NCT07624630 Walking and Thinking - Brain Activity During Complex Walking in Stroke
| NCT ID | NCT07624630 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Karolinska Institutet |
| Condition | Stroke |
| Study Type | OBSERVATIONAL |
| Enrollment | 50 participants |
| Start Date | 2026-08-01 |
| Primary Completion | 2027-07-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 50 participants in total. It began in 2026-08-01 with a primary completion date of 2027-07-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Everyday life requires individuals to function in complex environments and perform tasks that involve the integration of motor and cognitive abilities. However, stroke often leads to impairments in motor-cognitive interaction, which can negatively affect mobility, balance, attention, and the ability to live independently. Although motor-cognitive performance has been identified as an important rehabilitation target after stroke, limited knowledge exists regarding the underlying brain function associated with these difficulties and how rehabilitation and exercise interventions can best address them. Improving treatment for motor-cognitive difficulties after stroke, such as dual-task walking and navigation, remains a major challenge. An important step is developing assessment methods that accurately capture these impairments in ecologically valid settings that reflect real-world mobility demands. The investigators therefore aim to explore brain function during complex walking after stroke by investigating motor-cognitive performance and its neural correlates during three walking conditions: dual-task walking, navigation, and a combination of both. Non-invasive measures of brain activity using functional near-infrared spectroscopy (fNIRS) together with advanced real-time gait analysis will be used to better understand how stroke affects motor-cognitive functioning during complex walking tasks.
Eligibility Criteria
Inclusion Criteria: * 18 years or older * with a stroke ≥6 months confirmed by a clinical diagnosis * with the ability to walk with or without a walking aid for ≥ 5 min Exclusion Criteria: * Individuals post stroke with cognitive impairment * severe neglect * global aphasia affecting the ability to provide written informed consent * severe perceptual problems or severe freezing of gait
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07624630 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Stroke. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07624630 currently recruiting?
Yes, NCT07624630 is actively recruiting participants. Contact the research team at compliance@ki.se for enrollment information.
Where is the NCT07624630 trial being conducted?
This trial is being conducted at Solna, Sweden.
Who is sponsoring the NCT07624630 clinical trial?
NCT07624630 is sponsored by Karolinska Institutet. The trial plans to enroll 50 participants.
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