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advanced solid tumor

Total Trials
46
Recruiting Now
46
Trial Phases
Phase 1, Phase 2, Phase 1, Phase 2

ClinicalMetric tracks all active clinical trials for advanced solid tumor sourced from ClinicalTrials.gov. Each listing includes the NCT identifier, current recruitment status, phase, primary endpoints, sponsor, estimated enrollment, and participating countries — updated daily as new studies open and status changes.

  • Recruiting trials currently enrolling participants, with eligibility criteria and age requirements
  • Phase 1–4 studies from early safety trials to post-marketing surveillance
  • NIH, pharmaceutical sponsor, and academic medical center studies worldwide
  • AI-powered plain-language summary available for every trial listing

Frequently Asked Questions — advanced solid tumor Clinical Trials

How many clinical trials are currently recruiting for advanced solid tumor?
ClinicalMetric currently tracks 46 actively recruiting clinical trials for advanced solid tumor, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 46. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for advanced solid tumor?
advanced solid tumor research spans Phase 1 (44 trials), Phase 2 (18 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a advanced solid tumor clinical trial?
Eligibility criteria for advanced solid tumor trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
44
Phase 2
18
Top Sponsors
Daiichi Sankyo 2 trials
Jiangsu Hansoh Pharmaceutical Co., Ltd. 1 trial
Novartis Pharmaceuticals 1 trial
MonTa Biosciences ApS 1 trial
Broadenbio Ltd., Co. 1 trial

Recruiting Clinical Trials

NCT05367778 Phase 1, Phase 2
Recruiting

Phase 1/2 Study of HS-10370 in Patients with Advanced Solid Tumors

Enrollment
176 pts
Location
China
Sponsor
Jiangsu Hansoh Pharmaceutical ...
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NCT04104776 Phase 1, Phase 2
Recruiting

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

Enrollment
275 pts
Location
United States, Franc...
Sponsor
Novartis Pharmaceuticals
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NCT04855435 Phase 1
Recruiting

Safety and Preliminary Efficacy of MBS8(1V270) in Cancer Patients With Advanced Solid Tumours

Enrollment
106 pts
Location
Denmark, Spain
Sponsor
MonTa Biosciences ApS
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NCT06258408 Phase 1
Recruiting

A Phase 1 Study of BB102 in Participants With Advanced Solid Tumors

Enrollment
78 pts
Location
China
Sponsor
Broadenbio Ltd., Co.
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NCT06108050 Phase 1
Recruiting

JZP898 Intravenous Infusion as Monotherapy and Combination With Pembrolizumab in Adults With Advanced/Metastatic Solid Tumors

Enrollment
177 pts
Location
United States
Sponsor
Jazz Pharmaceuticals
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NCT05772455 Phase 1
Recruiting

A Study of XZB-0004 in Patients With Solid Tumors

Enrollment
128 pts
Location
China
Sponsor
Xuanzhu Biopharmaceutical Co.,...
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NCT05836948 Phase 1
Recruiting

The Clinical Study of SHR-9839 for Injection in Patients With Advanced Solid Tumors

Enrollment
174 pts
Location
China
Sponsor
Shanghai Hengrui Pharmaceutica...
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NCT07098299 Phase 1
Recruiting

Metformin Combined With Chemotherapy and/or Immunotherapy in Solid Malignancies

Enrollment
60 pts
Location
United States
Sponsor
Barbara Ann Karmanos Cancer In...
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NCT05867251 Phase 1, Phase 2
Recruiting

Study of AVZO-021 in Patients With Advanced Solid Tumors

Enrollment
430 pts
Location
United States, Austr...
Sponsor
Avenzo Therapeutics, Inc.
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NCT06223256 Phase 1
Recruiting

A Study of NBL-028 in Patients With Advanced Solid Tumors

Enrollment
270 pts
Location
China
Sponsor
NovaRock Biotherapeutics, Ltd
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NCT06170294 Phase 1
Recruiting

MAGE-A4-directed TCR-T in the Treatment Amongst Subjects With Advanced Solid Tumors

Enrollment
20 pts
Location
China
Sponsor
Peking University
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NCT06171750 Phase 1
Recruiting

Phase I Study of Tolododekin Alfa (ANK-101) in Advanced Solid Tumors

Enrollment
97 pts
Location
United States, Canad...
Sponsor
Ankyra Therapeutics, Inc
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NCT06362369 Phase 1, Phase 2
Recruiting

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

Enrollment
126 pts
Location
United States
Sponsor
7 Hills Pharma, LLC
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NCT05279300 Phase 1
Recruiting

A Study of CS5001 in Patients With Advanced Solid Tumors and Lymphomas

Enrollment
480 pts
Location
United States, Austr...
Sponsor
CStone Pharmaceuticals
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NCT05877430 Phase 1, Phase 2
Recruiting

Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer

Enrollment
160 pts
Location
United States, South...
Sponsor
CJ Bioscience, Inc.
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NCT04827810 Phase 1
Recruiting

A Phase I Safety and Pharmacokinetic Study of Gamitrinib Administered Intravenously to Patients With Advanced Cancer

Enrollment
42 pts
Location
United States
Sponsor
Fox Chase Cancer Center
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NCT04145622 Phase 1, Phase 2
Recruiting

Study of Ifinatamab Deruxtecan (DS-7300a, I-DXd) in Participants With Advanced Solid Malignant Tumors

Enrollment
250 pts
Location
United States, Japan
Sponsor
Daiichi Sankyo
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NCT05875168 Phase 1, Phase 2
Recruiting

First-in-Human Study of DS-3939a in Participants With Advanced Solid Tumors

Enrollment
540 pts
Location
United States, Belgi...
Sponsor
Daiichi Sankyo
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NCT05892718 Phase 1
Recruiting

A Safety and Efficacy Study of HCB101, Fc-fusion Protein Targeting SIRPα-CD47 Pathway, in Solid or Hematological Tumors

Enrollment
80 pts
Location
United States, China...
Sponsor
FBD Biologics Limited
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NCT05269316 Phase 1, Phase 2
Recruiting

Study to Evaluate IMP9064 as a Monotherapy or in Combination in Patients With Advanced Solid Tumors

Enrollment
61 pts
Location
United States, Austr...
Sponsor
Impact Therapeutics, Inc.
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NCT06833008 Phase 1, Phase 2
Recruiting

A Study to Assess a New Medicine Called IPN01195 When Administered Alone in Adults With Advanced Solid Tumours

Enrollment
85 pts
Location
United States, Franc...
Sponsor
Ipsen
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NCT06404905 Phase 1
Recruiting

Clinical Trial of BT02 in Patients With Advanced Solid Tumors

Enrollment
60 pts
Location
China
Sponsor
Cancer Institute and Hospital,...
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NCT06514651 Phase 1
Recruiting

MAQ-001 in Patients With Advanced Solid Tumors

Enrollment
30 pts
Location
France
Sponsor
MabQuest SA
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NCT06974110 Phase 1
Recruiting

Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors

Enrollment
132 pts
Location
United States, Austr...
Sponsor
MOMA Therapeutics
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NCT05725291 Phase 1
Recruiting

AMT-116 in Patients With Advanced Solid Tumors

Enrollment
80 pts
Location
United States, Ameri...
Sponsor
Multitude Therapeutics Inc.
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NCT06463340 Phase 1
Recruiting

Study of SGR-3515 In Participants With Advanced Solid Tumors.

Enrollment
52 pts
Location
United States, Canad...
Sponsor
Schrödinger, Inc.
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NCT05263960 Phase 1, Phase 2
Recruiting

A Study of CM350 in Patients With Advanced Solid Tumors

Enrollment
248 pts
Location
China
Sponsor
Keymed Biosciences Co.Ltd
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NCT05687682 Phase 1
Recruiting

Safety of AM-928 Infusion in Advanced Solid Tumors

Enrollment
38 pts
Location
Taiwan
Sponsor
AcadeMab Biomedical Inc.
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NCT06484816 Phase 1
Recruiting

TGRX-1942 Chinese Phase I for Advanced Solid Tumor And/or Relapsed/Refractory Hematologic Malignancies

Enrollment
90 pts
Location
China
Sponsor
Shenzhen TargetRx Co., Ltd.
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NCT07070232 Phase 1, Phase 2
Recruiting

A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors

Enrollment
980 pts
Location
United States, Austr...
Sponsor
BioNTech SE
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NCT05098132 Phase 1, Phase 2
Recruiting

Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers

Enrollment
364 pts
Location
United States
Sponsor
Synthekine
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NCT06635785 Phase 1, Phase 2
Recruiting

Safety, Pharmacokinetics, and Efficacy of AI-081, a Bispecific Antibody for PD-1 And VEGF in Advanced Solid Tumors

Enrollment
387 pts
Location
United States
Sponsor
OncoC4, Inc.
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NCT05979155 Phase 1
Recruiting

A Study of NWY001 in Subjects With Advanced Solid Tumors

Enrollment
196 pts
Location
China
Sponsor
Chipscreen Biosciences, Ltd.
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NCT05204862 Phase 1, Phase 2
Recruiting

Phase 1/2 Study of TU2218 Alone and in Combination With Checkpoint Inhibitors in Patients With Advanced Solid Tumors

Enrollment
240 pts
Location
United States, South...
Sponsor
TiumBio Co., Ltd.
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NCT04762641 Phase 1
Recruiting

This is a Study to Evaluate the Safety and Tolerability of ABL503, and to Determine the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D) of ABL503 in Subjects with Any Progressive Locally Advanced or Metastatic Solid Tumors

Enrollment
100 pts
Location
United States, South...
Sponsor
ABL Bio, Inc.
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NCT06251310 Phase 1
Recruiting

SW-682 in Advanced Solid Tumors

Enrollment
186 pts
Location
United States
Sponsor
SpringWorks Therapeutics, Inc....
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NCT06090266 Phase 1, Phase 2
Recruiting

A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents

Enrollment
168 pts
Location
United States
Sponsor
OncoResponse, Inc.
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NCT04510766
Recruiting

Tumor Molecular Profiling in Early Phase Clinical Trials

Enrollment
40 pts
Location
Switzerland
Sponsor
Oncology Institute of Southern...
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NCT05898399 Phase 1, Phase 2
Recruiting

Study of ART6043 in Advanced/Metastatic Solid Tumors Patients (POLKA)

Enrollment
181 pts
Location
United States, Spain
Sponsor
Artios Pharma Ltd
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NCT04890613 Phase 1
Recruiting

Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation

Enrollment
52 pts
Location
United States, Canad...
Sponsor
Senhwa Biosciences, Inc.
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NCT06566079 Phase 1
Recruiting

Study of ISM6331 in Participants With Advanced/Metastatic Malignant Mesothelioma or Other Solid Tumors

Enrollment
100 pts
Location
United States, China
Sponsor
InSilico Medicine Hong Kong Li...
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NCT05142423 Phase 1, Phase 2
Recruiting

A Study of AK109 Combined With AK104 in Patients With Advanced Solid Tumors

Enrollment
198 pts
Location
China
Sponsor
Akeso
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NCT03767075 Phase 2
Recruiting

A Modular Multi-Basket Trial to Improve Personalized Medicine in Cancer Patients (Basket of Baskets)

Enrollment
1,000 pts
Location
France, Germany, Ita...
Sponsor
Vall d'Hebron Institute of Onc...
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NCT07166601 Phase 1
Recruiting

M0324 as Monotherapy and in Combination With Pembrolizumab or Chemotherapy in Participants With Selected Advanced Solid Tumors

Enrollment
77 pts
Location
United States, Canad...
Sponsor
EMD Serono Research & Developm...
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NCT06120283 Phase 1
Recruiting

BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors

Enrollment
399 pts
Location
United States, Austr...
Sponsor
BeOne Medicines
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NCT05143970 Phase 1
Recruiting

A Phase 1 First-In-Human Study of the Anti-CD73 IPH5301 Alone or in Combination With Chemotherapy and Trastuzumab in Patients With Advanced Solid Tumors

Enrollment
27 pts
Location
France
Sponsor
Institut Paoli-Calmettes
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology