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covid 19

Total Trials
19
Recruiting Now
19
Trial Phases
Phase 2, Phase 4

COVID-19 trials proliferated rapidly during the pandemic and now encompass antiviral treatments, long COVID management, and ongoing vaccine refinements for new variants. The platform trial model — where multiple interventions share a single control arm — was pioneered at scale for COVID-19 (RECOVERY, ACTIV-3, SOLIDARITY) and has since been adopted across other disease areas.

Active trials address long COVID (fatigue, cognitive impairment, autonomic dysfunction), antiviral combinations for high-risk outpatients, mucosal vaccines for variant-resistant immunity, and mechanistic studies into post-COVID organ damage. Paxlovid rebound, nirmatrelvir resistance, and immunocompromised host management are current investigation areas.

Frequently Asked Questions — covid 19 Clinical Trials

How many clinical trials are currently recruiting for covid 19?
ClinicalMetric currently tracks 19 actively recruiting clinical trials for covid 19, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 19. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for covid 19?
covid 19 research spans Phase 2 (3 trials), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a covid 19 clinical trial?
Eligibility criteria for covid 19 trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 2
3
Phase 4
1
Top Sponsors
University of Chicago 2 trials
Euresist Network GEIE 2 trials
Centre Hospitalier Régional d'Orléans 1 trial
Columbia University 1 trial
IRCCS Burlo Garofolo 1 trial

Recruiting Clinical Trials

NCT06825819
Recruiting

Dysbiosis & Long COVID

Enrollment
400 pts
Location
United States
Sponsor
University of Chicago
View Trial →
NCT07085611
Recruiting

Neutralizing Power of Serum Antibodies - 2

Enrollment
30 pts
Location
France
Sponsor
Centre Hospitalier Régional d'...
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NCT05467930
Recruiting

CU-COMMITS: COVID-19 Care in Black and Latino Communities and Households. Clinical and Molecular Outcomes of SARS-CoV-2

Enrollment
1,000 pts
Location
United States
Sponsor
Columbia University
View Trial →
NCT06309186
Recruiting

Empowerment and Burnout of Midwives at the End of Health Emergency From COVID-19

Enrollment
64 pts
Location
Italy
Sponsor
IRCCS Burlo Garofolo
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NCT06159283 Phase 2
Recruiting

Intravenous Immunoglobulin Replacement Therapy for Persistent COVID-19 in Patients With B-cell Impairment

Enrollment
58 pts
Location
South Korea
Sponsor
Jaehoon Ko
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NCT06968442
Recruiting

The Role of Obesity in Severe COVID-19 Pathophysiology

Enrollment
60 pts
Location
Netherlands
Sponsor
Franciscus Gasthuis
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NCT05531773
Recruiting

Post COVID-19 Condition

Enrollment
2,300 pts
Location
Germany, Italy, Lith...
Sponsor
Euresist Network GEIE
View Trial →
NCT05268523
Recruiting

Self-Management Interventions for Long COVID-19

Enrollment
270 pts
Location
Canada
Sponsor
Toronto Rehabilitation Institu...
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NCT04477889
Recruiting

Methodist Health System COVID-19 Patient Registry

Enrollment
500 pts
Location
United States
Sponsor
Methodist Health System
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NCT05463380
Recruiting

Hospitalised COVID-19 Patients Cohort Study in the EuCARE Project

Enrollment
22,000 pts
Location
Germany, Italy, Keny...
Sponsor
Euresist Network GEIE
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NCT06168019
Recruiting

Influenza & COVID-19 Obstetric and Perinatal Epidemiology Study in India

Enrollment
10,000 pts
Location
United States, India
Sponsor
Boston University
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NCT07128095
Recruiting

COVID-19 Health Adjustments in Nutrition, General Wellness, and Exercise

Enrollment
100 pts
Location
United States
Sponsor
Indiana University
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NCT05886816 Phase 2
Recruiting

Mitoquinone/Mitoquinol Mesylate as Oral and Safe Postexposure Prophylaxis for Covid-19

Enrollment
112 pts
Location
United States
Sponsor
University of Texas Southweste...
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NCT05191381
Recruiting

Immune Modulation by Exosomes in COVID-19

Enrollment
40 pts
Location
Germany
Sponsor
University of Ulm
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NCT05539482
Recruiting

Community-Based Health Education Programs for the Early Detection of, and Vaccination Against, COVID-19 and the Adoption of Self-Protective Measures of Hong Kong Residents

Enrollment
1,200 pts
Location
Hong Kong
Sponsor
The Hong Kong Polytechnic Univ...
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NCT06008860 Phase 4
Recruiting

A Pilot Clinical Evaluation of Astepro® Nasal Spray for Management of Early SARS-CoV-2 Infection

Enrollment
280 pts
Location
United States
Sponsor
University of Chicago
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NCT04427566 Phase 2
Recruiting

Low Dose Whole Lung Radiation Therapy for Patients With COVID-19 and Respiratory Compromise

Enrollment
24 pts
Location
United States
Sponsor
Ohio State University Comprehe...
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NCT05796505
Recruiting

Addressing Vaccine Acceptance in Carceral Settings Through Community Engagement

Enrollment
37,122 pts
Location
United States
Sponsor
Yale University
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NCT05078905
Recruiting

Vaccine Responses to SARS-CoV-2 and Other Emerging Infectious Diseases

Enrollment
1,200 pts
Location
United States
Sponsor
National Institute of Allergy ...
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology