State IA
Clinical Trials in Iowa
Iowa is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Iowa and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 118 actively recruiting studies with Iowa sites out of 118 registered in total. The busiest research areas in Iowa are Acute Myeloid Leukemia, Breast Cancer, COPD. Leading sponsors running trials in the state include SWOG Cancer Research Network, National Cancer Institute (NCI), Alliance for Clinical Trials in Oncology. By stage, Iowa trials break down as Phase 1 (17), Phase 2 (30), Phase 3 (44), Phase 4 (3).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Iowa
Acute Myeloid Leukemia (4)Breast Cancer (3)COPD (2)SLE (Systemic Lupus) (2)Metastatic Gastric Adenocarcinoma (2)Colorectal Cancer (2)Peripheral Arterial Disease (2)Intracranial Meningioma (2)Macular Degeneration (2)Stage III Pancreatic Cancer AJCC v8 (2)Stage IV Pancreatic Cancer AJCC v8 (2)Lung Cancer (2)
Frequently Asked Questions — Clinical Trials in Iowa
How many clinical trials are currently recruiting in Iowa?
ClinicalMetric currently tracks 118 actively recruiting clinical trials with at least one location in Iowa. The total number of registered studies—including active but not currently enrolling trials—is 118. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Iowa?
Iowa hosts clinical trials across a broad range of medical conditions, including Acute Myeloid Leukemia, Breast Cancer, COPD, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Iowa serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Iowa?
To join a clinical trial in Iowa, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Iowa maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Iowa
NCT04239573 N/A
Recruiting
Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Assoc...
Condition
Pancreatic Neoplasm
Enrollment
770 pts
Location
United States, Canada, Puerto Rico
Sponsor
ECOG-ACRIN Cancer Research Gro
NCT04202341 N/A
Recruiting
Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion...
Condition
Generalized Myasthenia Gravis
Enrollment
500 pts
Location
United States, Austria, Canada
Sponsor
Alexion Pharmaceuticals, Inc.
NCT04398628 N/A
Recruiting
ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders
Condition
Hematologic Disorder
Enrollment
3,000 pts
Location
United States
Sponsor
American Thrombosis and Hemost
NCT07018869 Phase 3
Recruiting
Evaluating Whether an Educational Website Called Current Together After Cancer (...
Condition
Colorectal Cancer Stage II
Enrollment
1,057 pts
Location
United States, Guam, Puerto Rico
Sponsor
SWOG Cancer Research Network
NCT06013865 Phase 4
Recruiting
Empagliflozin Treatment in Kidney Transplant Recipients
Condition
Kidney Transplant
Enrollment
264 pts
Location
United States
Sponsor
VA Office of Research and Deve
NCT06382155 Phase 2
Recruiting
A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature
Condition
Idiopathic Short Stature
Enrollment
100 pts
Location
United States, Australia, France
Sponsor
BioMarin Pharmaceutical
NCT06317649 Phase 2
Recruiting
Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute M...
Condition
Acute Myeloid Leukemia
Enrollment
147 pts
Location
United States, Puerto Rico
Sponsor
National Cancer Institute (NCI
NCT05677971 Phase 3
Recruiting
Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People ...
Condition
Alpha1-Antitrypsin Deficiency
Enrollment
160 pts
Location
United States, Australia, Austria
Sponsor
Takeda
NCT05939414 Phase 3
Recruiting
An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Obse...
Condition
Oligometastatic Prostate Cancer (OMPC)
Enrollment
450 pts
Location
United States, Argentina, Australia
Sponsor
Novartis Pharmaceuticals
NCT05983432 Phase 1
Recruiting
Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lun...
Condition
Non Small Cell Lung Cancer
Enrollment
470 pts
Location
United States, France, Italy
Sponsor
SystImmune Inc.
NCT05204888 N/A
Recruiting
myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home
Condition
COPD
Enrollment
642 pts
Location
United States, Canada
Sponsor
Temple University
NCT07784725 Phase 3
Recruiting
A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Over...
Condition
Obesity or Overweight
Enrollment
2,500 pts
Location
United States, Argentina, Australia
Sponsor
AstraZeneca
NCT05467891 Phase 2
Recruiting
Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurr...
Condition
Locoregional Recurrence
Enrollment
200 pts
Location
United States
Sponsor
Oana Danciu
NCT07391774 Phase 3
Recruiting
Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy ...
Condition
Anatomic Stage II Breast Cancer AJCC v8
Enrollment
1,978 pts
Location
United States, Puerto Rico
Sponsor
National Cancer Institute (NCI
NCT06831110 N/A
Recruiting
Aquagenic Wrinkling Prediction
Condition
Aquagenic Wrinkling of Palms
Enrollment
2,000 pts
Location
United States
Sponsor
University of Iowa
NCT06264180 Phase 3
Recruiting
VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on A...
Condition
Advanced Melanoma
Enrollment
400 pts
Location
United States, France, Germany
Sponsor
Replimune, Inc.
NCT07765927 N/A
Recruiting
Exercise Oncology Clinic Pilot Feasibility Trial
Condition
Breast Cancer
Enrollment
30 pts
Location
United States
Sponsor
Jess S. Gorzelitz
NCT06318169 Phase 3
Recruiting
A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With ...
Condition
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis
Enrollment
1,350 pts
Location
United States, Argentina, Australia
Sponsor
89bio, Inc.
NCT01297400 Phase 2
Recruiting
Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burn...
Condition
Burns
Enrollment
60 pts
Location
United States, Mexico
Sponsor
Skingenix, Inc.
NCT04817618 Phase 3
Recruiting
Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.
Condition
C3G
Enrollment
98 pts
Location
United States, Argentina, Belgium
Sponsor
Novartis Pharmaceuticals
NCT06422923 Phase 1, Phase 2
Recruiting
A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral...
Condition
Epilepsy, Temporal Lobe
Enrollment
10 pts
Location
United States
Sponsor
Neurona Therapeutics
NCT05932680 Phase 2
Recruiting
Limited-duration Teclistamab
Condition
Myeloma Multiple
Enrollment
75 pts
Location
United States
Sponsor
Abramson Cancer Center at Penn
NCT06194929 Phase 1, Phase 2
Recruiting
Defactinib and Avutometinib, With or Without Encorafenib, for the Treatment of P...
Condition
Cutaneous Melanoma
Enrollment
33 pts
Location
United States
Sponsor
University of Utah
NCT06544499 Phase 3
Recruiting
A Study to Assess the Efficacy and Safety of Efgartigimod IV in Adult Participan...
Condition
Primary Immune Thrombocytopenia (ITP)
Enrollment
69 pts
Location
United States, Austria, Bulgaria
Sponsor
argenx
NCT07662109 Phase 3
Recruiting
A Phase III Study to Investigate the Efficacy and Safety of the Combination of E...
Condition
Type 2 Diabetes Mellitus
Enrollment
2,000 pts
Location
United States, Argentina, Brazil
Sponsor
AstraZeneca
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology