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Recruiting NCT05555069

The Impact of Menthol Flavoring on Switching in Adult Menthol Smokers

Trial Parameters

Condition Smoking Reduction
Sponsor Nikki Nollen, PhD, MA
Study Type INTERVENTIONAL
Phase N/A
Enrollment 800
Sex ALL
Min Age 21 Years
Max Age N/A
Start Date 2022-11-08
Completion 2026-12-31
Interventions
Menthol-flavored electronic cigaretteTobacco-flavored electronic cigarette

Brief Summary

This study will compare the efficacy of menthol-flavored versus tobacco-flavored 4th generation nicotine salt-based pod-system e-cigarettes in facilitating a switch from combustible cigarettes to e-cigarettes in adult menthol smokers.

Eligibility Criteria

Inclusion Criteria: * ≥ 21 years of age * Smoke ≥ 5 cigarettes per day (CPD) * Smoke menthol cigarettes for ≥ 6 months * Verified smoker (CO \>5ppm) * Functioning telephone * Interested in switching to E-cigarettes Exclusion Criteria: * Interested in quitting smoking * Use of other tobacco products in past 30 days (i.e. cigarillos, cigars, hookah, smokeless tobacco, pipes) * E-cigarette use on ≥ 4 of the past 30 days * Uncontrolled hypertension: BP ≥ 180(systolic) or ≥ 105 (diastolic) * Use of smoking cessation pharmacotherapy in the month prior to enrollment * Pregnant, contemplating getting pregnant, or breastfeeding * Plans to move from Kansas City during the treatment and follow-up phase * Another household member enrolled in the study

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