State MO
Clinical Trials in Missouri
Missouri is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Missouri and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 286 actively recruiting studies with Missouri sites out of 286 registered in total. The busiest research areas in Missouri are Obesity, Carcinoma, Non-Small-Cell Lung, Multiple Myeloma. Leading sponsors running trials in the state include Washington University School of Medicine, National Cancer Institute (NCI), AstraZeneca. By stage, Missouri trials break down as Phase 1 (40), Phase 2 (81), Phase 3 (88), Phase 4 (6).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Missouri
Obesity (6)Carcinoma, Non-Small-Cell Lung (5)Multiple Myeloma (4)Myelodysplastic Syndromes (4)Advanced Solid Tumor (4)Alzheimer Disease (4)Heart Failure (4)Cardiovascular Diseases (4)Smoking Cessation (4)Acute Myeloid Leukemia (4)B Acute Lymphoblastic Leukemia (3)Pancreatic Ductal Adenocarcinoma (3)
Frequently Asked Questions — Clinical Trials in Missouri
How many clinical trials are currently recruiting in Missouri?
ClinicalMetric currently tracks 286 actively recruiting clinical trials with at least one location in Missouri. The total number of registered studies—including active but not currently enrolling trials—is 286. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Missouri?
Missouri hosts clinical trials across a broad range of medical conditions, including Obesity, Carcinoma, Non-Small-Cell Lung, Multiple Myeloma, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Missouri serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Missouri?
To join a clinical trial in Missouri, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Missouri maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Missouri
NCT02402244 N/A
Recruiting
Project: Every Child for Younger Patients With Cancer
Condition
Adrenal Gland Pheochromocytoma
Enrollment
75,000 pts
Location
United States, Australia, Canada
Sponsor
Children's Oncology Group
NCT06996652 Phase 2
Recruiting
An Exploratory Study of the Potential for Rational Immune System Manipulation to...
Condition
REM Sleep Behavior Disorder
Enrollment
108 pts
Location
United States, Canada
Sponsor
Yale University
NCT07073547 Phase 1
Recruiting
A Phase I, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, C...
Condition
Multiple Myeloma
Enrollment
40 pts
Location
United States
Sponsor
AstraZeneca
NCT06950385 Phase 3
Recruiting
Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis
Condition
Familial Adenomatous Polyposis (FAP)
Enrollment
168 pts
Location
United States, Denmark, Germany
Sponsor
Rapamycin Holdings Inc.
NCT06820463 Phase 2
Recruiting
A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Teli...
Condition
Metastatic Colorectal Cancer
Enrollment
390 pts
Location
United States, Australia, Austria
Sponsor
AbbVie
NCT07646678 Phase 2, Phase 3
Recruiting
A Study of TAK-360 in People With Narcolepsy or Idiopathic Hypersomnia
Condition
Idiopathic Hypersomnia
Enrollment
500 pts
Location
United States, China, Japan
Sponsor
Takeda
NCT06867185 N/A
Recruiting
Evaluating Therapeutic Electrical Stimulation to Improve Nerve Healing After Sur...
Condition
Digital Nerve Injury
Enrollment
60 pts
Location
United States
Sponsor
Checkpoint Surgical Inc.
NCT05570448 N/A
Recruiting
Anti-Reflux Endoscopic TX Using APC (AREA) in GERD Patients: (The AREA Study)
Condition
Gastro Esophageal Reflux
Enrollment
36 pts
Location
United States
Sponsor
Midwest Veterans' Biomedical R
NCT03150693 Phase 3
Recruiting
Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With N...
Condition
B Acute Lymphoblastic Leukemia
Enrollment
303 pts
Location
United States, Canada
Sponsor
Alliance for Clinical Trials i
NCT06531499 Phase 1
Recruiting
A Study of Radiation Dosimetry, Safety, and Tolerability of Extended Lutetium (1...
Condition
Metastatic Castration-Resistant Prostate Cancer
Enrollment
106 pts
Location
United States, Germany, Netherlands
Sponsor
Novartis Pharmaceuticals
NCT07033494 Phase 2
Recruiting
A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-00...
Condition
Early Alzheimer's Disease
Enrollment
340 pts
Location
United States, Argentina, Australia
Sponsor
Merck Sharp & Dohme LLC
NCT02074839 Phase 1
Recruiting
Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malign...
Condition
Relapsed or Refractory Acute Myeloid Leukemia (AML)
Enrollment
291 pts
Location
United States, France
Sponsor
Institut de Recherches Interna
NCT06772493 N/A
Recruiting
ViewFlex X ICE First-in-Human Study
Condition
Cardiac Arrhythmias
Enrollment
500 pts
Location
United States
Sponsor
Abbott Medical Devices
NCT07287644 Phase 2, Phase 3
Recruiting
A Study Evaluating BFB759 in Moderate to Severe Hidradenitis Suppurativa
Condition
Hidradenitis Suppurativa (HS)
Enrollment
210 pts
Location
United States, Bulgaria, Canada
Sponsor
Bluefin Biomedicine, Inc.
NCT05320198 Phase 1, Phase 2
Recruiting
Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplas...
Condition
Myelofibrosis; Anemia
Enrollment
150 pts
Location
United States, Australia
Sponsor
Disc Medicine, Inc
NCT06926634 Phase 2
Recruiting
Zanzalintinib Maintenance in Patients With High Grade Neuroendocrine Neoplasms (...
Condition
High Grade Neuroendocrine Neoplasms
Enrollment
32 pts
Location
United States
Sponsor
Washington University School o
NCT06524830 Phase 2
Recruiting
A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, C...
Condition
Treatment Resistant Depression
Enrollment
142 pts
Location
United States, Australia, Canada
Sponsor
atai Therapeutics, Inc.
NCT07020221 Phase 1, Phase 2
Recruiting
A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors
Condition
Pancreatic Ductal Adenocarcinoma
Enrollment
295 pts
Location
United States, Australia
Sponsor
Verastem, Inc.
NCT07764978 Phase 3
Recruiting
Study of AZD0120 in Newly Diagnosed Multiple Myeloma Ineligible for ASCT
Condition
Newly Diagnosed Multiple Myeloma
Enrollment
750 pts
Location
United States, Australia, Brazil
Sponsor
AstraZeneca
NCT06433115 N/A
Recruiting
Effects of Lean Beef Consumption on Cardiometabolic Health and Gut Microbiome
Condition
Diet Intervention
Enrollment
90 pts
Location
United States
Sponsor
University of Missouri-Columbi
NCT06312176 Phase 3
Recruiting
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combinatio...
Condition
Breast Neoplasms
Enrollment
1,200 pts
Location
United States, Argentina, Australia
Sponsor
Merck Sharp & Dohme LLC
NCT07448038 Phase 2
Recruiting
A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokin...
Condition
Atherosclerosis
Enrollment
162 pts
Location
United States, Canada
Sponsor
Genentech, Inc.
NCT05483010 Phase 2
Recruiting
Statins in Patients With Clonal Cytopenia of Undetermined Significance (CCUS) an...
Condition
Clonal Cytopenia of Undetermined Significance
Enrollment
16 pts
Location
United States
Sponsor
Washington University School o
NCT06548360 Phase 3
Recruiting
A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Pa...
Condition
NonSegmental Vitiligo
Enrollment
180 pts
Location
United States, Canada
Sponsor
Incyte Corporation
NCT05111015 N/A
Recruiting
Tracking Results of Ablations to Combat AF Registry Generation 2
Condition
Atrial Fibrillation
Enrollment
10,000 pts
Location
United States, Austria, Canada
Sponsor
AtriCure, Inc.
Page 1 of 12 — 286 trials total
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology