State MO
Clinical Trials in Missouri
Missouri is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Missouri and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 286 actively recruiting studies with Missouri sites out of 286 registered in total. The busiest research areas in Missouri are Obesity, Carcinoma, Non-Small-Cell Lung, Multiple Myeloma. Leading sponsors running trials in the state include Washington University School of Medicine, National Cancer Institute (NCI), AstraZeneca. By stage, Missouri trials break down as Phase 1 (40), Phase 2 (81), Phase 3 (88), Phase 4 (6).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Missouri
Obesity (6)Carcinoma, Non-Small-Cell Lung (5)Multiple Myeloma (4)Myelodysplastic Syndromes (4)Advanced Solid Tumor (4)Alzheimer Disease (4)Heart Failure (4)Cardiovascular Diseases (4)Smoking Cessation (4)Acute Myeloid Leukemia (4)B Acute Lymphoblastic Leukemia (3)Pancreatic Ductal Adenocarcinoma (3)
Frequently Asked Questions — Clinical Trials in Missouri
How many clinical trials are currently recruiting in Missouri?
ClinicalMetric currently tracks 286 actively recruiting clinical trials with at least one location in Missouri. The total number of registered studies—including active but not currently enrolling trials—is 286. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Missouri?
Missouri hosts clinical trials across a broad range of medical conditions, including Obesity, Carcinoma, Non-Small-Cell Lung, Multiple Myeloma, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Missouri serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Missouri?
To join a clinical trial in Missouri, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Missouri maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Missouri
NCT06827990 N/A
Recruiting
GORE® Ascending Stent Graft in the Treatment of De Novo Type A Aortic Dissection...
Condition
Aortic Dissection
Enrollment
112 pts
Location
United States
Sponsor
W.L.Gore & Associates
NCT07110246 Phase 2
Recruiting
Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas
Condition
BRAF V600 Mutation
Enrollment
96 pts
Location
United States
Sponsor
University of California, San
NCT07166120 N/A
Recruiting
Precision Treatment to Promote Smoking Cessation and Survival in Oncology Patien...
Condition
Smoking Cessation
Enrollment
132 pts
Location
United States
Sponsor
Washington University School o
NCT05549297 Phase 3
Recruiting
Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced ...
Condition
Advanced Melanoma
Enrollment
540 pts
Location
United States, Australia, Austria
Sponsor
Immunocore Ltd
NCT01656603 Phase 2
Recruiting
Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cor...
Condition
Infusion Reactions
Enrollment
9,999 pts
Location
United States
Sponsor
New York Blood Center
NCT07479797 Phase 3
Recruiting
Study Evaluating the Efficacy of KITE-753 Versus Axicabtagene Ciloleucel in Part...
Condition
Relapsed or Refractory Large B-cell Lymphoma
Enrollment
550 pts
Location
United States, Australia, Canada
Sponsor
Kite, A Gilead Company
NCT07036523 Phase 2
Recruiting
A Study to Find Out Whether BI 765423 Has an Effect on Lung Function in People W...
Condition
Idiopathic Pulmonary Fibrosis
Enrollment
71 pts
Location
United States, Australia, Belgium
Sponsor
Boehringer Ingelheim
NCT05442957 N/A
Recruiting
Building a Renewed ImaGe After Head & Neck Cancer Treatment (BRIGHT) Multi-Site ...
Condition
Head and Neck Cancer
Enrollment
180 pts
Location
United States
Sponsor
Medical University of South Ca
NCT06293053 Phase 3
Recruiting
A Study to Investigate the Pharmacokinetics and Safety of Dupilumab in Participa...
Condition
Prurigo Nodularis
Enrollment
18 pts
Location
United States
Sponsor
Sanofi
NCT04855656 Phase 1
Recruiting
Study of Lunresertib Alone or in Combination With RP-3500 or Debio 0123 in Patie...
Condition
Advanced Solid Tumor
Enrollment
464 pts
Location
United States, Canada, Denmark
Sponsor
Debiopharm International SA
NCT05940857 N/A
Recruiting
US National OCS Liver Perfusion (OLP) Registry
Condition
Liver Transplant
Enrollment
100,000 pts
Location
United States
Sponsor
TransMedics
NCT07213973 Phase 2
Recruiting
Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participant...
Condition
Hidradenitis Suppurativa (HS)
Enrollment
40 pts
Location
United States, Canada
Sponsor
Incyte Corporation
NCT04629469 N/A
Recruiting
Low Field and High Field Magnetic Resonance Imaging Assessments on Pediatric Pat...
Condition
Conditions Requiring a Brain Magnetic Resonance Imaging, Head Computerized Tomography, or Head Ultrasound
Enrollment
250 pts
Location
United States
Sponsor
Children's Mercy Hospital Kans
NCT07218146 Phase 3
Recruiting
A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With ...
Condition
Small-cell Lung Cancer
Enrollment
480 pts
Location
United States, Austria, Belgium
Sponsor
Zai Lab (Shanghai) Co., Ltd.
NCT03448926 N/A
Recruiting
The PREDICT Registry:
Condition
DCIS
Enrollment
3,000 pts
Location
United States
Sponsor
PreludeDx
NCT06628908 Phase 3
Recruiting
Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabet...
Condition
Diabetic Peripheral Neuropathic Pain
Enrollment
1,100 pts
Location
United States
Sponsor
Vertex Pharmaceuticals Incorpo
NCT06560307 N/A
Recruiting
Study of Enhanced Programming Stimulation with the Enterra® Therapy System
Condition
Gastroparesis
Enrollment
50 pts
Location
United States
Sponsor
Enterra Medical, Inc.
NCT07473778 N/A
Recruiting
Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention
Condition
HIV Infections
Enrollment
3,000 pts
Location
United States
Sponsor
Gilead Sciences
NCT04153292 N/A
Recruiting
The ENCIRCLE Trial
Condition
Mitral Regurgitation
Enrollment
900 pts
Location
United States, Australia, Canada
Sponsor
Edwards Lifesciences
NCT07598136 N/A
Recruiting
A Study to Determine the Effects of ENDS Flavor Availability on Abstinence Withi...
Condition
Smoking
Enrollment
1,280 pts
Location
United States
Sponsor
RAI Services Company
NCT06344052 Phase 2
Recruiting
To Assess the Safety and Efficacy of SP-002 with Vismodegib for the Treatment of...
Condition
Basal Cell Carcinoma
Enrollment
80 pts
Location
United States
Sponsor
Stamford Pharmaceuticals, Inc.
NCT07815678 Phase 1, Phase 2
Recruiting
First-in-human Study of the Safety, Tolerability, Pharmacokinetics, and Food Eff...
Condition
Obesity
Enrollment
164 pts
Location
United States
Sponsor
Aconcagua Bio, Inc. a wholly o
NCT05986292 Phase 2
Recruiting
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices ...
Condition
Osteoarthritis, Knee
Enrollment
10,000 pts
Location
United States, Puerto Rico
Sponsor
Eli Lilly and Company
NCT06767514 Phase 3
Recruiting
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patie...
Condition
Non-Small Cell Lung Cancer
Enrollment
780 pts
Location
United States, Belgium, Canada
Sponsor
Summit Therapeutics
NCT06203600 Phase 2, Phase 3
Recruiting
Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophage...
Condition
Advanced Esophageal Adenocarcinoma
Enrollment
224 pts
Location
United States
Sponsor
National Cancer Institute (NCI
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology