State MO
Clinical Trials in Missouri
Missouri is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Missouri and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 261 actively recruiting studies with Missouri sites out of 261 registered in total. The busiest research areas in Missouri are Breast Cancer, Prostate Cancer, Solid Tumor. Leading sponsors running trials in the state include Washington University School of Medicine, National Cancer Institute (NCI), University of Missouri-Columbia. By stage, Missouri trials break down as Phase 1 (38), Phase 2 (69), Phase 3 (86), Phase 4 (8).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Missouri
Frequently Asked Questions — Clinical Trials in Missouri
How many clinical trials are currently recruiting in Missouri?
ClinicalMetric currently tracks 261 actively recruiting clinical trials with at least one location in Missouri. The total number of registered studies—including active but not currently enrolling trials—is 261. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Missouri?
Missouri hosts clinical trials across a broad range of medical conditions, including Breast Cancer, Prostate Cancer, Solid Tumor, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Missouri serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Missouri?
To join a clinical trial in Missouri, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Missouri maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Missouri
NCT06482567 N/A
Recruiting
Promoting Improved Functioning Among People Experiencing Stressful Situations
Condition
Acute Stress Reaction
Enrollment
450 pts
Location
United States
Sponsor
University of North Carolina,
NCT06616194 Phase 3
Recruiting
A Study to Learn About the Study Medicine Called Rimegepant in Adolescents With ...
Condition
Migraine
Enrollment
200 pts
Location
United States, Canada, China
Sponsor
Pfizer
NCT07415954 Phase 2
Recruiting
A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419...
Condition
Diabetes Mellitus, Type 2
Enrollment
270 pts
Location
United States, Croatia, Hungary
Sponsor
Novo Nordisk A/S
NCT06563895 Phase 3
Recruiting
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) S...
Condition
Amyloidosis
Enrollment
587 pts
Location
United States, Argentina, Australia
Sponsor
Eidos Therapeutics, a BridgeBi
NCT03507257 N/A
Recruiting
Longitudinal Early-onset Alzheimer's Disease Study Protocol
Condition
Early Onset Alzheimer Disease
Enrollment
850 pts
Location
United States, Argentina, Netherlands
Sponsor
Indiana University
NCT06895070 N/A
Recruiting
XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Ac...
Condition
Heart Transplant
Enrollment
60 pts
Location
United States
Sponsor
XVIVO Perfusion
NCT06623630 Phase 1
Recruiting
Lymphodepleting Total Body Irradiation (TBI) Plus Cyclophosphamide Prior to Cilt...
Condition
Multiple Myeloma
Enrollment
16 pts
Location
United States
Sponsor
Washington University School o
NCT07309445 N/A
Recruiting
A Study to Assess Real-World Use and Outcomes of TAR-200 for Participants With N...
Condition
Non-Muscle Invasive Bladder Neoplasms
Enrollment
150 pts
Location
United States
Sponsor
Janssen Research & Development
NCT05763251 N/A
Recruiting
Comparison of Uncomplicated Candidemia Therapy Duration in Children
Condition
Invasive Candidiasis
Enrollment
420 pts
Location
United States, Australia
Sponsor
Arkansas Children's Hospital R
NCT03821246 Phase 2
Recruiting
Neoadjuvant Atezolizumab-Based Combination Therapy in Men With Localized Prostat...
Condition
Prostate Adenocarcinoma
Enrollment
68 pts
Location
United States
Sponsor
David Oh
NCT06636786 Phase 2
Recruiting
Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Subli...
Condition
Acute Stress Reaction
Enrollment
180 pts
Location
United States
Sponsor
University of North Carolina,
NCT05803941 Phase 4
Recruiting
Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With ...
Condition
Prostate Cancer
Enrollment
700 pts
Location
United States, Austria, Belgium
Sponsor
Novartis Pharmaceuticals
NCT06289413 N/A
Recruiting
Autonomic Dysfunction in Patients Following Bariatric Surgery: The ADiPOSE Study
Condition
Autonomic Dysfunction
Enrollment
400 pts
Location
United States
Sponsor
Kansas City Heart Rhythm Resea
NCT02994433 Phase 1
Recruiting
NMDA Receptor Antagonist Nitrous Oxide Targets Affective Brain Circuits
Condition
Depressive Disorder, Major
Enrollment
60 pts
Location
United States
Sponsor
Washington University School o
NCT03526835 Phase 1, Phase 2
Recruiting
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
Condition
Advanced/Metastatic Solid Tumors
Enrollment
523 pts
Location
United States, Belgium, France
Sponsor
Merus B.V.
NCT06571474 N/A
Recruiting
Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity (ATM)
Condition
Obesity
Enrollment
60 pts
Location
United States
Sponsor
Bettina Mittendorfer
NCT07425015 N/A
Recruiting
Ambulatory Long Length URodynamics Evaluation
Condition
Urology
Enrollment
101 pts
Location
United States
Sponsor
Bright Uro
NCT05136196 Phase 2
Recruiting
BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Tr...
Condition
Clinical Stage III Cutaneous Melanoma AJCC v8
Enrollment
150 pts
Location
United States
Sponsor
National Cancer Institute (NCI
NCT07265479 Phase 3
Recruiting
A Study to Investigate Safety and Efficacy of Tapinarof Cream, 1% in Participant...
Condition
Atopic Dermatitis
Enrollment
180 pts
Location
United States, Canada
Sponsor
Organon and Co
NCT06960213 Phase 3
Recruiting
STOP-HAE: A Phase 3 Study of ADX-324 in HAE
Condition
Hereditary Angioedema
Enrollment
90 pts
Location
United States, Argentina, Australia
Sponsor
ADARx Pharmaceuticals, Inc.
NCT06101303 N/A
Recruiting
Endometriosis Pain
Condition
Pelvic Pain
Enrollment
120 pts
Location
United States
Sponsor
Washington University School o
NCT06402968 N/A
Recruiting
Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage
Condition
Intracerebral Hemorrhage
Enrollment
1,018 pts
Location
United States
Sponsor
Zeenat Qureshi Stroke Institut
NCT06279013 N/A
Recruiting
Comparing Telephone Symptom Monitoring Interventions for Managing Symptoms and P...
Condition
Hematopoietic and Lymphatic System Neoplasm
Enrollment
600 pts
Location
United States, Puerto Rico
Sponsor
NRG Oncology
NCT06172296 Phase 3
Recruiting
Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Tre...
Condition
Ganglioneuroblastoma, Nodular
Enrollment
478 pts
Location
United States, Australia, Canada
Sponsor
National Cancer Institute (NCI
NCT06350097 Phase 3
Recruiting
Phase III, Open-label Study of First-line Osimertinib With or Without Datopotama...
Condition
Non-small Cell Lung Cancer
Enrollment
582 pts
Location
United States, Australia, Brazil
Sponsor
AstraZeneca
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: July 2026 · Data Methodology