State MO
Clinical Trials in Missouri
Missouri is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Missouri and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 270 actively recruiting studies with Missouri sites out of 270 registered in total. The busiest research areas in Missouri are Breast Cancer, Prostate Cancer, Multiple Myeloma. Leading sponsors running trials in the state include Washington University School of Medicine, National Cancer Institute (NCI), University of Missouri-Columbia. By stage, Missouri trials break down as Phase 1 (53), Phase 2 (82), Phase 3 (85), Phase 4 (10).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Missouri
Frequently Asked Questions — Clinical Trials in Missouri
How many clinical trials are currently recruiting in Missouri?
ClinicalMetric currently tracks 270 actively recruiting clinical trials with at least one location in Missouri. The total number of registered studies—including active but not currently enrolling trials—is 270. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Missouri?
Missouri hosts clinical trials across a broad range of medical conditions, including Breast Cancer, Prostate Cancer, Multiple Myeloma, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Missouri serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Missouri?
To join a clinical trial in Missouri, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Missouri maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Missouri
NCT04469530 Phase 2
Recruiting
Sirolimus in Combination With Metronomic Chemotherapy in Children With High-Risk...
Condition
Solid Tumor
Enrollment
55 pts
Location
United States
Sponsor
Emory University
NCT04949464 N/A
Recruiting
Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoki...
Condition
HIV Infection
Enrollment
100 pts
Location
United States
Sponsor
AIDS Malignancy Consortium
NCT07284472 Phase 2, Phase 3
Recruiting
Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzh...
Condition
Agitation Associated With Alzheimer's Disease Dementia
Enrollment
300 pts
Location
United States, Canada, Czechia
Sponsor
Exciva GmbH
NCT04176198 Phase 1, Phase 2
Recruiting
A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis
Condition
Myelofibrosis
Enrollment
240 pts
Location
United States, Australia, Belgium
Sponsor
Sumitomo Pharma America, Inc.
NCT07288398 Phase 3
Recruiting
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
Condition
Pulmonary Hypertension Associated With HFpEF
Enrollment
540 pts
Location
United States, Argentina, Austria
Sponsor
Tenax Therapeutics, Inc.
NCT00009633 N/A
Recruiting
Follow-up Visit of High Risk Infants
Condition
Infant, Newborn
Enrollment
68,000 pts
Location
United States
Sponsor
NICHD Neonatal Research Networ
NCT06055608 Phase 2
Recruiting
Advancing Transplantation Outcomes in Children
Condition
Kidney Transplant
Enrollment
200 pts
Location
United States
Sponsor
National Institute of Allergy
NCT06059638 N/A
Recruiting
BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
Condition
Hypertension
Enrollment
316 pts
Location
United States, Australia, Belgium
Sponsor
Orchestra BioMed, Inc
NCT06393374 Phase 3
Recruiting
Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did ...
Condition
Triple-Negative Breast Cancer
Enrollment
1,530 pts
Location
United States, Argentina, Australia
Sponsor
Merck Sharp & Dohme LLC
NCT01524276 N/A
Recruiting
Product Surveillance Registry
Condition
Cardiac Rhythm Disorders
Enrollment
100,000 pts
Location
United States, Argentina, Australia
Sponsor
Medtronic
NCT07218926 Phase 3
Recruiting
A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastr...
Condition
Gastrointestinal Neoplasms
Enrollment
450 pts
Location
United States, Australia, Belgium
Sponsor
GlaxoSmithKline
NCT07507643 Phase 3
Recruiting
A Study of Methylprednisolone in People Having Liver Surgery
Condition
Hepatectomy
Enrollment
750 pts
Location
United States
Sponsor
Memorial Sloan Kettering Cance
NCT05778188 Phase 2
Recruiting
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary ...
Condition
Hypoxic-Ischemic Encephalopathy
Enrollment
70 pts
Location
United States
Sponsor
ReAlta Life Sciences, Inc.
NCT07052305 Phase 1
Recruiting
NT-I7 (Efineptakin Alfa), a Long-acting Human IL-7, Post-Axicabtagene Ciloleucel...
Condition
Large B-cell Lymphoma
Enrollment
24 pts
Location
United States
Sponsor
Washington University School o
NCT03551951 N/A
Recruiting
Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow
Condition
Non Small Cell Lung Cancer
Enrollment
320 pts
Location
United States
Sponsor
University of Missouri-Columbi
NCT06791837 N/A
Recruiting
Brain Blood Flow and Lactate in Non-obese and Obese Subjects
Condition
Diabetes
Enrollment
24 pts
Location
United States
Sponsor
University of Missouri-Columbi
NCT06619561 Phase 2
Recruiting
A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host ...
Condition
Chronic Graft-Versus-Host Disease (cGVHD)
Enrollment
48 pts
Location
United States
Sponsor
Deciphera Pharmaceuticals, LLC
NCT04420702 N/A
Recruiting
Diffusion Basis Spectrum Imaging of the Prostate
Condition
Prostate Cancer
Enrollment
500 pts
Location
United States
Sponsor
Washington University School o
NCT06152575 Phase 3
Recruiting
MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in P...
Condition
Multiple Myeloma
Enrollment
492 pts
Location
United States, Argentina, Australia
Sponsor
Pfizer
NCT06624670 Phase 3
Recruiting
A Study to Test Whether Spesolimab Helps People With a Skin Condition Called Pyo...
Condition
Pyoderma Gangrenosum
Enrollment
90 pts
Location
United States, Argentina, Australia
Sponsor
LEO Pharma
NCT07266805 Phase 3
Recruiting
Study of Oral Deucrictibant XR Tablet for Prophylaxis and Deucrictibant IR Capsu...
Condition
Acquired Angioedema Due to C1-Inhibitor Deficiency (AAE-C1-INH)
Enrollment
32 pts
Location
United States, Australia, Austria
Sponsor
Pharvaris Netherlands B.V.
NCT06672705 Phase 1
Recruiting
Epcoritamab for the Treatment of Relapsed or Refractory Post Transplant Lymphopr...
Condition
Diffuse Large B-Cell Lymphoma Post-Transplant Lymphoproliferative Disorder
Enrollment
26 pts
Location
United States
Sponsor
Timothy Voorhees
NCT07414836 Phase 1
Recruiting
A First-in-Human Study of BG-C0979 in Adults With Advanced Solid Tumors
Condition
Advanced Solid Tumor
Enrollment
84 pts
Location
United States, Australia, China
Sponsor
BeOne Medicines
NCT05076175 Phase 2, Phase 3
Recruiting
A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Mod...
Condition
Colitis, Ulcerative
Enrollment
120 pts
Location
United States, Australia, Belgium
Sponsor
Bristol-Myers Squibb
NCT05519475 Phase 2
Recruiting
A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Dise...
Condition
Metabolic Dysfunction-Associated SteatoHepatitis (MASH)
Enrollment
120 pts
Location
United States, Japan, Puerto Rico
Sponsor
Regeneron Pharmaceuticals
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology