← Browse by Condition

Medical Condition

healthy

Total Trials

75

Recruiting Now

75

Trial Phases

Phase 1, Phase 4, Phase 2

Clinical trials often recruit healthy volunteers for Phase 1 pharmacokinetic and safety studies, vaccine immunogenicity assessments, and normal physiological reference studies. These trials are essential for establishing safe dose ranges and understanding how drugs behave in the absence of disease before testing in patient populations.

Healthy volunteer studies include first-in-human drug trials, vaccine efficacy (flu, RSV, COVID-19, malaria), microbiome intervention studies, exercise physiology research, and device safety assessments. Compensation is often provided; eligibility typically requires no significant medical history and a negative drug screen.

Healthy volunteer trials require participants to be in good general health with no significant medications. Many exclude smokers, pregnant individuals, and those with recent prior trial participation.

Frequently Asked Questions — healthy Clinical Trials

How many clinical trials are currently recruiting for healthy?

ClinicalMetric currently tracks 75 actively recruiting clinical trials for healthy, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 75. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for healthy?

healthy research spans Phase 1 (18 trials), Phase 2 (2 trials), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a healthy clinical trial?

Eligibility criteria for healthy trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 1

18

Phase 2

2

Phase 4

1

Top Sponsors

Eli Lilly and Company 3 trials

Massachusetts General Hospital 2 trials

University of British Columbia 2 trials

Merck Sharp & Dohme LLC 2 trials

Boehringer Ingelheim 2 trials

Recruiting Clinical Trials

Feasibility and Acceptability of Mindful Self-Compassion Among Transgender and Nonbinary Young Adults

University of Rhode Island

NCT05866471 Phase 1

The ENHANCE Study: taVNS and Psilocybin

University of Wisconsin, Madis...

A Study for Imaging the Lower Gastrointestinal Tract Using a Retro-TCE Capsule

Massachusetts General Hospital

NCT07500181 Phase 1

A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of BAL2420 in Healthy Adult Subjects

Basilea Pharmaceutica

Airway Data Collection With the Entarik Feeding Tube System

Theranova, L.L.C.

Development of Prosocial Behaviors and Related Brain Network in Infants of High and Low Risk of ASD

Children's Hospital of Fudan U...

New Orleans Pulmonary Hypertension Biobank

Louisiana State University Hea...

Developing a Pipeline to Employ RNA-Seq as a Complementary Diagnostic Tool in Rare Diseases

Mario Negri Institute for Phar...

NCT07501039 Phase 1

A Phase 1 Study of BLKR201 in Healthy Adult Participants

Formation Bio, Inc.

A Study of TopSpin360 Training Device

Does Listening to Music Alter the Running Mechanics?

Università degli Studi di Sass...

Validating Integrative Multi-omics Approaches in Metabolic Syndrome-related Diseases

Chang Gung Memorial Hospital

NCT06845839 Phase 1

Study to Evaluate CAY001 in Healthy Volunteers

Cayuga Biotech, Inc.

Clinical Explorative Optical Breast Investigations

The Influence of Cortical Lateralization on Selective Motor Control of the Arm Swing During Independent Walking After Stroke.

University Hospital, Ghent

Blood Collection for COM/BSBS

University of Central Florida

Digital Mindset Intervention for Half Marathon Performance

University of Auckland, New Ze...

Effects of Salbutamol in Athletes and Implications for Screening and Sports

University of British Columbia

Beneficial Exposome Study

Stanford University

Personalized Responses to Dietary Composition Trial 3

United States, Unite...

Zoe Global Limited

Intraoperative OCT Guidance of Intraocular Surgery II

Duke University

EARLY-PREG: A Preconception Cohort Study Based on Counterfactuals to Study Maternal-Embryonic Molecular Interactions

MELISA Institute Genomics & Pr...

Feasibility of a Wireless Thermal Capsule Endoscopy to Detect Gastrointestinal Thermal Variance

Massachusetts General Hospital

NCT07090785 Phase 1

A Study of LY4088044 in Healthy Participants

United States, New Z...

Eli Lilly and Company

Reticulospinal Control of Movements

University of Zurich

NCT07850310 Phase 1

A Clinical Trial of MK-8644 in Healthy Participants and Participants With Psoriasis (MK-8644-001)

Merck Sharp & Dohme LLC

Evaluation of the Potential of Grape Consumption to Improve Muscle Strength and Cognitive Function

Western New England University

NCT07678463 Phase 1

A Single and Multiple Ascending Dose Escalation and Food Effect Study of QX-4533 in Healthy Participants

QuantX Biosciences US Inc.

NCT07313722 Phase 1

Study Evaluating Safety of BT01001 Ophthalmic Solution

Beyang Therapeutics Co., Ltd.

NCT06997276 Phase 1

Effect of Hepatic Impairment on the Pharmacokinetics of Mirdametinib

SpringWorks Therapeutics, Inc....

NCT07869940 Phase 1

First-in-human Trial of RBD2080 in Healthy Participants

Suzhou Ribo Life Science Co. L...

Cycle Nation Communities: Increasing Cycling in Glasgow

University of Glasgow

Imaging Measures of Respiratory Health Registry

University of British Columbia

The Gut and Skin Microbiome in Vitiligo Disease Progression

Northwestern University

The Effect of Consumed Berries on Extracellular Vesicle Signalling in the Body

University of Oulu

Evaluation of Methodological and Technical DEvelopmeNts to Improve the Quality and Comfort of Magnetic Resonance Imaging Exam on Voluntary Subjects

Central Hospital, Nancy, Franc...

NCT06745297 Phase 1

A Study in Healthy Men to Test How Well Different Doses of BI 3776528 Are Tolerated

Boehringer Ingelheim

NCT06975241 Phase 4

Observing Metabolism of EPA With Consideration of Genetics And Sex

University of Toronto

Electrophysiological Source Imaging Guided Transcranial Focused Ultrasound

Carnegie Mellon University

Using Artificial Intelligence to Improve Radiologists' Performance in Radiology Report Writing: a Randomised Controlled Trial

Union Hospital, Tongji Medical...

Impact of Phenylalanine Elevations on Brain and Cognition in Adult PKU Carriers

University of Missouri-Columbi...

Investigating Brain Function in People With and Without Visual Snow Syndrome Using Adaptation to Visual Stimuli

University of Minnesota

NCT06623409 Phase 1

Safety and Immunogenicity of V540B in Healthy Adults (V540B-002).

Merck Sharp & Dohme LLC

NCT07908004 Phase 1

A Study to Test How Well Different Doses of BI 3821001 Are Tolerated by Healthy People

Boehringer Ingelheim

Intermittent Fasting on Body Fat and Quality of Life

Loma Linda University

High Resolution Pharyngeal Manometry (HRPM) Biofeedback

NYU Langone Health

Omics Sequencing of Specimen Derived From Mother-Infant-Pairs

Zhujiang Hospital

The MOBY Study: Efficacy of Birth Mobility

Virtual Reality Mirrors Therapy Usability

Turkey (Türkiye)

Abant Izzet Baysal University

NCT07446101 Phase 1

A Study of Mirikizumab Solution (LY3074828) in Healthy Participants

Eli Lilly and Company

Mapping the Impact of Gut Microbiota on Brain and Behavior Through the Lens of GABA

University of Reading

Data Gathering for A10900

NCT07315360 Phase 1

A Study to Learn How the Body Processes the Study Medicine PF-07328948 in People With Reduced Kidney Function

Neural Mechanisms of Cognitive Assessment and Rehabilitation for Cognitive Decline

National Research Center for R...

Breathing & Blood Pressure

Florida State University

Muscle Mass, Quality, and the Menopause: Sex-specific Strategies to Mitigate Sarcopenia in Ageing Populations

University of Nottingham

NCT07169630 Phase 1

PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)

National Institute of Mental H...

Interaction Between Dairy and Gut Hormone Response on Cognitive Performance in Children.

Toronto Metropolitan Universit...

Telemedicine to Support Living Kidney Donor Candidates

University of California, Irvi...

NCT07403552 Phase 1

Evaluate the Pharmacokinetics, Safety, and Tolerability of NSHO-101 in Healthy Participants

Ensho Therapeutics, Inc.

NCT07165002 Phase 1

A Study of the Pharmacokinetics and Safety of LY3537031 in Participants With Normal Liver Function and With Mild, Moderate, or Severe Liver Impairment

Hungary, New Zealand...

Eli Lilly and Company

Pregnancy 24/7 Offspring Study

Difference in Acute Responses of Vascular Function to Moderate-intensity and High-intensity Interval Training in Healthy and Prehypertensive Individuals

University of Ljubljana

Olfactory Transcranial Focused Ultrasound

Medical University of South Ca...

Effect of Smoking and Time of Day on Eosinophils

Marek Lommatzsch

NCT07715864 Phase 2

Naturally Produced Cannabinoids for Neuroprotection From Concussion

University of Regina

LPFC Organization in Emotion-Duration Difference Estimation

University of California, Sant...

Identification of Biomarkers for Stress Vulnerability and Resilience

University of Michigan

Evaluating a Digital Single-session Intervention for Adolescent Mental Health in New Zealand

The University of Waikato

Oxytocin's Effects on Real Time-fMRI Neurofeedback Training of Anterior Insula Activity

University of Electronic Scien...

Continuous vs. Intermittent Rt-fMRI Neurofeedback Training of the Anterior Insula

University of Electronic Scien...

Influence of Brain Oscillation-Dependent TMS on Motor Function

National Institute of Neurolog...

The Mitopure Challenge to Detect Levels of Urolithin A in Dried Blood Spots

NCT07191353 Phase 2

Resistance Training and Rapamycin to Enhance Bone Formation in Postmenopausal Women

Odense University Hospital

Effect of a 16-day Hot and Cold Acclimation on Adaptive Responses and Health-related Indicators

Lithuanian Sports University

Related Conditions

stroke (3) crohn disease (2) inflammatory bowel diseases (2) retinal disease (2) aging (2) psychedelic experiences (1) vagus nerve stimulation (1) lynch syndrome (1) autism or autistic traits (1) pulmonary hypertension (1) systemic sclerosis (1) mixed connective tissue disease (1)

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology