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Clinical Trials by Phase

Clinical trials progress through four phases, each with different goals, sizes, and risk profiles. Browse active recruiting trials at each stage of development.

Trials Indexed
9,847

Clinical Trial Phase Overview

Phase 1
Safety
Phase 2
Efficacy
Phase 3
Approval
Phase 4
Monitor
Phase 1
575

Safety & dosing in 20–80 participants. First-in-human studies.

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Phase 2
1,078

Efficacy & side effects in 100–300 participants.

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①② Phase 1 / Phase 2
393

Combined early safety + preliminary efficacy assessment.

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Phase 3
542

Large-scale comparison vs. standard of care. 300–3,000+ participants.

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②③ Phase 2 / Phase 3
119

Bridging efficacy assessment with large-scale comparison.

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Phase 4
374

Post-market surveillance. Long-term safety in general population.

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N/A
6,766

Early-phase, observational, or studies not requiring phase designation.

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Phase data is sourced directly from ClinicalTrials.gov and reflects the trial's registered phase designation. Some trials span multiple phases (e.g. Phase 1/2). Counts reflect currently recruiting and active studies only.

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology