State IA
Clinical Trials in Iowa
Iowa is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Iowa and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 118 actively recruiting studies with Iowa sites out of 118 registered in total. The busiest research areas in Iowa are Acute Myeloid Leukemia, Breast Cancer, COPD. Leading sponsors running trials in the state include SWOG Cancer Research Network, National Cancer Institute (NCI), Alliance for Clinical Trials in Oncology. By stage, Iowa trials break down as Phase 1 (17), Phase 2 (30), Phase 3 (44), Phase 4 (3).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Iowa
Acute Myeloid Leukemia (4)Breast Cancer (3)COPD (2)SLE (Systemic Lupus) (2)Metastatic Gastric Adenocarcinoma (2)Colorectal Cancer (2)Peripheral Arterial Disease (2)Intracranial Meningioma (2)Macular Degeneration (2)Stage III Pancreatic Cancer AJCC v8 (2)Stage IV Pancreatic Cancer AJCC v8 (2)Lung Cancer (2)
Frequently Asked Questions — Clinical Trials in Iowa
How many clinical trials are currently recruiting in Iowa?
ClinicalMetric currently tracks 118 actively recruiting clinical trials with at least one location in Iowa. The total number of registered studies—including active but not currently enrolling trials—is 118. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Iowa?
Iowa hosts clinical trials across a broad range of medical conditions, including Acute Myeloid Leukemia, Breast Cancer, COPD, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Iowa serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Iowa?
To join a clinical trial in Iowa, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Iowa maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Iowa
NCT05624996 Phase 3
Recruiting
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for...
Condition
Locally Advanced Lung Non-Small Cell Carcinoma
Enrollment
474 pts
Location
United States, Canada
Sponsor
NRG Oncology
NCT06096259 Phase 2
Recruiting
Preventing Injured Knees From osteoArthritis: Severity Outcomes
Condition
Osteoarthritis, Knee
Enrollment
512 pts
Location
United States
Sponsor
Brigham and Women's Hospital
NCT06822426 Phase 3
Recruiting
Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodst...
Condition
Central Line Associated Blood Stream Infections (CLABSI)
Enrollment
200 pts
Location
United States, Turkey (Türkiye)
Sponsor
CorMedix Therapeutics
NCT03942081 N/A
Recruiting
Diabetic Foot Ulcer Imaging- Study 2
Condition
Foot Ulcer
Enrollment
500 pts
Location
United States
Sponsor
Linnea Polgreen
NCT04065399 Phase 1, Phase 2
Recruiting
A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rea...
Condition
Acute Myeloid Leukemia
Enrollment
447 pts
Location
United States, Australia, Canada
Sponsor
Syndax Pharmaceuticals
NCT04871542 N/A
Recruiting
Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors
Condition
Malignant Solid Neoplasm
Enrollment
2,062 pts
Location
United States, Chile, Guam
Sponsor
SWOG Cancer Research Network
NCT06127316 N/A
Recruiting
The Effects of Heel Distraction Height on Foot Loading With Carbon Fiber Custom ...
Condition
Traumatic Lower Limb Injury
Enrollment
20 pts
Location
United States
Sponsor
University of Iowa
NCT07165132 Phase 1
Recruiting
Study of RYZ401 in Subjects With Solid Tumors Expressing SSTRs.
Condition
GEP-NET
Enrollment
104 pts
Location
United States, Canada
Sponsor
RayzeBio, Inc.
NCT07326709 Phase 3
Recruiting
A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Part...
Condition
Huntington Disease
Enrollment
770 pts
Location
United States, Argentina, Australia
Sponsor
Novartis Pharmaceuticals
NCT07510087 N/A
Recruiting
Glaucoma Related Quality of Life
Condition
Glaucoma
Enrollment
5,000 pts
Location
United States
Sponsor
Marc Toeteberg-Harms
NCT05006716 Phase 1, Phase 2
Recruiting
A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participant...
Condition
B-cell Malignancy
Enrollment
645 pts
Location
United States, Australia, Brazil
Sponsor
BeOne Medicines
NCT02523014 Phase 2
Recruiting
Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating ...
Condition
Intracranial Meningioma
Enrollment
124 pts
Location
United States
Sponsor
Alliance for Clinical Trials i
NCT03150693 Phase 3
Recruiting
Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With N...
Condition
B Acute Lymphoblastic Leukemia
Enrollment
303 pts
Location
United States, Canada
Sponsor
Alliance for Clinical Trials i
NCT06779773 N/A
Recruiting
A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice ...
Condition
Geographic Atrophy
Enrollment
500 pts
Location
United States
Sponsor
Astellas Pharma Global Develop
NCT06998940 Phase 3
Recruiting
Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Adva...
Condition
Locally Advanced Pancreatic Adenocarcinoma
Enrollment
94 pts
Location
United States
Sponsor
SWOG Cancer Research Network
NCT04715178 N/A
Recruiting
Beat Childhood Cancer Specimen Banking and Data Registry
Condition
Pediatric Cancer
Enrollment
1,000 pts
Location
United States
Sponsor
Giselle Sholler
NCT03180268 Phase 3
Recruiting
Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade...
Condition
Grade 2 Meningioma
Enrollment
163 pts
Location
United States, Canada, India
Sponsor
NRG Oncology
NCT07091617 N/A
Recruiting
Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing ...
Condition
Miscellaneous Neoplasm, Nos
Enrollment
535 pts
Location
United States
Sponsor
Alliance for Clinical Trials i
NCT03954899 N/A
Recruiting
Disease Modifying Potential of 5mg of Melatonin on Cognition and Brain Health in...
Condition
Mild Cognitive Impairment
Enrollment
230 pts
Location
United States
Sponsor
Natalie Denburg
NCT06673589 N/A
Recruiting
Brain-to-brain Synchrony in Ss With Different Levels of Social Interaction
Condition
Social Dynamics
Enrollment
30 pts
Location
United States
Sponsor
Maharishi International Univer
NCT06533176 N/A
Recruiting
Real-time Personalized Brain State-dependent TMS After Stroke
Condition
Stroke
Enrollment
37 pts
Location
United States
Sponsor
Sara Hussain
NCT06519955 Phase 2, Phase 3
Recruiting
Can PLIA Reduce Early Post-operative Pain After PAO Surgery?
Condition
Hip Dysplasia
Enrollment
120 pts
Location
United States
Sponsor
Michael C Willey
NCT07144150 N/A
Recruiting
EVERO Drug-coated Balloon (DCB) Randomized Trial
Condition
Peripheral Vascular Disease
Enrollment
410 pts
Location
United States
Sponsor
Cook Research Incorporated
NCT06655246 Phase 1
Recruiting
A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gas...
Condition
Gastrointestinal Stromal Tumor (GIST)
Enrollment
157 pts
Location
United States
Sponsor
Kura Oncology, Inc.
NCT05677490 Phase 3
Recruiting
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanc...
Condition
Advanced Esophageal Adenocarcinoma
Enrollment
382 pts
Location
United States, Puerto Rico
Sponsor
Alliance for Clinical Trials i
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology