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stage ivb prostate cancer ajcc v8

Total Trials
6
Recruiting Now
6
Trial Phases
Phase 3, Phase 2, Phase 1

Cancer clinical trials represent the largest single category of recruiting studies worldwide, encompassing everything from early-phase safety studies of novel oncology drugs to large Phase 3 comparisons against current standard-of-care chemotherapy regimens. The field has accelerated dramatically with the rise of immunotherapy, targeted therapies, and CAR-T cell treatments that have transformed outcomes for previously untreatable malignancies.

Trials include checkpoint inhibitors (PD-1/PD-L1 agents), KRAS inhibitors, ADC (antibody-drug conjugates), combination chemotherapy regimens, radiation protocols, and surgical technique comparisons. Many trials stratify by biomarker status (PD-L1 expression, TMB, MSI-H) to identify patients most likely to benefit.

The NCI, pharmaceutical sponsors, and academic cancer centers collectively fund thousands of oncology trials annually across every cancer type.

Frequently Asked Questions — stage ivb prostate cancer ajcc v8 Clinical Trials

How many clinical trials are currently recruiting for stage ivb prostate cancer ajcc v8?
ClinicalMetric currently tracks 6 actively recruiting clinical trials for stage ivb prostate cancer ajcc v8, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 6. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for stage ivb prostate cancer ajcc v8?
stage ivb prostate cancer ajcc v8 research spans Phase 1 (2 trials), Phase 2 (2 trials), Phase 3 (2 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a stage ivb prostate cancer ajcc v8 clinical trial?
Eligibility criteria for stage ivb prostate cancer ajcc v8 trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
2
Phase 2
2
Phase 3
2
Top Sponsors
Alliance for Clinical Trials in Oncology 2 trials
University of Washington 1 trial
SWOG Cancer Research Network 1 trial
City of Hope Medical Center 1 trial
National Cancer Institute (NCI) 1 trial

Recruiting Clinical Trials

NCT06931340 Phase 3
Recruiting

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

Enrollment
1,260 pts
Location
United States
Sponsor
Alliance for Clinical Trials i...
View Trial →
NCT04489719
Recruiting

Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer

Enrollment
48 pts
Location
United States
Sponsor
University of Washington
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NCT06632977 Phase 2
Recruiting

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

Enrollment
474 pts
Location
United States
Sponsor
Alliance for Clinical Trials i...
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NCT06470243 Phase 3
Recruiting

Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body

Enrollment
528 pts
Location
United States
Sponsor
SWOG Cancer Research Network
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NCT05805371 Phase 1
Recruiting

PSCA-Targeting CAR-T Cells Plus or Minus Radiation for the Treatment of Patients With PSCA+ Metastatic Castration-Resistant Prostate Cancer

Enrollment
21 pts
Location
United States
Sponsor
City of Hope Medical Center
View Trial →
NCT04071236 Phase 1, Phase 2
Recruiting

Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation Enhancing Medication (M3814) Versus Radium-223 Dichloride Plus M3814 Plus Avelumab (a Type of Immunotherapy) for Advanced Prostate Cancer Not Responsive to Hormonal Therapy

Enrollment
90 pts
Location
United States
Sponsor
National Cancer Institute (NCI...
View Trial →
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology