State IA
Clinical Trials in Iowa
Iowa is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Iowa and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 107 actively recruiting studies with Iowa sites out of 107 registered in total. The busiest research areas in Iowa are Breast Cancer, Metastatic Breast Cancer, Stage IVB Prostate Cancer AJCC v8. Leading sponsors running trials in the state include National Cancer Institute (NCI), AstraZeneca, Alliance for Clinical Trials in Oncology. By stage, Iowa trials break down as Phase 1 (14), Phase 2 (29), Phase 3 (36), Phase 4 (4).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Iowa
Breast Cancer (4)Metastatic Breast Cancer (3)Stage IVB Prostate Cancer AJCC v8 (2)Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 (2)Locally Recurrent Head and Neck Squamous Cell Carcinoma (2)Locally Recurrent Hypopharyngeal Squamous Cell Carcinoma (2)Locally Recurrent Laryngeal Squamous Cell Carcinoma (2)Locally Recurrent Oral Cavity Squamous Cell Carcinoma (2)Locally Recurrent Oropharyngeal Squamous Cell Carcinoma (2)Stage III Laryngeal Cancer AJCC v8 (2)Stage III Lip and Oral Cavity Cancer AJCC v8 (2)Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 (2)
Frequently Asked Questions — Clinical Trials in Iowa
How many clinical trials are currently recruiting in Iowa?
ClinicalMetric currently tracks 107 actively recruiting clinical trials with at least one location in Iowa. The total number of registered studies—including active but not currently enrolling trials—is 107. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Iowa?
Iowa hosts clinical trials across a broad range of medical conditions, including Breast Cancer, Metastatic Breast Cancer, Stage IVB Prostate Cancer AJCC v8, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Iowa serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Iowa?
To join a clinical trial in Iowa, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Iowa maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Iowa
NCT06721962 Phase 1, Phase 2
Recruiting
Treatment of Moderate to Severe Refractory Crohn's Disease
Condition
Crohns Disease
Enrollment
39 pts
Location
United States
Sponsor
Tr1X, Inc.
NCT04853251 Phase 4
Recruiting
A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age...
Condition
Neovascular Age-related Macular Degeneration
Enrollment
188 pts
Location
United States
Sponsor
Genentech, Inc.
NCT07200830 Phase 3
Recruiting
Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA ...
Condition
Metastatic Castration-Resistant Prostate Carcinoma
Enrollment
1,524 pts
Location
United States
Sponsor
Alliance for Clinical Trials i
NCT07225127 N/A
Recruiting
Comparison of Intravesical Therapy and Surgery as Treatment Options for Bladder ...
Condition
Bladder Cancer
Enrollment
408 pts
Location
United States
Sponsor
University of Washington
NCT06779773 N/A
Recruiting
A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice ...
Condition
Geographic Atrophy
Enrollment
500 pts
Location
United States
Sponsor
Astellas Pharma Global Develop
NCT05004493 N/A
Recruiting
Biorepository and Registry for Plasma Exchange Patients
Condition
Antibody-mediated Rejection
Enrollment
200 pts
Location
United States
Sponsor
Charles M Knudson
NCT02734277 N/A
Recruiting
Type 1 Diabetes Extension Study
Condition
Type 1 Diabetes Mellitus
Enrollment
111 pts
Location
United States
Sponsor
National Institute of Allergy
NCT04671667 Phase 2
Recruiting
Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itse...
Condition
Recurrent Head and Neck Squamous Cell Carcinoma
Enrollment
188 pts
Location
United States
Sponsor
National Cancer Institute (NCI
NCT07109219 Phase 1, Phase 2
Recruiting
Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Partici...
Condition
B-cell Acute Lymphoblastic Leukemia (B-ALL)
Enrollment
83 pts
Location
United States, Australia, Canada
Sponsor
AstraZeneca
NCT07391657 Phase 3
Recruiting
A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antig...
Condition
Relapsed Refractory Multiple Myeloma
Enrollment
508 pts
Location
United States, Australia, Brazil
Sponsor
AstraZeneca
NCT05136196 Phase 2
Recruiting
BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Tr...
Condition
Clinical Stage III Cutaneous Melanoma AJCC v8
Enrollment
150 pts
Location
United States
Sponsor
National Cancer Institute (NCI
NCT05775523 N/A
Recruiting
A Post-Authorisation Safety Study (PASS) of Patients Treated With Lonapegsomatro...
Condition
Growth Hormone Deficiency
Enrollment
500 pts
Location
United States
Sponsor
Ascendis Pharma Endocrinology
NCT06107374 Phase 2
Recruiting
Imaging Advanced NSCLC Patients Undergoing PD-1/PD-L1 Directed Therapy Using [18...
Condition
Advanced Non Small Cell Lung Cancer
Enrollment
20 pts
Location
United States
Sponsor
CellSight Technologies, Inc.
NCT06352788 N/A
Recruiting
From Opinion to Evidence: Multi-site Evaluation of Custom Dynamic Orthosis Best ...
Condition
Foot Injury
Enrollment
35 pts
Location
United States
Sponsor
Jason Wilken
NCT06172296 Phase 3
Recruiting
Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Tre...
Condition
Ganglioneuroblastoma, Nodular
Enrollment
478 pts
Location
United States, Australia, Canada
Sponsor
National Cancer Institute (NCI
NCT04994756 N/A
Recruiting
Stroke Thrombectomy and Aneurysm Registry
Condition
Stroke
Enrollment
40,000 pts
Location
United States, Canada, Germany
Sponsor
Medical University of South Ca
NCT06749457 Phase 1, Phase 2
Recruiting
A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase...
Condition
Staphylococcus Aureus
Enrollment
231 pts
Location
United States
Sponsor
AstraZeneca
NCT04566328 Phase 3
Recruiting
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Mu...
Condition
Plasma Cell Myeloma
Enrollment
1,450 pts
Location
United States, Puerto Rico
Sponsor
ECOG-ACRIN Cancer Research Gro
NCT05147792 N/A
Recruiting
The CONFORM Pivotal Trial
Condition
Atrial Fibrillation
Enrollment
1,600 pts
Location
United States, Czechia, France
Sponsor
Conformal Medical, Inc
NCT06655246 Phase 1
Recruiting
A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gas...
Condition
Gastrointestinal Stromal Tumor (GIST)
Enrollment
157 pts
Location
United States
Sponsor
Kura Oncology, Inc.
NCT06679855 Phase 3
Recruiting
Milrinone for Prevention of Post-ligation Cardiac Syndrome Trial
Condition
Post-ligation Cardiac Syndrome
Enrollment
316 pts
Location
United States
Sponsor
NICHD Neonatal Research Networ
NCT06664710 N/A
Recruiting
Evaluation of the Automated Integration of a Robotics and ECochG System for Use ...
Condition
Hearing Loss, Sensorineural
Enrollment
10 pts
Location
United States
Sponsor
iotaMotion, Inc.
NCT06337318 Phase 3
Recruiting
Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor ...
Condition
Classic Follicular Lymphoma
Enrollment
600 pts
Location
United States
Sponsor
National Cancer Institute (NCI
NCT06524882 Phase 3
Recruiting
Dichoptic Treatment for Amblyopia in Children 8 to 12 Years of Age
Condition
Amblyopia
Enrollment
252 pts
Location
United States
Sponsor
Jaeb Center for Health Researc
NCT07198074 Phase 3
Recruiting
Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Ca...
Condition
Advanced Endometrial Carcinoma
Enrollment
255 pts
Location
United States
Sponsor
National Cancer Institute (NCI
Page 1 of 5 — 107 trials total
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: July 2026 · Data Methodology