Medical Condition

healthy

Total Trials

67

Recruiting Now

67

Trial Phases

Phase 1, Phase 2, Phase 4

Clinical trials often recruit healthy volunteers for Phase 1 pharmacokinetic and safety studies, vaccine immunogenicity assessments, and normal physiological reference studies. These trials are essential for establishing safe dose ranges and understanding how drugs behave in the absence of disease before testing in patient populations.

Healthy volunteer studies include first-in-human drug trials, vaccine efficacy (flu, RSV, COVID-19, malaria), microbiome intervention studies, exercise physiology research, and device safety assessments. Compensation is often provided; eligibility typically requires no significant medical history and a negative drug screen.

Healthy volunteer trials require participants to be in good general health with no significant medications. Many exclude smokers, pregnant individuals, and those with recent prior trial participation.

Frequently Asked Questions — healthy Clinical Trials

How many clinical trials are currently recruiting for healthy?

ClinicalMetric currently tracks 67 actively recruiting clinical trials for healthy, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 67. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for healthy?

healthy research spans Phase 1 (23 trials), Phase 2 (2 trials), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a healthy clinical trial?

Eligibility criteria for healthy trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 1

Phase 2

Phase 4

Top Sponsors

Boehringer Ingelheim 3 trials

Eli Lilly and Company 3 trials

Mayo Clinic 2 trials

University of Michigan 2 trials

University of Copenhagen 2 trials

healthy

Frequently Asked Questions — healthy Clinical Trials

Recruiting Clinical Trials

Evaluation of Methodological and Technical DEvelopmeNts to Improve the Quality and Comfort of Magnetic Resonance Imaging Exam on Voluntary Subjects

"Multifactorial Risk Stratification in Acute and Chronic Cardiovascular Disease"

Pulsed Electromagnetic Fields in Preventing Physical Deconditioning in Patients Undergoing Prolonged Hospitalization

The Effect of Simulation-Based Training on Physiotherapy Student's Self-Confidence and Satisfaction Level

Effect of Flexibility on Postural Stability

A Study in Healthy Men to Test How Well Different Doses of BI 3776528 Are Tolerated

Viral Mucosal Reprogramming

Individual Differences in Cognitive Control Predict Real-time fMRI Neurofeedback Performance

Phase I Study of CPD704 Inhalation Suspension in Healthy Subjects

Quantifying 18kDa TSPO Expression in the Lung in Pulmonary Artery Hypertension (PAH)

Prodromal Parkinsonian Features in GBA1 Mutation Carriers

Study of CM383 in Healthy Subjects

Fisetin Supplementation for Healthy Aging

The Effect of Exposure to Aversive Non-verbal Vocalizations on Pain Tolerance

Ex Vivo Expansion (ACT-X)

Observing Metabolism of EPA With Consideration of Genetics And Sex

Parents as Partners: Effectiveness of the Program in a Portuguese Sample

A Study of LY3981314 in Healthy Participants

Safety, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of Ascending Doses BCD-261 in Healthy Subjects

Development of a Non-invasive Screening Tool to Predict Metabolic Dysfunction-associated Steatotic Liver Disease

A Study of LY3971297 in Healthy Participants

Muscle Mass, Quality, and the Menopause: Sex-specific Strategies to Mitigate Sarcopenia in Ageing Populations

Single and Multiple Dose Pharmacokinetics (PK) of Aramchol From an Aramchol Meglumine Tablet

Identification of Biomarkers for Stress Vulnerability and Resilience

Neuromodulation of Brain and Emotional Responses to Psychological Stress

Study to Evaluate Pharmacokinetics, Relative Bioavailability, Palatability of Obefazimod Minitablet Formulation

Urinary Concentration After Salmeterol

A Comparison of Neuromuscular Recruitment in Trained and Untrained Adults

Adversity, Brain and Opioid Use Study

Development of Novel MR Techniques Using Volunteer Participants

A Drug-Drug Interaction Study of Itraconazole and Opevesostat (MK-5684) in Healthy Adult Male Participants (MK-5684-017)

The ENHANCE Study: taVNS and Psilocybin

Gait and Balance Impairment in Rare and Very Rare Neurological Diseases

Normal Donor Blood Draws for Platelet Studies and Biomarker Evaluation (ND-PLT)

Evaluation of the Safety, Tolerability and Pharmacokinetics of HY8931 in Healthy Adult Participants

Physiology of Human Brain Connectivity

Comparison of Preoxygenation Techniques in Healthy Volunteers With Monitoring of End-tidal Oxygen Fraction (FeO₂) and Oxygen Reserve Index (ORI)

Effects of Variations in Caffeinated Beverages on Well-being

A Single- and Multiple-Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of LY4066708 in Healthy Participants

The Influence of Cortical Lateralization on Selective Motor Control of the Arm Swing During Independent Walking After Stroke.

Study of Student Flourishing

Influence of Fitzpatrick Skin Phototype and Body Mass Index on Non-invasive Optoacoustic Imaging

Salmeterol Effect on Exercise Performance

A Study in Healthy People to Test How Vicadrostat Affects the Heart

Non-invasive Preoperative Tissue Evaluation in Head and Neck Tumor Patients Using Multispectral Optoacoustic Tomography (MSOT)

MAD Study of IA-14069

Study of New Magnetic Resonance Imaging Methods of the Brain

Drug Discovery for Parkinson's With Mutations in the GBA Gene

Health4Life a Digital Intervention to Promote Healthy Lifestyle Behaviours From the Start of Life

Effects of Muscle Cooling on Motor Unit Firing of the Quadriceps

Effect of Oligosaccharides and Optimizing Multiple Nutrients to Infant Formula on Growth and Development of Infants

Comparison of Cuff-Less Wrist Wearable Blood Pressure Device to Cuff Based Blood Pressure Measuring Devices

Development of Prosocial Behaviors and Related Brain Network in Infants of High and Low Risk of ASD

The Effect of Coffee on People with High Intensity Exercise and the Characteristics of Caffeine Metabolism

Direct Comparison of Altered States of Consciousness Induced by LSD, Psilocybin, and DMT in Healthy Participants

Identification of Neuroinflammation and Neuroimaging Biomarkers Through Data Driven Artificial Intelligence Techniques for Unraveling the Heterogeneity of Aged Subjects at Risk of Dementia and to Better Inform Prevention Strategies

Clinical Study to Estimate Bone Mineral Density With the POROUS Ultrasound Device

A First-in-human Study of the Safety of an Immunosuppressive Antibody (IMP761) in Healthy Volunteers

A Study of BGM0504 Tablets in Healthy and Non-diabetic Overweight or Obese Chinese Subjects

A Study of SYNT-101 to Test Safety, Tolerability and Pharmacodynamics of SYNT-101 in Healthy and Overweight Adults

SV2A Density Cannabis Use Disorder

To Evaluate the Safety/Tolerability and Pharmacokinetic Characteristics in Healthy Volunteers

Dinner Time for Obesity and Prediabetes

Effects of Salbutamol in Athletes and Implications for Screening and Sports

A Study to Test How Well Different Doses of BI 3804379 Are Tolerated by Healthy People

A Study to Evaluate the Safety of Increasing Doses of DF5112 in Healthy Adults

SV2A & TSPO PET Imaging Measures to Reveal Mechanisms of HIV Neuropathogenesis During Antiretroviral Therapy