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Medical Condition

asthma

Total Trials

25

Recruiting Now

25

Trial Phases

Phase 2, Phase 4, Phase 3

Asthma clinical trials are increasingly stratified by phenotype β€” Type 2 high (eosinophilic, IgE-mediated) versus Type 2 low (neutrophilic or paucigranulocytic) β€” because this distinction predicts response to biologic therapies. The anti-IL-5, anti-IL-4/13, and anti-TSLP antibody classes have revolutionized severe asthma management, and trials now aim to achieve full remission rather than just symptom control.

Trials evaluate dupilumab combinations, tezepelumab (anti-TSLP) in Type 2 low asthma, itepekimab, biologic step-down strategies, and oral corticosteroid-sparing approaches. Digital inhalers with adherence monitoring are being validated as outcomes tools. Bronchial thermoplasty for severe non-biologic-responsive patients remains an active surgical comparator.

Frequently Asked Questions — asthma Clinical Trials

How many clinical trials are currently recruiting for asthma?

ClinicalMetric currently tracks 25 actively recruiting clinical trials for asthma, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 25. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for asthma?

asthma research spans Phase 2 (3 trials), Phase 3 (2 trials), Phase 4 (2 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a asthma clinical trial?

Eligibility criteria for asthma trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 2

3

Phase 3

2

Phase 4

2

Top Sponsors

Pfizer 1 trial

Indiana University 1 trial

Societa Italiana di Pneumologia 1 trial

Copenhagen University Hospital, Hvidovre 1 trial

University Medical Center Groningen 1 trial

Recruiting Clinical Trials

NCT06977581 Phase 2

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma

United States, Argen...

Acoustic Waveform Respiratory Evaluation

Indiana University

MANI Real-life Perspective Observatory

Societa Italiana di Pneumologi...

The Effect of Anti-IL17 on Airway Hyperresponsiveness and Resistance

Copenhagen University Hospital...

Inhaler Adherence and Inhalation Technique Assessed by a Smart Spacer in Patients with Severe Asthma on Biologics

University Medical Center Gron...

NCT03889743 Phase 4

Innovative Steroid Treatment to Reduce Asthma Development in Children After First-time Rhinovirus Induced Wheezing

Finland, Norway, Swe...

St. Olavs Hospital

Swiss Paediatric Airway Cohort

Austria, Switzerland

University of Bern

Intragastric Balloon in Obese Patients With Uncontrolled Asthma

University Hospital, Toulouse

Mitigating Chronic Respiratory Disease Through the Lens of Multi-Morbidity

University College, London

NCT06191315 Phase 3

Efficacy and Safety of Subcutaneous Dupilumab in Participants With Asthma/Asthmatic Wheeze Aged 2 to <6 Years (LIBERTY ASTHMA TREKIDS)

United States, Argen...

Multimodal Tongue-Pulse Information Fusion for Syndrome Diagnosis and Cohort Study in Children With Asthma

Shanghai Children's Medical Ce...

Residual Exacerbations With Mepolizumab

Laval University

NCT06152653 Phase 4

The Effects of Positive Airway Pressure on the Mucolytic Effects of NAC (TEAM)

University of California, San ...

Execise Intervention in Adult Severe Asthma

Helsinki University Central Ho...

TriMaximize: A Multicentre, Prospective, Non-interventional Trial in Asthma Patients

Chiesi Poland Sp. z o.o.

Aerobic Training Versus Behavioral Intervention to Increase Physical Activity in Patients With Asthma

University of Sao Paulo Genera...

Prospective Longitudinal Observational Research in Atopic Dermatitis

University of Zurich

To Assess the Management of Patients on Global Initiative of Asthma (GINA) Step 4 and 5 Treatment in Hong Kong

Chinese University of Hong Kon...

Assess Accuracy of Primary Care Asthma and COPD Diagnosis Using Oscillometry and FeNO vs Specialist Diagnosis

Argentina, Egypt, Me...

Use of fenoTRACK Device for Monitoring Changes of Fractional Exhaled Nitric Oxide (FeNO) in Uncontrolled Asthma Subjects and Controlled Asthma Subjects

NCT06829784 Phase 3

TQC2731 Clinical Trial for the Treatment of Severe Asthma With Injection

Shanghai Chia Tai Tianqing Pha...

NCT06216535 Phase 2

Escitalopram in Asthma Patients With Frequent Exacerbation

University of Texas Southweste...

Early Diagnosis and Treatment of Undiagnosed Asthma or COPD: THE UCAP 2 TRIAL

Ottawa Hospital Research Insti...

NCT02740868 Phase 2

Xenon-129 and Inert Fluorinated Gas Lung MRI: Study of Healthy Volunteers and Participants With Pulmonary Disease

The Hospital for Sick Children

Innate Immunity in Allergic Asthma

University of Central Florida

Related Conditions

copd (4) cystic fibrosis (2) wheezing (2) ciliary motility disorders (1) bronchiectasis (1) airway malacia (1) healthy control (1) mild asthma (1) moderate asthma (1) inflammation (1) cough (1) exercise induced bronchospasm (1)

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: April 2026 · Data Methodology