Medical Condition

asthma

Total Trials

35

Recruiting Now

35

Trial Phases

Phase 2, Phase 3, Phase 4

Asthma clinical trials are increasingly stratified by phenotype — Type 2 high (eosinophilic, IgE-mediated) versus Type 2 low (neutrophilic or paucigranulocytic) — because this distinction predicts response to biologic therapies. The anti-IL-5, anti-IL-4/13, and anti-TSLP antibody classes have revolutionized severe asthma management, and trials now aim to achieve full remission rather than just symptom control.

Trials evaluate dupilumab combinations, tezepelumab (anti-TSLP) in Type 2 low asthma, itepekimab, biologic step-down strategies, and oral corticosteroid-sparing approaches. Digital inhalers with adherence monitoring are being validated as outcomes tools. Bronchial thermoplasty for severe non-biologic-responsive patients remains an active surgical comparator.

Frequently Asked Questions — asthma Clinical Trials

How many clinical trials are currently recruiting for asthma?

ClinicalMetric currently tracks 35 actively recruiting clinical trials for asthma, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 35. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for asthma?

asthma research spans Phase 1 (2 trials), Phase 2 (5 trials), Phase 3 (4 trials), Phase 4 (3 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a asthma clinical trial?

Eligibility criteria for asthma trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 1

Phase 2

Phase 3

Phase 4

Top Sponsors

AstraZeneca 4 trials

Chinese University of Hong Kong 2 trials

Sanofi 1 trial

The University of Texas Medical Branch, Galveston 1 trial

University of Nebraska 1 trial

asthma

Frequently Asked Questions — asthma Clinical Trials

Recruiting Clinical Trials

A Study Evaluating Disease Characteristics and Outcomes in Participants With Asthma in Routine Clinical Practice

Viral Mucosal Reprogramming

A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA)

The Increase of Lung Capacity Using the Lung Master (Pulmonary Exerciser)

Inhaler Trainer Efficacy Study

Individualizing Treatment for Asthma in Primary Care (Full Study)

Use of Biologics for Severe Asthma in Hong Kong

A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma

ReAl-woRld Evaluation of tEzepelumab for Chronic rhinoSinusitis With Nasal Polyps in Russia

To Assess the Management of Patients on Global Initiative of Asthma (GINA) Step 4 and 5 Treatment in Hong Kong

Innovative Steroid Treatment to Reduce Asthma Development in Children After First-time Rhinovirus Induced Wheezing

A Study to Test if a Fixed-Dose Combination of Fluticasone Propionate/Albuterol Sulfate is Effective in Preventing Asthma Exacerbations

Airway Remodeling and Rhinovirus in Asthmatics

Intragastric Balloon in Obese Patients With Uncontrolled Asthma

GRANITE: Airsupra Effectiveness in the Real World

Exploring the Utility of Hyperpolarized 129Xe MRI in Healthy Volunteers and Patients With Lung Disease

Expertise Asthma COPD Program with Digital Support

Effects of Compression Stockings in Asthma Symptoms at Night

Microglia Activation in Asthma

Escitalopram in Asthma Patients With Frequent Exacerbation

Effects of Balloon-blowing Exercises in 90/90 Bridge Position With a Ball on Pulmonary Function Among Asthmatic Patients

A Study to Evaluate the Safety and Tolerability of Multiple Dose of IBI3002 in Healthy and Asthmatic Participants

Mother-Infant Cohort Study in Malaysia and China

Inhaler Adherence and Inhalation Technique Assessed by a Smart Spacer in Patients with Severe Asthma on Biologics

A Phase 1, Randomized, Double-blind, Placebo-controlled Study Evaluating AMG 691 in Healthy Participants and Participants With Mild-to-Moderate Asthma

A Trial Evaluating Novel Technologies for the Diagnosis of Asthma The LUNG-TECH Trial

The Effects of Positive Airway Pressure on the Mucolytic Effects of NAC (TEAM)

Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Glycopyrronium (Bromide) in Children (6 to Less Than 12 Years) With Asthma

Pediatric Arm of DZL All Age Asthma Cohort

Expressions of Ezrin and Pip5k1α Proteins in Airway Smooth Muscle of Asthmatic Patients

TQC2731 Clinical Trial for the Treatment of Severe Asthma With Injection

Scalene Hold Relax Technique With Conventional Physical Therapy in Asthma

Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids

Effects of Salbutamol in Athletes and Implications for Screening and Sports

Metabolomics in the Diagnosis and Treatment of Asthma in Children