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Recruiting EARLY_Phase 1 NCT07011173

Assistance Delivery and Muscle Coordination

Trial Parameters

Condition Stroke
Sponsor The Catholic University of America
Study Type INTERVENTIONAL
Phase EARLY_Phase 1
Enrollment 30
Sex ALL
Min Age 20 Years
Max Age 80 Years
Start Date 2024-11-21
Completion 2025-12-31
Interventions
Exotendon assistanceEnd-effector assistance

Brief Summary

The experiment will be conducted with 15 chronic stroke survivors and 15 control subjects. Subjects will perform extension movements of the index finger of their more-impaired (stroke) or nondominant (control) hand under two different assistance types: end-effector assistance and exotendon assistance. For each assistance type, unassisted movements will be performed before and after the assistance. Subjects will be randomly assigned into two groups (A and B), who will receive the assistance in a different order. The finger movements and muscle activation patterns will be recorded during movements.

Eligibility Criteria

Inclusion Criteria for stroke survivors: * Age: 18 - 70 years old * First-ever unilateral cortical stroke with resultant hemiparesis at least 6 months prior to the experimental testing * Fugl-Meyer Upper Extremity Section 31 - 55 Exclusion Criteria for both stroke and control: * Presence of concurrent severe medical illness * Pain in hand or arm with movements * Loss of voluntary control of fingers and thumb * Inability to provide informed consent * Musculoskeletal injuries (e.g., fracture) or medical complications (e.g., severe cardiovascular disease).

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