State IA
Clinical Trials in Iowa
Iowa is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Iowa and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 103 actively recruiting studies with Iowa sites out of 103 registered in total. The busiest research areas in Iowa are Breast Cancer, Metastatic Breast Cancer, Diabetes Mellitus, Type 2. Leading sponsors running trials in the state include National Cancer Institute (NCI), University of Iowa, Pfizer. By stage, Iowa trials break down as Phase 1 (17), Phase 2 (28), Phase 3 (37), Phase 4 (2).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Iowa
Breast Cancer (2)Metastatic Breast Cancer (2)Diabetes Mellitus, Type 2 (2)Stroke (2)Stage IV Renal Cell Cancer AJCC v8 (2)Alopecia Areata (2)Myeloma Multiple (1)Untreated, Unresectable, or Metastatic Colorectal Cancer (1)Acute Myeloid Leukemia (1)Acute Lymphoblastic Leukemia (1)Mixed Lineage Acute Leukemia (1)Mixed Phenotype Acute Leukemia (1)
Frequently Asked Questions — Clinical Trials in Iowa
How many clinical trials are currently recruiting in Iowa?
ClinicalMetric currently tracks 103 actively recruiting clinical trials with at least one location in Iowa. The total number of registered studies—including active but not currently enrolling trials—is 103. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Iowa?
Iowa hosts clinical trials across a broad range of medical conditions, including Breast Cancer, Metastatic Breast Cancer, Diabetes Mellitus, Type 2, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Iowa serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Iowa?
To join a clinical trial in Iowa, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Iowa maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Iowa
NCT07629440 Phase 3
Recruiting
A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.
Condition
Pneumococcal Disease
Enrollment
3,230 pts
Location
United States, Japan, Puerto Rico
Sponsor
Pfizer
NCT03373968 Phase 2, Phase 3
Recruiting
Givinostat in Duchenne's Muscular Dystrophy Long-term Safety and Tolerability St...
Condition
Duchenne Muscular Dystrophy
Enrollment
206 pts
Location
United States, Belgium, Canada
Sponsor
Italfarmaco
NCT07020117 Phase 1
Recruiting
A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors
Condition
Urothelial Carcinoma Bladder
Enrollment
150 pts
Location
United States
Sponsor
Aktis Oncology, Inc.
NCT07287150 Phase 2
Recruiting
A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-...
Condition
Metastatic Castration-Resistant Prostate Cancer
Enrollment
100 pts
Location
United States, Australia, Brazil
Sponsor
Hoffmann-La Roche
NCT05004493 N/A
Recruiting
Biorepository and Registry for Plasma Exchange Patients
Condition
Antibody-mediated Rejection
Enrollment
200 pts
Location
United States
Sponsor
Charles M Knudson
NCT07146906 Phase 2
Recruiting
A Study to Assess the Effects of Zigakibart on IgA Nephropathy.
Condition
Immunoglobulin A Nephropathy (IgAN)
Enrollment
32 pts
Location
United States, Brazil, China
Sponsor
Novartis Pharmaceuticals
NCT06030063 N/A
Recruiting
The Society for Obstetric Anesthesia and Perinatology Research Network General A...
Condition
Cesarean Delivery
Enrollment
5,000 pts
Location
United States, Canada
Sponsor
Yale University
NCT00009633 N/A
Recruiting
Follow-up Visit of High Risk Infants
Condition
Infant, Newborn
Enrollment
68,000 pts
Location
United States
Sponsor
NICHD Neonatal Research Networ
NCT04649242 Phase 3
Recruiting
Randomized Study in Children and Adolescents With Migraine: Acute Treatment
Condition
Pediatric Migraine
Enrollment
2,100 pts
Location
United States, Canada, China
Sponsor
Pfizer
NCT07082738 Phase 2
Recruiting
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Ve...
Condition
Chronic Obstructive Pulmonary Disease (COPD)
Enrollment
987 pts
Location
United States, Argentina, Australia
Sponsor
AstraZeneca
NCT06750094 Phase 3
Recruiting
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in P...
Condition
Colorectal Neoplasms
Enrollment
700 pts
Location
United States, Australia, Belgium
Sponsor
Janssen Research & Development
NCT07047144 Phase 2
Recruiting
A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years ...
Condition
Spinal Muscular Atrophy
Enrollment
52 pts
Location
United States, Belgium, France
Sponsor
Scholar Rock, Inc.
NCT07144150 N/A
Recruiting
EVERO Drug-coated Balloon (DCB) Randomized Trial
Condition
Peripheral Vascular Disease
Enrollment
410 pts
Location
United States
Sponsor
Cook Research Incorporated
NCT07715669 EARLY_Phase 1
Recruiting
Antidepressant Therapy for Improved Blood Vessel Health After Preeclampsia
Condition
Preeclampsia
Enrollment
40 pts
Location
United States
Sponsor
Anna Stanhewicz, PhD
NCT06213649 Phase 3
Recruiting
Parasitic Ulcer Treatment Trial
Condition
Acanthamoeba Keratitis
Enrollment
232 pts
Location
United States, Brazil, India
Sponsor
Jeremy Keenan, MD, MPH
NCT07630974 Phase 1, Phase 2
Recruiting
A Study of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refr...
Condition
Malignant Neoplasm
Enrollment
134 pts
Location
United States, Australia, Belgium
Sponsor
Merck Sharp & Dohme LLC
NCT06994806 Phase 1
Recruiting
A Study to Investigate the Safety and Efficacy of KQB168 as Monotherapy and in C...
Condition
Solid Tumor Malignancies
Enrollment
84 pts
Location
United States
Sponsor
Kumquat Biosciences Inc.
NCT06475989 Phase 3
Recruiting
Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer
Condition
Refractory Differentiated Thyroid Gland Carcinoma
Enrollment
264 pts
Location
United States
Sponsor
ECOG-ACRIN Cancer Research Gro
NCT04817618 Phase 3
Recruiting
Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.
Condition
C3G
Enrollment
98 pts
Location
United States, Argentina, Belgium
Sponsor
Novartis Pharmaceuticals
NCT06831110 N/A
Recruiting
Aquagenic Wrinkling Prediction
Condition
Aquagenic Wrinkling of Palms
Enrollment
2,000 pts
Location
United States
Sponsor
University of Iowa
NCT06328608 Phase 2, Phase 3
Recruiting
A Study to Learn About the Safety and Effects of the Study Drug PRX-102 in Child...
Condition
Fabry Disease
Enrollment
22 pts
Location
United States, Austria, France
Sponsor
Chiesi Farmaceutici S.p.A.
NCT07450547 Phase 2
Recruiting
Phase 2 Study to Assess the Safety and Efficacy of ANG003
Condition
Exocrine Pancreatic Insufficiency (EPI)
Enrollment
113 pts
Location
United States
Sponsor
Anagram Therapeutics, Inc.
NCT07472426 N/A
Recruiting
Effects of Creatine Supplementation on Cognitive Measures and Markers of Acute K...
Condition
Acute Kidney Injury
Enrollment
20 pts
Location
United States
Sponsor
University of Northern Iowa
NCT07406633 Phase 2
Recruiting
KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIS...
Condition
GIST - Gastrointestinal Stromal Tumor
Enrollment
46 pts
Location
United States
Sponsor
Kumquat Biosciences Inc.
NCT05338697 N/A
Recruiting
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future...
Condition
Stroke
Enrollment
657 pts
Location
United States
Sponsor
Yale University
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology