Medical Condition

stroke

Total Trials

20

Recruiting Now

20

Trial Phases

Phase 4

Stroke trials address both acute treatment (revascularization within hours of onset) and long-term secondary prevention, with rehabilitation science emerging as a distinct research priority. Advances in thrombectomy techniques have dramatically improved outcomes for large vessel occlusion strokes, driving trials to push the treatment window from 6 to 24 hours in selected patients.

Current research includes tenecteplase vs alteplase for thrombolysis, thrombectomy for medium vessel occlusions, neuroprotective agents, factor XIa inhibitors for secondary prevention with lower bleeding risk, and telerehabilitation using robotics and brain-computer interfaces. Trials in wake-up stroke and unknown time-of-onset have expanded using MRI mismatch criteria.

Frequently Asked Questions — stroke Clinical Trials

How many clinical trials are currently recruiting for stroke?

ClinicalMetric currently tracks 20 actively recruiting clinical trials for stroke, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 20. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for stroke?

stroke research spans Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a stroke clinical trial?

Eligibility criteria for stroke trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 4

Top Sponsors

Riphah International University 2 trials

University of Pittsburgh 1 trial

University Hospital, Ghent 1 trial

Shirley Ryan AbilityLab 1 trial

Kırıkkale University 1 trial

stroke

Frequently Asked Questions — stroke Clinical Trials

Recruiting Clinical Trials

Effects of Action Observation Therapy Based on Virtual Reality for Upper Extremity Rehabilitation in Stroke

An Augmented Reality Based System for Neglect Detection, Assessment, and Rehabilitation

Comparing the Ceriter Stride One, a Pressure-sensitive Smart Insole, With Gait Parameters Measured on the GRAIL in Neurological Populations

Error-enhanced Learning & Recovery in 2 & 3 Dimensions

Spinal Straightness, Posture And Balance, Physical Performance And Energy Consumption In Individuals With Stroke

Standardized Goal-Directed vs. Self-Directed Valsalva Maneuver for the Assessment of Patent Foramen Ovale

Efficacy of Trans-spinal Magnetic Stimulation on Functional Mobility in Chronic Stroke Patients

What is the Optimal Antithrombotic Strategy in Patients With Atrial Fibrillation Undergoing PCI?

New Interactive Sensor-home-based Hand Training to Improve Dexterity

Real-time Personalized Brain State-dependent TMS After Stroke

Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)

ECoG BMI for Motor and Speech Control

Study on the Correlation Mechanism and Application of Genetic Susceptibility, Hemoglobin Adaptation Changes, and Extubation Success Rate in Stroke Patients With Tracheotomy at Different Altitudes

Effects of Task-Based Mirror Therapy for Post-stroke Shoulder-Hand Syndrome

Constraint-Induced Movement Therapy for Adults Post-Stroke With Mild Upper Extremity Impairment

Promoting Community Reintegration for Young Adults With Stroke

Robotic Rehabilitation of the Upper Limb in Subacute Stroke

Virtual Reality Software for Patients With Stroke

The Effect of Targeting the Plantaris Muscle-tendon in Surgical Correction of Ankle Equinus in Children

Genetic Variants of Annexin A2 and Cryptogenic Stroke