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Medical Condition

advanced solid tumor

Total Trials
40
Recruiting Now
40
Trial Phases
Phase 1, Phase 2, Phase 1, Phase 2
NCT06533059 Phase 1
Recruiting

A Study to Learn About Study Medicine ALTA2618 in Adults With AKT1 E17K-Mutant Solid Tumors

Enrollment
110 pts
Location
United States, Austr...
Sponsor
Alterome Therapeutics, Inc.
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NCT07269080 Phase 1
Recruiting

STM-06: POLARIS-POlymetastic Lesion Ablative Radiotherapy With Immunotherapy Study

Enrollment
28 pts
Location
United States
Sponsor
University of Illinois at Chic...
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NCT03767075 Phase 2
Recruiting

A Modular Multi-Basket Trial to Improve Personalized Medicine in Cancer Patients (Basket of Baskets)

Enrollment
1,000 pts
Location
France, Germany, Ita...
Sponsor
Vall d'Hebron Institute of Onc...
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NCT06163391 Phase 1
Recruiting

A Study to Assess Safety and Efficacy of SOT201 in Patients With Advanced/Metastatic Cancer

Enrollment
40 pts
Location
United States, Belgi...
Sponsor
SOTIO Biotech AG
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NCT07284186 Phase 1
Recruiting

First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

Enrollment
155 pts
Location
United States
Sponsor
Plexium, Inc.
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NCT07260591 Phase 1
Recruiting

VSV-02 Compassionate Use in Advanced Solid Tumors

Enrollment
6 pts
Location
China
Sponsor
The First Affiliated Hospital ...
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NCT05983523 Phase 1
Recruiting

A Study of PEP07 (Checkpoint Kinase 1 Inhibitor) in Patients with Advanced or Metastatic Solid Tumors

Enrollment
54 pts
Location
Taiwan
Sponsor
PharmaEngine
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NCT06233942 Phase 1
Recruiting

Phase 1a/1b First-in-Human Study of BG-C9074 Alone and in Combination With Other Anticancer Therapies in Patients With Advanced Solid Tumors

Enrollment
308 pts
Location
United States, Austr...
Sponsor
BeOne Medicines
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NCT06997029 Phase 1
Recruiting

A Phase 1 Study of BMS-986500 as Monotherapy or Combination Therapy in Advanced Solid Tumors

Enrollment
234 pts
Location
United States, Denma...
Sponsor
Bristol-Myers Squibb
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NCT06139211 Phase 1, Phase 2
Recruiting

A Phase Ib/II Study Of JS015 Combination Therapy in Advanced Solid Tumors

Enrollment
186 pts
Location
China
Sponsor
Shanghai Junshi Bioscience Co....
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NCT06587295 Phase 1
Recruiting

Intramuscular ACM-CpG Monotherapy in Patients With Advanced/Metastatic Solid Tumors With Prior Response to Immunotherapy Alone or in Combination With Chemotherapy

Enrollment
40 pts
Location
Singapore
Sponsor
National Cancer Centre, Singap...
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NCT06130254 Phase 1
Recruiting

Phase Ib Trial of the KRAS G12C Inhibitor Adagrasib (MRTX849) in Combination With the PARP Inhibitor Olaparib in Patients With KRAS G12C Mutated Advanced Solid Tumors, With a Focus on Gynecological, Breast, Pancreatic and KEAP1 Mutated Non-small Cell Lung Cancers

Enrollment
52 pts
Location
United States
Sponsor
M.D. Anderson Cancer Center
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NCT06251310 Phase 1
Recruiting

SW-682 in Advanced Solid Tumors

Enrollment
186 pts
Location
United States
Sponsor
SpringWorks Therapeutics, Inc.
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NCT06938880 Phase 1, Phase 2
Recruiting

Study of ZGGS18 in Combination With ZG005 in Patients With Advanced Solid Tumors

Enrollment
60 pts
Location
China
Sponsor
Suzhou Zelgen Biopharmaceutica...
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NCT04390737 Phase 1, Phase 2
Recruiting

Evaluate the Safety and Clinical Activity of HH2853

Enrollment
254 pts
Location
United States, China
Sponsor
Haihe Biopharma Co., Ltd.
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NCT04510766
Recruiting

Tumor Molecular Profiling in Early Phase Clinical Trials

Enrollment
40 pts
Location
Switzerland
Sponsor
Oncology Institute of Southern...
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NCT05768932 Phase 1
Recruiting

BAL0891 in Patients With Advanced Solid Tumors or Relapsed or Refractory Acute Myeloid Leukemia

Enrollment
260 pts
Location
United States, South...
Sponsor
SillaJen, Inc.
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NCT06408688 Phase 4
Recruiting

Safety and Modulation of Adaptive Immunity by Iscador® Qu Viscum Album Extract in Patients With Advanced, Recurrent or Metastatic Cancers Treated With Immune Checkpoint Inhibitors

Enrollment
100 pts
Location
Switzerland
Sponsor
University Hospital, Basel, Sw...
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NCT06247657 Phase 1
Recruiting

A Phase I Study to Assess the Safety and Tolerability of BL0006 for Patients With Advanced Solid Tumours

Enrollment
66 pts
Location
China
Sponsor
Shanghai Best-Link Bioscience,...
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NCT06682780 Phase 1, Phase 2
Recruiting

A Phase I/II Study of LM-2417 in Subjects With Advanced Solid Tumours

Enrollment
320 pts
Location
China
Sponsor
LaNova Medicines Limited
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NCT07083323 Phase 1, Phase 2
Recruiting

A Phase I/II Study of HY05350 in Mesothelin(MSLN)-Positive Advanced Solid Tumors

Enrollment
262 pts
Location
China
Sponsor
Sichuan Huiyu Pharmaceutical C...
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NCT05875168 Phase 1, Phase 2
Recruiting

First-in-Human Study of DS-3939a in Participants With Advanced Solid Tumors

Enrollment
540 pts
Location
United States, Belgi...
Sponsor
Daiichi Sankyo
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NCT06887348
Recruiting

A Study to Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP3

Enrollment
50 pts
Location
United States, Austr...
Sponsor
Replimune Inc.
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NCT05038150 Phase 1, Phase 2
Recruiting

Study of SGN1 in Patients With Advanced Solid Tumor

Enrollment
70 pts
Location
United States, China
Sponsor
Guangzhou Sinogen Pharmaceutic...
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NCT06132503 Phase 1
Recruiting

Safety, Pharmacokinetics, and Clinical Activity of LP-284 in Adult Patients With Relapsed or Refractory Lymphomas and Solid Tumors

Enrollment
110 pts
Location
United States
Sponsor
Lantern Pharma Inc.
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NCT05329103 Phase 1
Recruiting

A Study to Evaluate PEEL-224 in Patients With Advanced Solid Tumors

Enrollment
65 pts
Location
United States
Sponsor
Peel Therapeutics Inc
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NCT05661461 Phase 1
Recruiting

Dose-escalation Study to Assess Safety and Pharmacokinetics of Nab-Sirolimus in Patients With Locally Advanced or Metastatic Solid Tumors and Moderate Liver Impairment

Enrollment
28 pts
Location
United States
Sponsor
Aadi Bioscience, Inc.
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NCT06660654 Phase 2
Recruiting

A Study of Raludotatug Deruxtecan in Participants With Advanced/Metastatic Solid Tumors (REJOICE-PanTumor01)

Enrollment
200 pts
Location
United States, Belgi...
Sponsor
Daiichi Sankyo
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NCT06577194 Phase 2
Recruiting

A Single-Center, Single-Arm Study of Neoadjuvant Short-Course Radiotherapy With IL-2 Followed by Sequential Immunotherapy With CAPOX Combined With PD-1 Antibody and IL-2 for Locally Advanced Rectal Cancer

Enrollment
35 pts
Location
China
Sponsor
The First Affiliated Hospital ...
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NCT06173219 Phase 1, Phase 2
Recruiting

Safety and Efficacy of Radiotherapy Combined with Immunotherapy for Advanced Malignant Tumors.

Enrollment
38 pts
Location
China
Sponsor
China-Japan Friendship Hospita...
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NCT06170294 Phase 1
Recruiting

MAGE-A4-directed TCR-T in the Treatment Amongst Subjects With Advanced Solid Tumors

Enrollment
20 pts
Location
China
Sponsor
Peking University
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NCT05819684 Phase 1
Recruiting

A Study of SHR-4602 in Subjects With Advanced Malignant Solid Tumors

Enrollment
133 pts
Location
China
Sponsor
Suzhou Suncadia Biopharmaceuti...
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NCT06973863 Phase 1
Recruiting

A Study of PEP08 in Patients With MTAP-Del Advanced or Metastatic Solid Tumors

Enrollment
40 pts
Location
Australia, Taiwan
Sponsor
PharmaEngine
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NCT06258408 Phase 1
Recruiting

A Phase 1 Study of BB102 in Participants With Advanced Solid Tumors

Enrollment
78 pts
Location
China
Sponsor
Broadenbio Ltd., Co.
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NCT06463340 Phase 1
Recruiting

Study of SGR-3515 In Participants With Advanced Solid Tumors.

Enrollment
52 pts
Location
United States, Canad...
Sponsor
Schrödinger, Inc.
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NCT04585750 Phase 1, Phase 2
Recruiting

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Enrollment
300 pts
Location
United States, Austr...
Sponsor
PMV Pharmaceuticals, Inc
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NCT05873686 Phase 1
Recruiting

A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers

Enrollment
140 pts
Location
United States, Unite...
Sponsor
Nuvectis Pharma, Inc.
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NCT05269316 Phase 1, Phase 2
Recruiting

Study to Evaluate IMP9064 as a Monotherapy or in Combination in Patients With Advanced Solid Tumors

Enrollment
61 pts
Location
United States, Austr...
Sponsor
Impact Therapeutics, Inc.
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NCT06154291 Phase 1, Phase 2
Recruiting

FIH XON7 in Advanced/Metastatic Solid Tumors

Enrollment
255 pts
Location
Belgium, France
Sponsor
Xenothera SAS
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NCT04890613 Phase 1
Recruiting

Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation

Enrollment
52 pts
Location
United States, Canad...
Sponsor
Senhwa Biosciences, Inc.
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