NCT07066137 Motor Learning in Health and Movement Disorders: Role of Physical Activity and Advanced Devices
| NCT ID | NCT07066137 |
| Status | Recruiting |
| Phase | — |
| Sponsor | IRCCS Centro Neurolesi Bonino Pulejo |
| Condition | Healthy Individuals (Controls) |
| Study Type | INTERVENTIONAL |
| Enrollment | 150 participants |
| Start Date | 2024-05-05 |
| Primary Completion | 2028-12-06 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 150 participants in total. It began in 2024-05-05 with a primary completion date of 2028-12-06.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to investigate motor responses in healthy subjects and patients with movement disorders, brain and spinal cord injury, neuromuscular diseases, or cardiovascular diseases. This study aims to evaluate the effectiveness of traditional physical activities combined with innovative interventions such as cryotherapy, ultrasound therapy, laser therapy, transcranial magnetic stimulation (TMS), and transcranial direct current stimulation (tDCS). It will also assess the impact of proprioceptive stimuli provided by either the immersive virtual reality (CAREN), or visuo-cognitive-motor enhancement (S.V.T.A.), and music therapy. The main questions it aims to answer are: How do these interventions affect motor activities and their functional recovery? What are the temporal and spatial changes in activation sequences related to motor learning and maintenance? When there is a comparison group: Researchers will compare outcomes between different intervention arms (e.g., physical activity with advanced devices vs. traditional methods) to find out if the advanced interventions result in better motor control and functional recovery. Participants will: * Undergo various rehabilitation protocols including physical activity and advanced interventions. * Be assessed using different tool, such as fMRI, dtMRI, and NIRS to study in vivo neuroimaging and assess changes in brain function and connectivity.
Eligibility Criteria
Inclusion Criteria: * Montreal Cognitive Assessment (MoCA) score (adjusted for age and education) equal to or greater than 20. Exclusion Criteria: * Severe medical and psychiatric disorders potentially affecting the training
Contact & Investigator
Rocco Salvatore Calabrò, PhD
STUDY DIRECTOR
IRCCS Centro Neurolesi Bonino Pulejo
Frequently Asked Questions
Who can join the NCT07066137 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 70 Years, studying Healthy Individuals (Controls). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07066137 currently recruiting?
Yes, NCT07066137 is actively recruiting participants. Contact the research team at mariagrazia.maggio@irccsme.it for enrollment information.
Where is the NCT07066137 trial being conducted?
This trial is being conducted at Messina, Italy.
Who is sponsoring the NCT07066137 clinical trial?
NCT07066137 is sponsored by IRCCS Centro Neurolesi Bonino Pulejo. The principal investigator is Rocco Salvatore Calabrò, PhD at IRCCS Centro Neurolesi Bonino Pulejo. The trial plans to enroll 150 participants.
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