State MO
Clinical Trials in Missouri
Missouri is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Missouri and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 275 actively recruiting studies with Missouri sites out of 275 registered in total. The busiest research areas in Missouri are Obesity, Heart Failure, Multiple Myeloma. Leading sponsors running trials in the state include Washington University School of Medicine, National Cancer Institute (NCI), AstraZeneca. By stage, Missouri trials break down as Phase 1 (52), Phase 2 (71), Phase 3 (78), Phase 4 (10).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Missouri
Frequently Asked Questions — Clinical Trials in Missouri
How many clinical trials are currently recruiting in Missouri?
ClinicalMetric currently tracks 275 actively recruiting clinical trials with at least one location in Missouri. The total number of registered studies—including active but not currently enrolling trials—is 275. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Missouri?
Missouri hosts clinical trials across a broad range of medical conditions, including Obesity, Heart Failure, Multiple Myeloma, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Missouri serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Missouri?
To join a clinical trial in Missouri, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Missouri maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Missouri
NCT05911568 N/A
Recruiting
Treatment With Endovascular Intervention for STroke Patients With Existing Disab...
Condition
Stroke
Enrollment
1,060 pts
Location
United States
Sponsor
University of Cincinnati
NCT07455747 N/A
Recruiting
Real-World Treatment of Extracranial Carotid Artery Disease With the ENROUTE™ Tr...
Condition
Extracranial Carotid Artery Disease
Enrollment
5,000 pts
Location
United States
Sponsor
Boston Scientific Corporation
NCT07796178 Phase 4
Recruiting
Evaluation of Lacrifill
Condition
Dry Eye
Enrollment
40 pts
Location
United States
Sponsor
Eye Research Associates, LLC
NCT07914673 Phase 4
Recruiting
Age-Associated Differences in Germinal Center Responses to Influenza and Rabies ...
Condition
Healthy Adult Participants
Enrollment
40 pts
Location
United States
Sponsor
Washington University School o
NCT07507422 N/A
Recruiting
Post Market Evaluation of Real World Outcomes and Durability to Support Implanta...
Condition
Chronic Pain
Enrollment
970 pts
Location
United States, Belgium, France
Sponsor
Medtronic
NCT07385105 N/A
Recruiting
Evaluation of Cognitive Behavioral Therapy for Insomnia (CBT-I) in Individuals W...
Condition
Sleep Architecture
Enrollment
15 pts
Location
United States
Sponsor
University of Missouri-Columbi
NCT07630974 Phase 1, Phase 2
Recruiting
A Study of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refr...
Condition
Malignant Neoplasm
Enrollment
134 pts
Location
United States, Australia, Belgium
Sponsor
Merck Sharp & Dohme LLC
NCT06475989 Phase 3
Recruiting
Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer
Condition
Refractory Differentiated Thyroid Gland Carcinoma
Enrollment
264 pts
Location
United States
Sponsor
ECOG-ACRIN Cancer Research Gro
NCT05123482 Phase 1, Phase 2
Recruiting
A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Adv...
Condition
Breast Cancer
Enrollment
460 pts
Location
United States, Australia, Belgium
Sponsor
AstraZeneca
NCT07681596 Phase 1, Phase 2
Recruiting
A Modular, Phase I/II, Multicentre Study to Evaluate AZD4045, in Participants Wi...
Condition
Relapsed or Refractory Multiple Myeloma
Enrollment
101 pts
Location
United States, Australia
Sponsor
AstraZeneca
NCT06930755 Phase 1
Recruiting
Study of NMS-03305293 in Adult Patients With Relapsed Ovarian Cancer
Condition
Ovarian Cancer
Enrollment
24 pts
Location
United States
Sponsor
Nerviano Medical Sciences
NCT06976268 Phase 2, Phase 3
Recruiting
A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment...
Condition
Parkinson Disease
Enrollment
550 pts
Location
United States
Sponsor
Biohaven Therapeutics Ltd.
NCT07114874 Phase 3
Recruiting
NBI-1117568-SCZ3032: Long-Term Evaluation of NBI-1117568 in Adults With Schizoph...
Condition
Schizophrenia
Enrollment
600 pts
Location
United States, Bulgaria, Puerto Rico
Sponsor
Neurocrine Biosciences
NCT07825597 Phase 2
Recruiting
Indocyanine Green With Near Infrared Imaging for Intraoperative Visualization of...
Condition
Head and Neck Squamous Cell Carcinoma
Enrollment
25 pts
Location
United States
Sponsor
Washington University School o
NCT06608823 N/A
Recruiting
ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™
Condition
Aortic Regurgitation
Enrollment
1,016 pts
Location
United States
Sponsor
JenaValve Technology, Inc.
NCT07227246 Phase 3
Recruiting
Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2
Condition
Intracerebral Hemorrhage
Enrollment
350 pts
Location
United States, Canada, Germany
Sponsor
Joseph Broderick, MD
NCT05626114 Phase 2
Recruiting
A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Acti...
Condition
Geographic Atrophy
Enrollment
60 pts
Location
United States, Israel
Sponsor
Genentech, Inc.
NCT04363684 N/A
Recruiting
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)
Condition
Frontotemporal Lobar Degeneration (FTLD)
Enrollment
2,100 pts
Location
United States, Canada
Sponsor
Mayo Clinic
NCT06562543 Phase 4
Recruiting
A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populati...
Condition
Colorectal Cancer
Enrollment
78 pts
Location
United States, Puerto Rico
Sponsor
Takeda
NCT04380740 Phase 2
Recruiting
Extended vs Short-term Abatacept Dosing for Graft Versus Host Disease Prophylaxi...
Condition
Graft Vs Host Disease
Enrollment
160 pts
Location
United States
Sponsor
Boston Children's Hospital
NCT05382559 Phase 1
Recruiting
A Study of ASP3082 in Adults With Advanced Solid Tumors
Condition
Solid Tumor
Enrollment
681 pts
Location
United States, China, France
Sponsor
Astellas Pharma Inc
NCT07270406 N/A
Recruiting
Healthy Behaviors for Insomnia Prevention in People With HIV and Ongoing Pain
Condition
Chronic Pain
Enrollment
200 pts
Location
United States
Sponsor
Washington University School o
NCT07278778 N/A
Recruiting
Cancer Care Companion
Condition
Pediatric Cancer
Enrollment
40 pts
Location
United States
Sponsor
Washington University School o
NCT05570448 N/A
Recruiting
Anti-Reflux Endoscopic TX Using APC (AREA) in GERD Patients: (The AREA Study)
Condition
Gastro Esophageal Reflux
Enrollment
36 pts
Location
United States
Sponsor
Midwest Veterans' Biomedical R
NCT07623135 Phase 3
Recruiting
Lumateperone for Late-Life Depression
Condition
Treatment Resistant Depression (TRD)
Enrollment
100 pts
Location
United States
Sponsor
Eric Lenze
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology