Medical Condition

major depressive disorder

Total Trials

21

Recruiting Now

21

Trial Phases

Phase 4, Phase 2, Phase 3

ClinicalMetric tracks all active clinical trials for major depressive disorder sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — major depressive disorder Clinical Trials

How many clinical trials are currently recruiting for major depressive disorder?

ClinicalMetric currently tracks 21 actively recruiting clinical trials for major depressive disorder, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 21. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for major depressive disorder?

major depressive disorder research spans Phase 2 (8 trials), Phase 3 (2 trials), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a major depressive disorder clinical trial?

Eligibility criteria for major depressive disorder trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 2

Phase 3

Phase 4

Top Sponsors

Mclean Hospital 2 trials

Icahn School of Medicine at Mount Sinai 2 trials

Neurocrine Biosciences 1 trial

Baylor College of Medicine 1 trial

University Hospital Tuebingen 1 trial

major depressive disorder

Frequently Asked Questions — major depressive disorder Clinical Trials

Recruiting Clinical Trials

Related Conditions