State IA
Clinical Trials in Iowa
Iowa is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Iowa and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 107 actively recruiting studies with Iowa sites out of 107 registered in total. The busiest research areas in Iowa are Breast Cancer, Metastatic Breast Cancer, Stage IVB Prostate Cancer AJCC v8. Leading sponsors running trials in the state include National Cancer Institute (NCI), AstraZeneca, Alliance for Clinical Trials in Oncology. By stage, Iowa trials break down as Phase 1 (14), Phase 2 (29), Phase 3 (36), Phase 4 (4).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Iowa
Breast Cancer (4)Metastatic Breast Cancer (3)Stage IVB Prostate Cancer AJCC v8 (2)Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 (2)Locally Recurrent Head and Neck Squamous Cell Carcinoma (2)Locally Recurrent Hypopharyngeal Squamous Cell Carcinoma (2)Locally Recurrent Laryngeal Squamous Cell Carcinoma (2)Locally Recurrent Oral Cavity Squamous Cell Carcinoma (2)Locally Recurrent Oropharyngeal Squamous Cell Carcinoma (2)Stage III Laryngeal Cancer AJCC v8 (2)Stage III Lip and Oral Cavity Cancer AJCC v8 (2)Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 (2)
Frequently Asked Questions — Clinical Trials in Iowa
How many clinical trials are currently recruiting in Iowa?
ClinicalMetric currently tracks 107 actively recruiting clinical trials with at least one location in Iowa. The total number of registered studies—including active but not currently enrolling trials—is 107. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Iowa?
Iowa hosts clinical trials across a broad range of medical conditions, including Breast Cancer, Metastatic Breast Cancer, Stage IVB Prostate Cancer AJCC v8, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Iowa serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Iowa?
To join a clinical trial in Iowa, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Iowa maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Iowa
NCT06324357 Phase 1, Phase 2
Recruiting
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in...
Condition
Metastatic Breast Cancer
Enrollment
768 pts
Location
United States, Belgium, China
Sponsor
Boehringer Ingelheim
NCT07085767 Phase 3
Recruiting
Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/...
Condition
Breast Cancer
Enrollment
1,000 pts
Location
United States, Australia, Austria
Sponsor
Olema Pharmaceuticals, Inc.
NCT03420339 Phase 4
Recruiting
Stimulant Effects on Disruptive Behavior
Condition
Attention Deficit Hyperactivity Disorder
Enrollment
10 pts
Location
United States
Sponsor
Matthew J O'Brien, PhD, BCBA-D
NCT06855277 Phase 3
Recruiting
Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With P...
Condition
Prostate Cancer
Enrollment
940 pts
Location
United States, Australia, Brazil
Sponsor
Novartis Pharmaceuticals
NCT07206225 Phase 1
Recruiting
A Study to Learn About the Study Medicine PF-08052667 in People With Bladder Can...
Condition
Non-muscle Invasive Bladder Cancer
Enrollment
294 pts
Location
United States, France, Israel
Sponsor
Pfizer
NCT06916806 Phase 1
Recruiting
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynam...
Condition
Systemic Lupus Erythematosus
Enrollment
72 pts
Location
United States, Canada, China
Sponsor
AstraZeneca
NCT06492733 N/A
Recruiting
FastWire REvascularisation of Extremities, (For LOWer Limbs) - FREEFLOW
Condition
Chronic Total Occlusion of Artery of the Extremities
Enrollment
65 pts
Location
United States
Sponsor
Versono Medical Ltd
NCT04800484 N/A
Recruiting
The Effects of AFO Heel Height and Stiffness on Gait
Condition
Musculoskeletal Injury
Enrollment
40 pts
Location
United States
Sponsor
University of Iowa
NCT07195734 Phase 2
Recruiting
Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery...
Condition
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Enrollment
180 pts
Location
United States
Sponsor
National Cancer Institute (NCI
NCT07404332 Phase 1
Recruiting
5-Azacitidine Plus PD-1/PD-L1 Inhibitor With PD-1/PD-L1 Refractory Tumors
Condition
Solid Tumor
Enrollment
35 pts
Location
United States
Sponsor
Mohammed Milhem
NCT05508906 Phase 1
Recruiting
Phase 1b Study of OP-1250 (Palazestrant) in Combination With Ribociclib, Alpelis...
Condition
Metastatic Breast Cancer
Enrollment
190 pts
Location
United States, Australia
Sponsor
Olema Pharmaceuticals, Inc.
NCT00196742 N/A
Recruiting
Fabry Disease Registry & Pregnancy Sub-registry
Condition
Fabry Disease
Enrollment
9,000 pts
Location
United States, Argentina, Australia
Sponsor
Genzyme, a Sanofi Company
NCT05180773 Phase 4
Recruiting
Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy
Condition
Peripartum Cardiomyopathy, Postpartum
Enrollment
250 pts
Location
United States
Sponsor
Dennis M. McNamara, MD, MS
NCT06592924 Phase 3
Recruiting
Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Ca...
Condition
Prostate Cancer (Adenocarcinoma)
Enrollment
830 pts
Location
United States, Canada, Mexico
Sponsor
Canadian Cancer Trials Group
NCT06454344 N/A
Recruiting
The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs ...
Condition
Adverse Childhood Experiences
Enrollment
70 pts
Location
United States
Sponsor
Nathaniel Jenkins
NCT07143019 N/A
Recruiting
The Use of p48/64 MW HPC Flow Modulation Device in the Treatment of Wide-necked ...
Condition
Hemorrhagic Stroke
Enrollment
214 pts
Location
United States
Sponsor
phenox Inc.
NCT04852887 Phase 3
Recruiting
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, O...
Condition
Stage I Breast Cancer
Enrollment
1,670 pts
Location
United States, Canada, Hong Kong
Sponsor
NRG Oncology
NCT05896189 N/A
Recruiting
Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Surv...
Condition
Breast Cancer
Enrollment
386 pts
Location
United States, Puerto Rico
Sponsor
NRG Oncology
NCT07321652 Phase 3
Recruiting
Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment ...
Condition
Chronic Lymphocytic Leukemia
Enrollment
466 pts
Location
United States
Sponsor
Alliance for Clinical Trials i
NCT06297226 Phase 2
Recruiting
Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Ther...
Condition
Multiple Myeloma
Enrollment
230 pts
Location
United States, Australia, Canada
Sponsor
Juno Therapeutics, Inc., a Bri
NCT04609046 Phase 1
Recruiting
Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Pr...
Condition
Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System
Enrollment
47 pts
Location
United States
Sponsor
National Cancer Institute (NCI
NCT06096259 Phase 2
Recruiting
Preventing Injured Knees From osteoArthritis: Severity Outcomes
Condition
Osteoarthritis, Knee
Enrollment
512 pts
Location
United States
Sponsor
Brigham and Women's Hospital
NCT00674388 N/A
Recruiting
The Pediatric Anesthesia Quality Improvement Project
Condition
Surgery
Enrollment
5,000,000 pts
Location
United States
Sponsor
The Society for Pediatric Anes
NCT02523014 Phase 2
Recruiting
Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating ...
Condition
Intracranial Meningioma
Enrollment
124 pts
Location
United States
Sponsor
Alliance for Clinical Trials i
NCT00063063 N/A
Recruiting
Generic Database of Very Low Birth Weight Infants
Condition
Infant, Newborn
Enrollment
80,000 pts
Location
United States
Sponsor
NICHD Neonatal Research Networ
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: July 2026 · Data Methodology