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Medical Condition
multiple myeloma
Total Trials
54
Recruiting Now
54
Trial Phases
Phase 2, Phase 1, Phase 2, Phase 4
ClinicalMetric tracks all active clinical trials for multiple myeloma sourced from ClinicalTrials.gov. Each listing includes the NCT identifier, current recruitment status, phase, primary endpoints, sponsor, estimated enrollment, and participating countries — updated daily as new studies open and status changes.
- Recruiting trials currently enrolling participants, with eligibility criteria and age requirements
- Phase 1–4 studies from early safety trials to post-marketing surveillance
- NIH, pharmaceutical sponsor, and academic medical center studies worldwide
- AI-powered plain-language summary available for every trial listing
Frequently Asked Questions — multiple myeloma Clinical Trials
How many clinical trials are currently recruiting for multiple myeloma?
ClinicalMetric currently tracks 54 actively recruiting clinical trials for multiple myeloma, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 54. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for multiple myeloma?
multiple myeloma research spans Phase 1 (16 trials), Phase 2 (22 trials), Phase 3 (4 trials), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a multiple myeloma clinical trial?
Eligibility criteria for multiple myeloma trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1 16
Phase 2 22
Phase 3 4
Phase 4 1
Top Sponsors
3 trials
3 trials
2 trials
2 trials
2 trials
Recruiting Clinical Trials
NCT05336383 Phase 2
Recruiting
Phase II Study of Salvage Radiation Treatment After B-cell Maturation Antigen Chimeric Antigen Receptor T-cell Therapy for Relapsed Refractory Multiple Myeloma
Enrollment
30 pts
Location
United States
Sponsor
M.D. Anderson Cancer Center
NCT05632380 Phase 1, Phase 2
Recruiting
ASCT in Combination With C-CAR088 for Treating Patients With Ultra High-risk Multiple Myeloma (MM)
Enrollment
20 pts
Location
China
Sponsor
Institute of Hematology & Bloo...
NCT06793449 Phase 2
Recruiting
BCMA CAR-T Versus ASCT in Transplant-eligible Patients With Multiple Myeloma
Enrollment
80 pts
Location
China
Sponsor
Institute of Hematology & Bloo...
NCT05201781 Phase 4
Recruiting
A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel
Enrollment
295 pts
Location
United States, Belgi...
Sponsor
Janssen Research & Development...
NCT04114084
Recruiting
Sleep Apnea in Patients With MGUS and MM
Enrollment
200 pts
Location
United States
Sponsor
Michael Tomasson
NCT06485076
Recruiting
Early Palliative Care for Patients With Multiple Myeloma and Aggressive Lymphoma
Enrollment
144 pts
Location
Canada
Sponsor
University Health Network, Tor...
NCT06896916 Phase 1
Recruiting
Study of Intravenously (IV) Infused Etentamig in Combination With an Oral Cereblon E3 Ligase Modulatory Drug (CELMoD) Agent Assessing Adverse Events and Change in Disease Activity in Adult Participants With Relapsed or Refractory Multiple Myeloma
Enrollment
135 pts
Location
United States, Austr...
Sponsor
AbbVie
NCT05299424 Phase 1, Phase 2
Recruiting
A Study of CM336 in Patients With Relapsed or Refractory Multiple Myeloma
Enrollment
48 pts
Location
China
Sponsor
Keymed Biosciences Co.Ltd
NCT07333261 Phase 1
Recruiting
Study of BMS-986453 in Newly Diagnosed Multiple Myeloma
Enrollment
25 pts
Location
United States
Sponsor
Susan Bal
NCT06980480 Phase 3
Recruiting
A Study of Gammagard Liquid (Immune Globulin Infusion, 10%) to Prevent Infections in Adults With Multiple Myeloma
Enrollment
183 pts
Location
United States, Austr...
Sponsor
Takeda
NCT06910670
Recruiting
Implementing a Randomized Control Trial to Test the Expanded Web-based Decision Aid
Enrollment
240 pts
Location
United States
Sponsor
Washington University School o...
NCT07200102 Phase 1
Recruiting
Selinexor Maintenance Post CAR-T Cell Therapy for Multiple Myeloma
Enrollment
20 pts
Location
United States
Sponsor
Washington University School o...
NCT06376526 Phase 2
Recruiting
IMMUNOPLANT for Newly Diagnosed Multiple Myeloma
Enrollment
28 pts
Location
United States
Sponsor
Dickran Kazandjian, MD
NCT03761108 Phase 1, Phase 2
Recruiting
Phase 1/2 Study of Linvoseltamab in Adult Patients With Relapsed or Refractory Multiple Myeloma
Enrollment
387 pts
Location
United States, Belgi...
Sponsor
Regeneron Pharmaceuticals
NCT05366881
Recruiting
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
Enrollment
7,000 pts
Location
United States
Sponsor
Adela, Inc
NCT06500884 Phase 2
Recruiting
A Study to Evaluate Preventive Treatments for GPRC5D-related Oral Events
Enrollment
210 pts
Location
United States, Brazi...
Sponsor
Janssen Research & Development...
NCT03909412 Phase 1
Recruiting
Carfilzomib Based Chemotherapy Mobilization for Autologous Stem Cell Transplants in Multiple Myeloma
Enrollment
18 pts
Location
United States
Sponsor
Hackensack Meridian Health
NCT03689595
Recruiting
Predicting Progression of Developing Myeloma in a High-Risk Screened Population (PROMISE)
Enrollment
30,000 pts
Location
United States
Sponsor
Dana-Farber Cancer Institute
NCT06296121 Phase 3
Recruiting
A Study of the Efficacy and Safety of Monotherapy With BCD-264 and Darzalex in Subjects With Relapsed and Refractory Multiple Myeloma
Enrollment
252 pts
Location
Russia
Sponsor
Biocad
NCT05243797 Phase 3
Recruiting
Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation
Enrollment
1,594 pts
Location
United States, Argen...
Sponsor
European Myeloma Network B.V.
NCT05243212 Phase 1, Phase 2
Recruiting
Study of CAR-BCMA, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against BCMA in Subjects With Multiple Myeloma
Enrollment
75 pts
Location
Israel
Sponsor
Sheba Medical Center
NCT06028087
Recruiting
Real-World Mapping Antithrombotic Regimens in MM Patients on Treatment
Enrollment
736 pts
Location
Italy
Sponsor
Gruppo Italiano Malattie EMato...
NCT05737732
Recruiting
The Ambient Light Multiple Myeloma Study
Enrollment
200 pts
Location
United States
Sponsor
Icahn School of Medicine at Mo...
NCT04533217
Recruiting
Examination of Vertebroplasty in Addition to Regular Treatment of Patients With Multiple Myeloma.
Enrollment
90 pts
Location
Denmark
Sponsor
Spine Centre of Southern Denma...
NCT06759181 Phase 1, Phase 2
Recruiting
Safety and Efficacy of Anti-BCMA/FcRL5 CAR-T Cell Therapy in Treating Relapsed and Refractory Multiple Myeloma (R/R MM)
Enrollment
20 pts
Location
China
Sponsor
Xuzhou Medical University
NCT06789003
Recruiting
Evaluation of a PREHABilitation Protocol Using Adapted Physical Activity (APA) for Multiple Myeloma Patients Eligible for Intensive Autologous Stem Cell Transplantation Treatment
Enrollment
120 pts
Location
France
Sponsor
Centre Hospitalier Henri Duffa...
NCT06082284
Recruiting
A Cross-sectional Study on the Positive Rate of M Protein Based on a Highly Sensitive Serum M Protein Detection Method.
Enrollment
10,000 pts
Location
China
Sponsor
Zhujiang Hospital
NCT03717844
Recruiting
Registry for Adults With Plasma Cell Disorders (PCD's)
Enrollment
2,000 pts
Location
United States
Sponsor
UNC Lineberger Comprehensive C...
NCT04776330 Phase 1, Phase 2
Recruiting
a Clinical Research of BCMA-Targeted Prime CAR-T Cell Therapy in Relapsed/Refractory Multiple Myeloma and Plasma Cell Disease
Enrollment
80 pts
Location
China
Sponsor
Chongqing Precision Biotech Co...
NCT07111884
Recruiting
GMMG Multiple Myeloma Registry
Enrollment
999 pts
Location
Germany
Sponsor
Prof. Dr. Hartmut Goldschmidt
NCT07073547 Phase 1
Recruiting
A Phase I, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Immunogenicity, Pharmacodynamics, and Preliminary Efficacy of AZD0120 in Participants With Multiple Myeloma (DURGA-2)
Enrollment
40 pts
Location
United States
Sponsor
AstraZeneca
NCT04176718 Phase 2
Recruiting
Daratumumab, Carfilzomib, Pomalidomide, Dexamethasone In MM
Enrollment
43 pts
Location
United States
Sponsor
Andrew Yee, MD
NCT07188090 Phase 2
Recruiting
Mozobil for Autologous Hematopoietic Stem Cell Transplantation
Enrollment
100 pts
Location
United States
Sponsor
Thomas Jefferson University
NCT06235229 Phase 1, Phase 2
Recruiting
A Study of GC012F in Patients With Relapsed/Refractory Multiple Myeloma
Enrollment
110 pts
Location
China
Sponsor
Gracell Biotechnologies (Shang...
NCT07226934
Recruiting
An AI-Generated, Personalized Question Prompt List Intervention for Patients With Hematologic Cancers
Enrollment
40 pts
Location
United States
Sponsor
Washington University School o...
NCT06103838 Phase 2
Recruiting
18F-Fluciclovine PET/CT in Multiple Myeloma
Enrollment
60 pts
Location
United States
Sponsor
National Cancer Institute (NCI...
NCT05646576
Recruiting
Defining the Role of Palliative carE for Patients With Hematologic Malignancies Undergoing Adoptive CEllular Therapy
Enrollment
90 pts
Location
United States
Sponsor
Massachusetts General Hospital
NCT06484777 Phase 1
Recruiting
A Clinical Study of SHR-9539 in Patients With Multiple Myeloma
Enrollment
138 pts
Location
China
Sponsor
Suzhou Suncadia Biopharmaceuti...
NCT06515249
Recruiting
Integrative Therapies in Multiple Myeloma
Enrollment
300 pts
Location
Israel
Sponsor
Bnai Zion Medical Center
NCT07227311 Phase 2
Recruiting
A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With Standard of Care in Participants With Relapsed-Refractory Multiple Myeloma (RRMM)
Enrollment
200 pts
Location
United States, Japan
Sponsor
GlaxoSmithKline
NCT06409767
Recruiting
Impact of an Early Warning System on the Prognosis of Patients With Hematological Malignancies Receiving Intensive Chemotherapy With or Without Hematopoietic Cell Transplantation.
Enrollment
2,224 pts
Location
France
Sponsor
University Hospital, Angers
NCT05828511 Phase 1, Phase 2
Recruiting
A Window of Opportunity Trial to Learn if Linvoseltamab is Safe and Well Tolerated, and How Well it Works in Adult Participants With Recently Diagnosed Multiple Myeloma Who Have Not Already Received Treatment
Enrollment
149 pts
Location
United States, Franc...
Sponsor
Regeneron Pharmaceuticals
NCT02869555
Recruiting
Institut Paoli Calmettes Multiple Myeloma Database
Enrollment
5,000 pts
Location
France
Sponsor
Institut Paoli-Calmettes
NCT05969860 Phase 2
Recruiting
At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer
Enrollment
220 pts
Location
United States
Sponsor
Mayo Clinic
NCT06100237 Phase 2
Recruiting
Teclistamab in Combination With Daratumumab for High-Risk Smoldering Myeloma: A Clinical and Correlative Phase 2 Immuno-Oncology Study (the REVIVE Study)
Enrollment
50 pts
Location
United States
Sponsor
Carl Ola Landgren, MD, PhD
NCT06561854 Phase 3
Recruiting
Study Comparing Therapy for Advanced Relapsed/Refractory Multiple Myeloma With and Without Dexamethasone
Enrollment
318 pts
Location
France
Sponsor
Assistance Publique - Hôpitaux...
NCT07169500 Phase 1, Phase 2
Recruiting
Clinical Study on the Safety and Efficacy of BCMA-CART±ASCT in Treating Young Multiple Myeloma Patients
Enrollment
50 pts
Location
China
Sponsor
Institute of Hematology & Bloo...
NCT06993675 Phase 2
Recruiting
Engaging T-cells to Eliminate MRD in Newly Diagnosed Myeloma Optimizing Response With Talquetmab and Teclistamab (ROTATE)
Enrollment
50 pts
Location
United States
Sponsor
Noffar Bar
NCT06644625
Recruiting
CHAAMP (CHArlotte Advocate MGUS Project) Internal Pilot Study
Enrollment
1,665 pts
Location
United States
Sponsor
Wake Forest University Health ...
NCT00898235
Recruiting
Collection of Samples and Clinical Data From Patients With Amyloid Diseases
Enrollment
10,000 pts
Location
United States
Sponsor
Boston Medical Center
NCT03297606 Phase 2
Recruiting
Canadian Profiling and Targeted Agent Utilization Trial (CAPTUR)
Enrollment
720 pts
Location
Canada
Sponsor
Canadian Cancer Trials Group
NCT06497738
Recruiting
A Prospective Study Comparing DRd With VRd-lite in Elderly Newly Diagnosed Multiple Myeloma
Enrollment
112 pts
Location
China
Sponsor
The First Affiliated Hospital ...
NCT06132711 Phase 1, Phase 2
Recruiting
Safety and Efficacy of APRIL-BAFF-Bicephali CAR-T in Relapsed, Refractory Multiple Myeloma
Enrollment
20 pts
Location
China
Sponsor
Xuzhou Medical University
NCT06252792
Recruiting
Dara-PD in the Treatment of Patients With First Relapse of Multiple Myeloma
Enrollment
50 pts
Location
China
Sponsor
FengYan Jin
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: April 2026 · Data Methodology