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Medical Condition

major depressive disorder

Total Trials
27
Recruiting Now
27
Trial Phases
Phase 2, Phase 3, Phase 2, Phase 3
NCT05809609
Recruiting

Glutamate Emotion Memory Study

Enrollment
60 pts
Location
United Kingdom
Sponsor
University of Oxford
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NCT06529029 Phase 2, Phase 3
Recruiting

Low Amplitude Pulse Seizure Therapy Versus Standard Ultra-Brief Right Unilateral Electroconvulsive Therapy

Enrollment
30 pts
Location
United States
Sponsor
Michigan State University
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NCT04637620 Phase 2
Recruiting

NMDA Modulation in Major Depressive Disorder

Enrollment
90 pts
Location
Taiwan
Sponsor
China Medical University Hospi...
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NCT04041479 Phase 3
Recruiting

Biomarker-guided rTMS for Treatment Resistant Depression

Enrollment
348 pts
Location
United States
Sponsor
Weill Medical College of Corne...
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NCT07276997 Phase 2
Recruiting

A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive Disorder

Enrollment
195 pts
Location
United States
Sponsor
AbbVie
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NCT05384405
Recruiting

aiTBS for Relieving NSSI in Depressive Patients

Enrollment
60 pts
Location
China
Sponsor
Central South University
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NCT05239780
Recruiting

Invasive Decoding and Stimulation of Altered Reward Computations in Depression Patients

Enrollment
10 pts
Location
United States
Sponsor
Icahn School of Medicine at Mo...
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NCT06110897
Recruiting

RESISTance Exercise for Depression Trial

Enrollment
200 pts
Location
United States
Sponsor
University of Wisconsin, Madis...
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NCT06860724
Recruiting

Linking Affective Dynamics in Response to Daily Stress to Peripheral Vascular Function in Working Age Adults

Enrollment
18 pts
Location
United States
Sponsor
University of Delaware
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NCT05357040 Phase 2
Recruiting

Antidepressant Effects of Nitrous Oxide

Enrollment
172 pts
Location
United States, Austr...
Sponsor
University of Chicago
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NCT03665831
Recruiting

Deep TMS for Comorbid Depression and Cognitive Impairment in Older Adults

Enrollment
28 pts
Location
Canada
Sponsor
Rotman Research Institute at B...
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NCT07305701
Recruiting

Cohort Study on Medical Students' Mental Health

Enrollment
10,000 pts
Location
France
Sponsor
Centre Hospitalier Régional d'...
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NCT06050070
Recruiting

Targeting Large-scale Networks in Depression With Real-time Functional Magnetic Resonance Imaging (fMRI) Neurofeedback

Enrollment
70 pts
Location
United States
Sponsor
University of Michigan
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NCT06968390
Recruiting

Accelerated TMS for Perinatal Depression

Enrollment
24 pts
Location
United States
Sponsor
Brigham and Women's Hospital
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NCT06086366
Recruiting

Presynaptic Imaging in Major Depressive Episodes After COVID-19

Enrollment
90 pts
Location
Canada
Sponsor
Centre for Addiction and Menta...
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NCT05547035
Recruiting

Identification of Physiological Data by a Wearable Monitor in Subjects Suffering From Major Depression Disorders

Enrollment
200 pts
Location
France
Sponsor
Digital For Mental Health
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NCT04685148 Phase 1, Phase 2
Recruiting

Maternal Mental Health Trial

Enrollment
220 pts
Location
Denmark
Sponsor
Vibe G Frøkjær, MD, PhD
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NCT05913960
Recruiting

Accelerated Intermittent Theta-Burst Stimulation Ameliorate Major Depressive Disorder by Regulating CAMKII Pathway

Enrollment
90 pts
Location
China
Sponsor
First Affiliated Hospital of Z...
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NCT04751331 Phase 1, Phase 2
Recruiting

Neural Response to Inflammatory Challenge in Major Depressive Disorder

Enrollment
180 pts
Location
United States
Sponsor
Laureate Institute for Brain R...
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NCT06058039 Phase 3
Recruiting

Study to Assess the Effects of Oral NMRA-335140 in Participants With Major Depressive Disorder

Enrollment
332 pts
Location
United States, Bulga...
Sponsor
Neumora Therapeutics, Inc.
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NCT03437928
Recruiting

DBS for Depression

Enrollment
12 pts
Location
United States
Sponsor
Baylor College of Medicine
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NCT06350396
Recruiting

pBFS-guided rTMS Over DMPFC for Treatment-Resistant Depression

Enrollment
270 pts
Location
China
Sponsor
Changping Laboratory
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NCT07204314 Phase 3
Recruiting

A Study of Vortioxetine in Japanese Pediatric Patients With Major Depressive Disorder

Enrollment
180 pts
Location
Japan
Sponsor
Takeda
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NCT06547489 Phase 2
Recruiting

Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

Enrollment
164 pts
Location
United States
Sponsor
Syndeio Biosciences, Inc
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NCT03748446 EARLY_Phase 1
Recruiting

Xenon Inhalation Therapy for Major Depressive Disorder and Bipolar Disorder

Enrollment
20 pts
Location
United States
Sponsor
Massachusetts General Hospital
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NCT06183359
Recruiting

Self-Identification Program

Enrollment
86 pts
Location
France
Sponsor
University Hospital, Montpelli...
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NCT06626152 Phase 2
Recruiting

Measuring Psychomotor Response to L-DOPA Challenge As a Biomarker for Outcomes in Late-Life Depression: a Pilot Feasibility Trial

Enrollment
50 pts
Location
Canada
Sponsor
University of British Columbia
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