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Medical Condition

asthma

Total Trials

29

Recruiting Now

29

Trial Phases

Phase 2, Phase 3, Phase 4

Asthma clinical trials are increasingly stratified by phenotype β€” Type 2 high (eosinophilic, IgE-mediated) versus Type 2 low (neutrophilic or paucigranulocytic) β€” because this distinction predicts response to biologic therapies. The anti-IL-5, anti-IL-4/13, and anti-TSLP antibody classes have revolutionized severe asthma management, and trials now aim to achieve full remission rather than just symptom control.

Trials evaluate dupilumab combinations, tezepelumab (anti-TSLP) in Type 2 low asthma, itepekimab, biologic step-down strategies, and oral corticosteroid-sparing approaches. Digital inhalers with adherence monitoring are being validated as outcomes tools. Bronchial thermoplasty for severe non-biologic-responsive patients remains an active surgical comparator.

Frequently Asked Questions — asthma Clinical Trials

How many clinical trials are currently recruiting for asthma?

ClinicalMetric currently tracks 29 actively recruiting clinical trials for asthma, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 29. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for asthma?

asthma research spans Phase 2 (2 trials), Phase 3 (5 trials), Phase 4 (3 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a asthma clinical trial?

Eligibility criteria for asthma trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 2

2

Phase 3

5

Phase 4

3

Top Sponsors

Thammasat University 2 trials

Hospital Clinic of Barcelona 1 trial

Shanghai Children's Medical Center 1 trial

Commissariat A L'energie Atomique 1 trial

Johns Hopkins University 1 trial

Recruiting Clinical Trials

Effect of CPAP Treatment in Patients With Severe Uncontrolled Asthma: The ASTHMA-SLEEP Trial

Hospital Clinic of Barcelona

Multimodal Tongue-Pulse Information Fusion for Syndrome Diagnosis and Cohort Study in Children With Asthma

Shanghai Children's Medical Ce...

Evaluation of 3D Magnetic Resonance Spirometry: Comparison with Spirometry in Healthy Subjects and Patients with Respiratory Pathologies (asthma, COPD, Bilateral Lung Transplant)

Commissariat A L'energie Atomi...

NCT06273072 Phase 2

Metformin IN Asthma for Overweight and Obese Individuals (MINA)

Johns Hopkins University

Controls for Respiratory Diseases

Seoul National University Hosp...

Intragastric Balloon in Obese Patients With Uncontrolled Asthma

University Hospital, Toulouse

A Cohort for Inflammatory Respiratory Diseases: From Phenotyping to Personalised Medicine

Remission in Adults With Mild-to-moderate Asthma in Thailand

Thammasat University

NCT06307665 Phase 3

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma

United States, China...

MANI Real-life Perspective Observatory

Societa Italiana di Pneumologi...

NCT06323213 Phase 3

Efficacy and Safety Study of 610 in Patients With Severe Asthma

Sunshine Guojian Pharmaceutica...

Evaluation of High Dose Prednisolone Pharmacokinetics in the Acute and Chronic Setting

Imperial College London

NCT03889743 Phase 4

Innovative Steroid Treatment to Reduce Asthma Development in Children After First-time Rhinovirus Induced Wheezing

Finland, Norway, Swe...

St. Olavs Hospital

International Severe Asthma Registry_Hong Kong

Chinese University of Hong Kon...

Moving Towards Precision Medicine in United Airways Disease: Unraveling Inflammatory Patterns in Asthmatic Patients With or Without Nasal Polyps

Medical University of Vienna

NCT06570889 Phase 3

VItamin D in pregnanCy for prevenTion Of eaRlY Childhood Asthma

Professor Klaus Bønnelykke

Nutrition for Asthmatics

Pennington Biomedical Research...

Remote Patient Monitoring Solution for Chronic Respiratory Disease Management

SingHealth Polyclinics

BREATHE: An Efficacy-implementation Trial Among Black Adults With Uncontrolled Asthma

Columbia University

Chronic Obstructive Pulmonary Disease and Asthma in Workers at Navanakorn Industrial Zone, Thailand

Thammasat University

NCT05222529 Phase 2

Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Glycopyrronium (Bromide) in Children (6 to Less Than 12 Years) With Asthma

Bulgaria, Colombia, ...

Novartis Pharmaceuticals

NCT07228052 Phase 4

Giving Asthmatics Intramuscular Steroids for Preventing Return to the Emergency Department

Montefiore Medical Center

Improving Quality of Life for Teenagers With Asthma

University Hospital Southampto...

Role of "Asthma School" in Disease Management

Istituti Clinici Scientifici M...

NCT06829784 Phase 3

TQC2731 Clinical Trial for the Treatment of Severe Asthma With Injection

Shanghai Chia Tai Tianqing Pha...

Biomarkers of Response to Mepolizumab Treatment in Patients With Nasal Polyps With or Without Bronchial Asthma

Aristotle University Of Thessa...

NCT07166939 Phase 4

45th Multicenter Airway Research Collaboration

Massachusetts General Hospital

NCT06429475 Phase 3

Anti-Inflammatory Reliever South Africa

University of KwaZulu

InvEstigating oeStrogen Signalling and the Effect upoN the exTracelluar Matrix In pAtients With Obstructive Lung Disease

Guy's and St Thomas' NHS Found...

Related Conditions

copd (2) asthma chronic (2) chronic obstructive pulmonary disease (2) bronchiectasis (2) asthma control level (2) chronic rhinosinusitis with nasal polyps (2) asthma in children (2) asthma acute (2) obstructive sleep apnea (1) bos (1) overweight and obesity (1) idiopathic pulmonary fibrosis (1)

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology