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Medical Condition

asthma

Total Trials

22

Recruiting Now

22

Trial Phases

Phase 3, Phase 4

Asthma clinical trials are increasingly stratified by phenotype β€” Type 2 high (eosinophilic, IgE-mediated) versus Type 2 low (neutrophilic or paucigranulocytic) β€” because this distinction predicts response to biologic therapies. The anti-IL-5, anti-IL-4/13, and anti-TSLP antibody classes have revolutionized severe asthma management, and trials now aim to achieve full remission rather than just symptom control.

Trials evaluate dupilumab combinations, tezepelumab (anti-TSLP) in Type 2 low asthma, itepekimab, biologic step-down strategies, and oral corticosteroid-sparing approaches. Digital inhalers with adherence monitoring are being validated as outcomes tools. Bronchial thermoplasty for severe non-biologic-responsive patients remains an active surgical comparator.

Frequently Asked Questions — asthma Clinical Trials

How many clinical trials are currently recruiting for asthma?

ClinicalMetric currently tracks 22 actively recruiting clinical trials for asthma, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 22. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for asthma?

asthma research spans Phase 3 (5 trials), Phase 4 (2 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a asthma clinical trial?

Eligibility criteria for asthma trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 3

5

Phase 4

2

Top Sponsors

GlaxoSmithKline 3 trials

AstraZeneca 1 trial

Nantes University Hospital 1 trial

Kavita Parikh 1 trial

Cairo University 1 trial

Recruiting Clinical Trials

NCT06307665 Phase 3

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma

United States, China...

Study of the Impact of Exposure to Outdoor and Indoor Pollutants in Patients With Asthma

Nantes University Hospital

Hospital to Home Study: Trial to Optimize Transitions and Address Disparities in Asthma Care

Is There a Benefit From Addition of Physical Exercise to Diet Restriction/Limitation in PCOS Women With Asthma?

Cairo University

The Increase of Lung Capacity Using the Lung Master (Pulmonary Exerciser)

University of Nebraska

Effects of Salbutamol in Athletes and Implications for Screening and Sports

University of British Columbia

NCT07645248 Phase 3

A Study to Compare Safety of 4 Weeks Exposure to Propellants Hydrofluoroalkane 1,1-difluoroethane (HFA-152a) and HFA-1,1,1,2-tetrafluoroethane (134a)

United States, Argen...

GlaxoSmithKline

The Study About the Identification of Treatable Traits of Severe Asthma and the Construction of Personalized Treatment System

Beijing Chao Yang Hospital

NCT06570889 Phase 3

VItamin D in pregnanCy for prevenTion Of eaRlY Childhood Asthma

Professor Klaus Bønnelykke

NCT07228052 Phase 4

Giving Asthmatics Intramuscular Steroids for Preventing Return to the Emergency Department

Montefiore Medical Center

A Comparison of Diagnostic Testing Modalities in the Assessment of Asthma

Portsmouth Hospitals NHS Trust

Comparative Effects of Buteyko Versus Pilates Breathing Combined With McKenzie Neck Exercises on Lung Function and Chest Expansion in Asthmatic Patients With Forward Head Posture

Foundation University Islamaba...

NCT07782996 Phase 3

A Study to Investigate the Efficacy and Safety of GSK5784283 Compared With Placebo in Participants With Uncontrolled Asthma (PERSIST ASTHMA-2)

United States, Japan

GlaxoSmithKline

SMART@Home Feasibility Trial

Children's Hospital Medical Ce...

Community Connections Through Native Hawaiian Cultural Values to Strengthen Youth Resilience, Health, and Well-Being

Waianae Coast Comprehensive He...

NCT01225913 Phase 4

Mechanism(s) of Airflow Limitation During Exacerbation of Asthma

Gelb, Arthur F., M.D.

Prospective Multicentre Study on Symptoms in First-onset Bronchial Asthma in Children and Adolescents

Charles University, Czech Repu...

Mother-Infant Cohort Study in Malaysia and China

Universiti Putra Malaysia

NCT07456033 Phase 3

A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 Asthma

United States, Unite...

GlaxoSmithKline

Effects of Compression Stockings in Asthma Symptoms at Night

University Health Network, Tor...

Registry of Asthma Characterization and Recruitment 3 (RACR3)

National Institute of Allergy ...

Exploring the Lived Experience of Young Adults With Severe Asthma

Manchester University NHS Foun...

Related Conditions

asthma in children (3) dyspnea (2) eczema (2) wheezing (2) polycystic ovary syndrome (1) chronic obstructive pulmonary disease (1) healthy (1) effect of drug (1) respiratory tract infections (1) gastrointestinal infection (1) croup (1) allergy (1)

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology