State MO
Clinical Trials in Missouri
Missouri is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Missouri and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 275 actively recruiting studies with Missouri sites out of 275 registered in total. The busiest research areas in Missouri are Obesity, Heart Failure, Multiple Myeloma. Leading sponsors running trials in the state include Washington University School of Medicine, National Cancer Institute (NCI), AstraZeneca. By stage, Missouri trials break down as Phase 1 (52), Phase 2 (71), Phase 3 (78), Phase 4 (10).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Missouri
Frequently Asked Questions — Clinical Trials in Missouri
How many clinical trials are currently recruiting in Missouri?
ClinicalMetric currently tracks 275 actively recruiting clinical trials with at least one location in Missouri. The total number of registered studies—including active but not currently enrolling trials—is 275. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Missouri?
Missouri hosts clinical trials across a broad range of medical conditions, including Obesity, Heart Failure, Multiple Myeloma, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Missouri serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Missouri?
To join a clinical trial in Missouri, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Missouri maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Missouri
NCT06994676 Phase 1
Recruiting
A Study of CBX-250 in Participants With Relapsed or Refractory Myeloid Leukemias
Condition
High-risk Myelodysplastic Syndrome
Enrollment
72 pts
Location
United States
Sponsor
Crossbow Therapeutics, Inc.
NCT07223840 Phase 2
Recruiting
A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid R...
Condition
Smoking
Enrollment
222 pts
Location
United States, China, Japan
Sponsor
Eli Lilly and Company
NCT07574593 N/A
Recruiting
NORM-HF Pivotal Study
Condition
Heart Failure
Enrollment
800 pts
Location
United States
Sponsor
Foundry Innovation & Research
NCT06030063 N/A
Recruiting
The Society for Obstetric Anesthesia and Perinatology Research Network General A...
Condition
Cesarean Delivery
Enrollment
5,000 pts
Location
United States, Canada
Sponsor
Yale University
NCT06965504 N/A
Recruiting
INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure ...
Condition
Heart Failure
Enrollment
250 pts
Location
United States
Sponsor
Abiomed Inc.
NCT00009633 N/A
Recruiting
Follow-up Visit of High Risk Infants
Condition
Infant, Newborn
Enrollment
68,000 pts
Location
United States
Sponsor
NICHD Neonatal Research Networ
NCT05718063 N/A
Recruiting
MAP for Coaches: Translating Sports Injury Prevention Knowledge to Youth Sport C...
Condition
Knowledge, Attitudes, Practice
Enrollment
200 pts
Location
United States
Sponsor
St. Louis University
NCT06915363 N/A
Recruiting
BioPoly® Partial Resurfacing Knee Implant IDE
Condition
Knee Pain Chronic
Enrollment
152 pts
Location
United States
Sponsor
BioPoly LLC
NCT06896916 Phase 1
Recruiting
Study of Intravenously (IV) Infused Etentamig in Combination With an Oral Cerebl...
Condition
Multiple Myeloma
Enrollment
135 pts
Location
United States, Australia, Canada
Sponsor
AbbVie
NCT07656285 N/A
Recruiting
Comparison of Immediate Changes in Cervical Range of Motion Following Cervical E...
Condition
Cervical Disease
Enrollment
128 pts
Location
United States
Sponsor
Missouri State University
NCT06747117 N/A
Recruiting
A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus ...
Condition
Lower Extremity Acute Limb Ischemia
Enrollment
300 pts
Location
United States, Australia, Brazil
Sponsor
Penumbra Inc.
NCT03965143 N/A
Recruiting
Talus Replacement Registry
Condition
Avascular Necrosis of the Talus
Enrollment
50 pts
Location
United States
Sponsor
Kyle Schweser MD
NCT06628908 Phase 3
Recruiting
Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabet...
Condition
Diabetic Peripheral Neuropathic Pain
Enrollment
1,100 pts
Location
United States
Sponsor
Vertex Pharmaceuticals Incorpo
NCT07489417 N/A
Recruiting
Impact of Sleep Restriction on Blood Pressure Reactivity
Condition
Sleep
Enrollment
45 pts
Location
United States
Sponsor
University of Missouri-Columbi
NCT04792489 Phase 2
Recruiting
DALY II USA/ MB-CART2019.1 for DLBCL
Condition
Refractory Diffuse Large B Cell Lymphoma (DLBCL)
Enrollment
315 pts
Location
United States, Canada
Sponsor
Miltenyi Biomedicine GmbH
NCT06625385 N/A
Recruiting
A Study Evaluating the Safety and Efficacy of the 3M™ V.A.C. Peel and Place Dres...
Condition
Wound
Enrollment
90 pts
Location
United States
Sponsor
Solventum US LLC
NCT04649242 Phase 3
Recruiting
Randomized Study in Children and Adolescents With Migraine: Acute Treatment
Condition
Pediatric Migraine
Enrollment
2,100 pts
Location
United States, Canada, China
Sponsor
Pfizer
NCT07082738 Phase 2
Recruiting
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Ve...
Condition
Chronic Obstructive Pulmonary Disease (COPD)
Enrollment
987 pts
Location
United States, Argentina, Australia
Sponsor
AstraZeneca
NCT05277558 N/A
Recruiting
Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Typ...
Condition
Type2 Diabetes
Enrollment
117 pts
Location
United States
Sponsor
Washington University School o
NCT06440005 Phase 1
Recruiting
A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in P...
Condition
Cancer
Enrollment
80 pts
Location
United States
Sponsor
Angiex, Inc.
NCT06750094 Phase 3
Recruiting
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in P...
Condition
Colorectal Neoplasms
Enrollment
700 pts
Location
United States, Australia, Belgium
Sponsor
Janssen Research & Development
NCT05803941 Phase 4
Recruiting
Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With ...
Condition
Prostate Cancer
Enrollment
700 pts
Location
United States, Austria, Belgium
Sponsor
Novartis Pharmaceuticals
NCT07566156 Phase 3
Recruiting
Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradioth...
Condition
Urothelial Cancer
Enrollment
390 pts
Location
United States, Canada, South Korea
Sponsor
Astellas Pharma Global Develop
NCT07227311 Phase 2
Recruiting
A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combinati...
Condition
Multiple Myeloma
Enrollment
200 pts
Location
United States, France, Germany
Sponsor
GlaxoSmithKline
NCT06252649 Phase 3
Recruiting
Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevac...
Condition
Metastatic Colorectal Cancer
Enrollment
450 pts
Location
United States, Argentina, Australia
Sponsor
Amgen
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology