NCT07218133 Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery
| NCT ID | NCT07218133 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Alexander T. Yahanda |
| Condition | Spinal Fusion |
| Study Type | INTERVENTIONAL |
| Enrollment | 50 participants |
| Start Date | 2025-10-08 |
| Primary Completion | 2026-05 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 50 participants in total. It began in 2025-10-08 with a primary completion date of 2026-05.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study is a randomized controlled trial that will evaluate the effect of non-invasive auricular vagal nerve stimulation on inflammatory markers, glycemic control, postoperative pain, and inflammation-related clinical outcomes after long-segment spinal fusion surgeries when compared to current accepted management.
Eligibility Criteria
Inclusion Criteria: * Long-segment spinal fusions (defined as constructs spanning at least L2-pelvis for thoracolumbar fusions or C2-T2 for cervical fusions) * Ability to undergo a reliable neurologic examination and pain assessments Exclusion Criteria: * Patients \<18 years of age * Shorter-segment spinal fusions than those described above * Undergoing current active cancer therapy * Undergoing treatment with immunosuppressive drugs * Additional spinal surgery within past 6 months * Sustained bradycardia or presence of pacemaker * History of substance abuse
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07218133 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Spinal Fusion. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07218133 currently recruiting?
Yes, NCT07218133 is actively recruiting participants. Contact the research team at ayahanda@wustl.edu for enrollment information.
Where is the NCT07218133 trial being conducted?
This trial is being conducted at St Louis, United States.
Who is sponsoring the NCT07218133 clinical trial?
NCT07218133 is sponsored by Alexander T. Yahanda. The trial plans to enroll 50 participants.