NCT07725211 Task-Oriented Training Versus High-Intensity Gait Training in People With Chronic Stroke
| NCT ID | NCT07725211 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Istanbul University - Cerrahpasa |
| Condition | Stroke |
| Study Type | INTERVENTIONAL |
| Enrollment | 45 participants |
| Start Date | 2026-08-15 |
| Primary Completion | 2026-12-15 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 45 participants in total. It began in 2026-08-15 with a primary completion date of 2026-12-15.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this study is to compare the effects of high-repetition task-oriented training and high-intensity gait training on walking capacity and functional mobility in individuals with chronic stroke. Forty-five participants will be randomly assigned to one of three groups: (1) neurodevelopmental treatment (NDT) alone, (2) NDT combined with high-repetition task-oriented training, or (3) NDT combined with high-intensity gait training. All participants will receive treatment 3 days per week for 8 weeks (24 sessions in total). Walking capacity (6-Minute Walk Test) and functional mobility (Timed Up and Go Test, modified Dynamic Gait Index, 10-Meter Walk Test) will be assessed before and after the intervention by an assessor blinded to group allocation. The study hypothesizes that adding structured, intensity-based training approaches to conventional NDT will lead to greater improvements in walking capacity than NDT alone.
Eligibility Criteria
Inclusion Criteria: * Diagnosis of first-ever unilateral stroke (ischemic or hemorrhagic) confirmed by clinical and/or radiological findings * Time since stroke onset of at least 6 months (chronic phase) * Age between 18 and 75 years * Ability to walk at least 10 meters independently, with or without an assistive device * Functional Ambulation Category (FAC) score of 3 or higher * Sufficient cognitive ability to understand and follow instructions (Mini-Mental State Examination score ≥ 24) * Willingness to participate and provision of written informed consent Exclusion Criteria: * Recurrent stroke or bilateral hemispheric involvement * Unstable cardiovascular disease or other medical conditions contraindicating high-intensity exercise * Severe lower extremity spasticity interfering with gait training (Modified Ashworth Scale score \> 3) * Orthopedic, rheumatological, or other neurological conditions affecting gait * Severe visual or vestibular impairment * Severe aphasia or cognitive impairment preventing participation in training or assessments * Participation in another structured rehabilitation or exercise program during the study period * Botulinum toxin injection to the lower extremity within the last 6 months
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07725211 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Stroke. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07725211 currently recruiting?
Yes, NCT07725211 is actively recruiting participants. Contact the research team at zireke@gmail.com for enrollment information.
Where is the NCT07725211 trial being conducted?
This trial is being conducted at Bingoel, Turkey (Türkiye).
Who is sponsoring the NCT07725211 clinical trial?
NCT07725211 is sponsored by Istanbul University - Cerrahpasa. The trial plans to enroll 45 participants.
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