
AtriCure, Inc.
NCT06906367 N/A
Recruiting
A Study of Patients With Fabry Disease (US Specific)
Condition
Fabry Disease
Enrollment
450 pts
Location
United States
Sponsor
Amicus Therapeutics
NCT07845487 Phase 2
Recruiting
A Trial to Investigate PALI-2108 Versus Placebo in Participants With Moderately ...
Condition
Ulcerative Colitis (UC)
Enrollment
204 pts
Location
United States, Canada, Czechia
Sponsor
Palisade Bio
NCT06636149 N/A
Recruiting
Maternal Maneuvers During Prolonged Labor
Condition
Labor Stage, First
Enrollment
82 pts
Location
United States
Sponsor
Washington University School o
NCT06925321 Phase 3
Recruiting
A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult P...
Condition
Invasive Mold Infections
Enrollment
234 pts
Location
United States, Australia, Austria
Sponsor
Basilea Pharmaceutica
NCT06783309 Phase 1, Phase 2
Recruiting
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Wit...
Condition
Type 1 Diabetes Mellitus
Enrollment
72 pts
Location
United States
Sponsor
COUR Pharmaceutical Developmen
NCT07347106 N/A
Recruiting
Miro3D Randomized Controlled Trial (RCT)
Condition
Wound
Enrollment
70 pts
Location
United States
Sponsor
Washington University School o
NCT06597006 Phase 3
Recruiting
Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children Wi...
Condition
Familial Hypercholesterolemia - Homozygous
Enrollment
9 pts
Location
United States, Austria, China
Sponsor
Novartis Pharmaceuticals
NCT06401421 N/A
Recruiting
EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Brea...
Condition
Breast Cancer
Enrollment
1,800 pts
Location
United States, Canada
Sponsor
Exact Sciences Corporation
NCT07132307 N/A
Recruiting
Reducing Obstructive Sleep Apnea After Hypoglossal Nerve Stimulation Through Man...
Condition
Obstructive Sleep Apnea
Enrollment
30 pts
Location
United States
Sponsor
Washington University School o
NCT05267821 Phase 2, Phase 3
Recruiting
Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS
Condition
Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)
Enrollment
500 pts
Location
United States
Sponsor
Nationwide Children's Hospital
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology