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traumatic brain injury

Total Trials
20
Recruiting Now
20
Trial Phases
Phase 4

ClinicalMetric tracks all active clinical trials for traumatic brain injury sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — traumatic brain injury Clinical Trials

How many clinical trials are currently recruiting for traumatic brain injury?
ClinicalMetric currently tracks 20 actively recruiting clinical trials for traumatic brain injury, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 20. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for traumatic brain injury?
traumatic brain injury research spans Phase 4 (2 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a traumatic brain injury clinical trial?
Eligibility criteria for traumatic brain injury trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 4
2
Top Sponsors
Shanghai 6th People's Hospital 2 trials
Centre Hospitalier Princesse Grace 1 trial
Bangladesh Medical University 1 trial
Georgetown University 1 trial
Istituti Clinici Scientifici Maugeri SpA 1 trial

Recruiting Clinical Trials

NCT05885529
Recruiting
Glial Fibrillary Acidic Protein (GFAP) and Ubiquitin Carboxy-terminal Hydrolase L1 (UCH-L1) to Exclude Lesions Linked to Significant Traumatic Brain Injuries
Enrollment
1,500 pts
Location
France, Monaco
Sponsor
Centre Hospitalier Princesse G...
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NCT07739264
Recruiting
ZEPU-SGI1PLUS Hand Training Study (ZEPUSGI1RCT)
Enrollment
36 pts
Location
Bangladesh
Sponsor
Bangladesh Medical University
View Trial →
NCT07635329
Recruiting
Home-based Vision Rehabilitation Guided by Brain Imaging
Enrollment
100 pts
Location
United States
Sponsor
Georgetown University
View Trial →
NCT06241482
Recruiting
Safety and Efficacy of Enhanced Recovery After Surgery in Neurocritical Care
Enrollment
80 pts
Location
China
Sponsor
Shanghai 6th People's Hospital
View Trial →
NCT06920784
Recruiting
Prismatic Adaptation in Cognitive Rehabilitation
Enrollment
50 pts
Location
Italy
Sponsor
Istituti Clinici Scientifici M...
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NCT06697808
Recruiting
Cranial Ultrasound for Point of Care Intracranial Pathology Detection in Pediatrics
Enrollment
169 pts
Location
United States
Sponsor
Wake Forest University Health ...
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NCT06177509
Recruiting
Effect of Graded Aerobic Exercise in Mild Traumatic Brain Injury
Enrollment
72 pts
Location
Norway
Sponsor
Sunnaas Rehabilitation Hospita...
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NCT07624825
Recruiting
Emotional Awareness Therapy Study
Enrollment
48 pts
Location
United States
Sponsor
Hackensack Meridian Health
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NCT07225101 Phase 4
Recruiting
Evaluation of the Efficacy of STRATAFIX for Neurosurgical Cranial and Spine Procedures
Enrollment
160 pts
Location
United States
Sponsor
University of Michigan
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NCT06127459
Recruiting
Virtual Reality in Rehabilitation of Executive Functions in Children With Mild or Moderate Traumatic Brain Injury
Enrollment
44 pts
Location
Finland
Sponsor
Merja Nikula
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NCT03399929
Recruiting
Traumatic Brain Injury and Stroke Long Term Outcome
Enrollment
240 pts
Location
United States
Sponsor
Centre for Neuro Skills
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NCT07120373
Recruiting
An Exploration of Sleep Disturbance and Outcomes in TBI (SLEEP-TBI)
Enrollment
180 pts
Location
United Kingdom
Sponsor
University of Nottingham
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NCT06311604
Recruiting
Evaluation of the Safety of Inhaled Sedation With Isoflurane in Head Trauma Patients
Enrollment
30 pts
Location
France
Sponsor
University Hospital, Grenoble
View Trial →
NCT05095857 Phase 4
Recruiting
The Anaesthetic Ketamine as Treatment for Patients With Severe Acute Brain Injury
Enrollment
400 pts
Location
Denmark
Sponsor
Rigshospitalet, Denmark
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NCT06465290
Recruiting
Promoting Neuroplastic Changes of Patients With TBI
Enrollment
100 pts
Location
United States
Sponsor
University of Maryland, Baltim...
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NCT02592291
Recruiting
Mobile Health Self-Management and Support System for Chronic and Complex Health Conditions
Enrollment
160 pts
Location
United States
Sponsor
University of Pittsburgh
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NCT06766435
Recruiting
Evaluation of the Abbott i-STAT TBI Biomarker Test
Enrollment
450 pts
Location
United States
Sponsor
Icahn School of Medicine at Mo...
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NCT05533060
Recruiting
Clinical and Molecular Biological Data Collection and Analysis in Patients With TBI
Enrollment
200 pts
Location
China
Sponsor
Shanghai 6th People's Hospital
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NCT07473505
Recruiting
Integrative Bilateral Cervical Sympathetic Blocks for Trauma-Related Symptoms in Special Operations Veterans: A Prospective Case Series
Enrollment
75 pts
Location
United States
Sponsor
Reset Medical and Wellness Cen...
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NCT05277519
Recruiting
Neuroplasticity After Proprioceptive Rehabiliation
Enrollment
56 pts
Location
France
Sponsor
Institut National de la Santé ...
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Related Conditions

stroke (4) upper limb motor dysfunction (1) incomplete spinal cord injury (1) upper limb orthopedic trauma (1) visual field defect (1) hemianopia homonymous (1) quadrantanopia (1) cortical blindness (1) visual field defect peripheral (1) visual field loss (1) brain tumor (1) neurocritical care (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology