State MO
Clinical Trials in Missouri
Missouri is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Missouri and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 288 actively recruiting studies with Missouri sites out of 288 registered in total. The busiest research areas in Missouri are Obesity, Breast Cancer, Overweight. Leading sponsors running trials in the state include Washington University School of Medicine, National Cancer Institute (NCI), Merck Sharp & Dohme LLC. By stage, Missouri trials break down as Phase 1 (49), Phase 2 (87), Phase 3 (95), Phase 4 (11).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Missouri
Frequently Asked Questions — Clinical Trials in Missouri
How many clinical trials are currently recruiting in Missouri?
ClinicalMetric currently tracks 288 actively recruiting clinical trials with at least one location in Missouri. The total number of registered studies—including active but not currently enrolling trials—is 288. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Missouri?
Missouri hosts clinical trials across a broad range of medical conditions, including Obesity, Breast Cancer, Overweight, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Missouri serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Missouri?
To join a clinical trial in Missouri, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Missouri maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Missouri
NCT07158476 Phase 4
Recruiting
Efficacy of Methylprednisolone for Pain Control After ACL Repair
Condition
ACL Surgery
Enrollment
90 pts
Location
United States
Sponsor
St. Louis University
NCT06930625 Phase 3
Recruiting
A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acr...
Condition
Acromegaly
Enrollment
119 pts
Location
United States, Austria, Belgium
Sponsor
Debiopharm International SA
NCT07213804 Phase 3
Recruiting
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum...
Condition
Ovarian Neoplasms
Enrollment
1,630 pts
Location
United States, Australia, Austria
Sponsor
Eli Lilly and Company
NCT07577843 Phase 3
Recruiting
A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn...
Condition
Crohn Disease
Enrollment
460 pts
Location
United States, Argentina, Australia
Sponsor
Janssen Research & Development
NCT06350097 Phase 3
Recruiting
Phase III, Open-label Study of First-line Osimertinib With or Without Datopotama...
Condition
Non-small Cell Lung Cancer
Enrollment
582 pts
Location
United States, Australia, Brazil
Sponsor
AstraZeneca
NCT07392970 Phase 2
Recruiting
Motixafortide for MRD Sensitization in AML
Condition
Acute Myeloid Leukemia
Enrollment
10 pts
Location
United States
Sponsor
Washington University School o
NCT05685303 N/A
Recruiting
Alleviant ALLAY-HF Study
Condition
Heart Failure
Enrollment
700 pts
Location
United States, Australia, Austria
Sponsor
Alleviant Medical, Inc.
NCT06925542 Phase 1
Recruiting
A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory ...
Condition
SLE (Systemic Lupus)
Enrollment
80 pts
Location
United States, Germany, Spain
Sponsor
CRISPR Therapeutics
NCT07205718 Phase 1, Phase 2
Recruiting
A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors
Condition
Advanced or Metastatic Solid Tumors
Enrollment
273 pts
Location
United States
Sponsor
Takeda
NCT07532603 Phase 2, Phase 3
Recruiting
A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris
Condition
Lichen Planopilaris
Enrollment
342 pts
Location
United States, Australia, Canada
Sponsor
Priovant Therapeutics, Inc.
NCT07062588 Phase 2
Recruiting
Osteogenesis Imperfecta Trial of AGA2115 for ADUlts With COL1A1 and/or COL1A2 Ge...
Condition
Osteogenesis Imperfecta (OI)
Enrollment
80 pts
Location
United States, Argentina, Australia
Sponsor
Angitia Incorporated Limited
NCT07768345 Phase 3
Recruiting
A Study to Learn About Revaccination With a Vaccine Called RSVpreF in Immunocomp...
Condition
Respiratory Syncytial Virus (RSV)
Enrollment
440 pts
Location
United States
Sponsor
Pfizer
NCT05907629 N/A
Recruiting
Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vasc...
Condition
Stroke
Enrollment
300 pts
Location
United States
Sponsor
Yale University
NCT04221542 Phase 1
Recruiting
Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate C...
Condition
Prostate Cancer
Enrollment
505 pts
Location
United States, Australia, China
Sponsor
Amgen
NCT04889872 N/A
Recruiting
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAV...
Condition
Aortic Stenosis, Calcific
Enrollment
2,250 pts
Location
United States, Australia, Canada
Sponsor
Edwards Lifesciences
NCT03988283 Phase 1
Recruiting
Neoepitope-based Personalized DNA Vaccine Approach in Pediatric Patients With Re...
Condition
Pediatric Recurrent Central Nervous System Tumors
Enrollment
7 pts
Location
United States
Sponsor
Washington University School o
NCT04592445 N/A
Recruiting
Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having H...
Condition
Heart Failure With Preserved Ejection Fraction (HFpEF
Enrollment
150 pts
Location
United States, Georgia
Sponsor
Axon Therapies, Inc.
NCT07654361 Phase 3
Recruiting
Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight W...
Condition
Obesity
Enrollment
3,600 pts
Location
United States
Sponsor
Gasherbrum Bio, Inc., a wholly
NCT06001788 Phase 1
Recruiting
Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Ref...
Condition
AML
Enrollment
171 pts
Location
United States, Italy, Spain
Sponsor
Kura Oncology, Inc.
NCT05058651 Phase 2, Phase 3
Recruiting
Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemo...
Condition
Advanced Extrapulmonary Neuroendocrine Carcinoma
Enrollment
189 pts
Location
United States
Sponsor
National Cancer Institute (NCI
NCT00271180 N/A
Recruiting
Product Performance Report: Evaluate Long-term Reliability & Performance of Medt...
Condition
Arrhythmia
Enrollment
20,000 pts
Location
United States, Australia, Austria
Sponsor
Medtronic
NCT06651580 N/A
Recruiting
Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cance...
Condition
Chronic Pancreatitis
Enrollment
1,600 pts
Location
United States, Australia, Canada
Sponsor
M.D. Anderson Cancer Center
NCT05431088 Phase 2, Phase 3
Recruiting
A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCD
Condition
Sickle Cell Disease
Enrollment
389 pts
Location
United States, Brazil, India
Sponsor
Pfizer
NCT07784270 Phase 3
Recruiting
A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes...
Condition
Obesity or Overweight
Enrollment
1,500 pts
Location
United States, Argentina, Australia
Sponsor
AstraZeneca
NCT07110337 N/A
Recruiting
Diagnosing Epilepsy To EffeCT Change
Condition
Epilepsy
Enrollment
210 pts
Location
United States
Sponsor
Epiminder America, Inc.
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology