State MO
Clinical Trials in Missouri
Missouri is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Missouri and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 275 actively recruiting studies with Missouri sites out of 275 registered in total. The busiest research areas in Missouri are Obesity, Heart Failure, Multiple Myeloma. Leading sponsors running trials in the state include Washington University School of Medicine, National Cancer Institute (NCI), AstraZeneca. By stage, Missouri trials break down as Phase 1 (52), Phase 2 (71), Phase 3 (78), Phase 4 (10).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Missouri
Frequently Asked Questions — Clinical Trials in Missouri
How many clinical trials are currently recruiting in Missouri?
ClinicalMetric currently tracks 275 actively recruiting clinical trials with at least one location in Missouri. The total number of registered studies—including active but not currently enrolling trials—is 275. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Missouri?
Missouri hosts clinical trials across a broad range of medical conditions, including Obesity, Heart Failure, Multiple Myeloma, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Missouri serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Missouri?
To join a clinical trial in Missouri, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Missouri maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Missouri
NCT05933707 N/A
Recruiting
Small Extracellular Vesicles and Insulin Action
Condition
Obesity
Enrollment
72 pts
Location
United States
Sponsor
Washington University School o
NCT05654012 N/A
Recruiting
Migraine in Adolescents
Condition
Migraine
Enrollment
250 pts
Location
United States
Sponsor
Washington University School o
NCT06740630 Phase 3
Recruiting
A Study on the Immune Response and Safety of an Investigational Chickenpox Vacci...
Condition
Chickenpox
Enrollment
1,840 pts
Location
United States, Belgium, Colombia
Sponsor
GlaxoSmithKline
NCT07421700 Phase 1, Phase 2
Recruiting
Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With...
Condition
Urothelial Cancer
Enrollment
132 pts
Location
United States, Australia, China
Sponsor
Pfizer
NCT03823534 Phase 3
Recruiting
Post-Op Pain Control for Prophylactic Intramedullary Nailing.
Condition
Bone Metastases
Enrollment
60 pts
Location
United States
Sponsor
St. Louis University
NCT05677971 Phase 3
Recruiting
Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People ...
Condition
Alpha1-Antitrypsin Deficiency
Enrollment
160 pts
Location
United States, Australia, Austria
Sponsor
Takeda
NCT06247787 Phase 1
Recruiting
A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine a...
Condition
Recurrent Childhood Acute Myeloid Leukemia
Enrollment
36 pts
Location
United States
Sponsor
Children's Oncology Group
NCT06736574 Phase 3
Recruiting
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With S...
Condition
Heart Failure
Enrollment
1,800 pts
Location
United States, Canada, China
Sponsor
Cytokinetics
NCT07158476 Phase 4
Recruiting
Efficacy of Methylprednisolone for Pain Control After ACL Repair
Condition
ACL Surgery
Enrollment
90 pts
Location
United States
Sponsor
St. Louis University
NCT03266640 Phase 2
Recruiting
Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CM...
Condition
Cytomegalovirus Infections
Enrollment
20 pts
Location
United States
Sponsor
New York Medical College
NCT07339423 Phase 3
Recruiting
AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps...
Condition
Obesity
Enrollment
1,150 pts
Location
United States, Argentina, Australia
Sponsor
Novo Nordisk A/S
NCT06726148 Phase 1, Phase 2
Recruiting
Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER...
Condition
Advanced HR+/HER2- Breast Cancer
Enrollment
280 pts
Location
United States, Australia, Canada
Sponsor
Novartis Pharmaceuticals
NCT06057935 Phase 2
Recruiting
A Study of Additional Chemotherapy After Surgery for People With Malignant Perit...
Condition
Malignant Peritoneal Mesothelioma
Enrollment
64 pts
Location
United States
Sponsor
Memorial Sloan Kettering Cance
NCT06425848 N/A
Recruiting
HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry
Condition
Heart Failure
Enrollment
2,000 pts
Location
United States
Sponsor
University of Kansas Medical C
NCT04372615 Phase 2
Recruiting
The ExTINGUISH Trial of Inebilizumab in NMDAR Encephalitis
Condition
Autoimmune Encephalitis
Enrollment
116 pts
Location
United States, Netherlands, Spain
Sponsor
University of Utah
NCT07645248 Phase 3
Recruiting
A Study to Compare Safety of 4 Weeks Exposure to Propellants Hydrofluoroalkane 1...
Condition
Asthma
Enrollment
110 pts
Location
United States, Argentina, Canada
Sponsor
GlaxoSmithKline
NCT05701917 N/A
Recruiting
DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombos...
Condition
Venous Thromboembolism
Enrollment
300 pts
Location
United States, Austria, Finland
Sponsor
Inari Medical
NCT07118358 N/A
Recruiting
BIOTRONIK Investigation of the LivIQ Leadless Pacemaker System
Condition
Leadless Pacemaker
Enrollment
325 pts
Location
United States, Australia, Austria
Sponsor
Biotronik, Inc.
NCT06969287 Phase 3
Recruiting
Mitigating Delirium With Fluvoxamine Treatment for Non-Cardiac Surgery
Condition
Delirium
Enrollment
46 pts
Location
United States
Sponsor
Washington University School o
NCT07140913 Phase 3
Recruiting
A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatmen...
Condition
Mania
Enrollment
424 pts
Location
United States, Argentina, Bulgaria
Sponsor
Bristol-Myers Squibb
NCT07629440 Phase 3
Recruiting
A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.
Condition
Pneumococcal Disease
Enrollment
3,230 pts
Location
United States, Japan, Puerto Rico
Sponsor
Pfizer
NCT03373968 Phase 2, Phase 3
Recruiting
Givinostat in Duchenne's Muscular Dystrophy Long-term Safety and Tolerability St...
Condition
Duchenne Muscular Dystrophy
Enrollment
206 pts
Location
United States, Belgium, Canada
Sponsor
Italfarmaco
NCT03619850 Phase 3
Recruiting
A Study to Evaluate the Safety (Compared to Iron Sucrose), Efficacy and Pharmaco...
Condition
Chronic Kidney Disease; Iron Deficiency Anemia
Enrollment
129 pts
Location
United States, Hungary, Lithuania
Sponsor
AMAG Pharmaceuticals, Inc.
NCT06867185 N/A
Recruiting
Evaluating Therapeutic Electrical Stimulation to Improve Nerve Healing After Sur...
Condition
Digital Nerve Injury
Enrollment
60 pts
Location
United States
Sponsor
Checkpoint Surgical Inc.
NCT06312176 Phase 3
Recruiting
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combinatio...
Condition
Breast Neoplasms
Enrollment
1,200 pts
Location
United States, Argentina, Australia
Sponsor
Merck Sharp & Dohme LLC
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology