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nsclc

Total Trials
19
Recruiting Now
19
Trial Phases
Phase 3, Phase 1, Phase 2

ClinicalMetric tracks all active clinical trials for nsclc sourced from ClinicalTrials.gov. Each listing includes the NCT identifier, current recruitment status, phase, primary endpoints, sponsor, estimated enrollment, and participating countries — updated daily as new studies open and status changes.

  • Recruiting trials currently enrolling participants, with eligibility criteria and age requirements
  • Phase 1–4 studies from early safety trials to post-marketing surveillance
  • NIH, pharmaceutical sponsor, and academic medical center studies worldwide
  • AI-powered plain-language summary available for every trial listing

Frequently Asked Questions — nsclc Clinical Trials

How many clinical trials are currently recruiting for nsclc?
ClinicalMetric currently tracks 19 actively recruiting clinical trials for nsclc, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 19. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for nsclc?
nsclc research spans Phase 1 (9 trials), Phase 2 (10 trials), Phase 3 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a nsclc clinical trial?
Eligibility criteria for nsclc trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
9
Phase 2
10
Phase 3
1
Top Sponsors
A2 Biotherapeutics Inc. 2 trials
Revolution Medicines, Inc. 2 trials
Shanghai Chest Hospital 1 trial
Merck Sharp & Dohme LLC 1 trial
Xuanzhu Biopharmaceutical Co., Ltd. 1 trial

Recruiting Clinical Trials

NCT05701787
Recruiting

Molecular Landscape Analysis and Clinical Implications for NSCLC Patients With Rare Mutations

Enrollment
500 pts
Location
China
Sponsor
Shanghai Chest Hospital
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NCT06422143 Phase 3
Recruiting

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

Enrollment
851 pts
Location
United States, Argen...
Sponsor
Merck Sharp & Dohme LLC
View Trial →
NCT05772455 Phase 1
Recruiting

A Study of XZB-0004 in Patients With Solid Tumors

Enrollment
128 pts
Location
China
Sponsor
Xuanzhu Biopharmaceutical Co.,...
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NCT06248606 Phase 2
Recruiting

Adagrasib + SRS for Patients With Metastatic KRAS G12C-mutated NSCLC With Untreated Brain Metastases

Enrollment
30 pts
Location
United States
Sponsor
Ryan Gentzler, MD
View Trial →
NCT06864624 Phase 2
Recruiting

Perioperative Treatment of Sunvozertinib in Stage II-IIIB NSCLC

Enrollment
27 pts
Location
China
Sponsor
Tang-Du Hospital
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NCT04720339
Recruiting

Molecular Monitoring of cfDNA by ddPCR in Non-small Cell Lung Cancer Treated by Immunotherapy.

Enrollment
250 pts
Location
France
Sponsor
University Hospital, Strasbour...
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NCT06945705 Phase 2
Recruiting

A Clinical Trial of Furmonertinib Combined With Anlotinib as First-line Treatment for Advanced NSCLC With EGFR-sensitive Mutations and Brain Metastasis

Enrollment
146 pts
Location
China
Sponsor
Henan Cancer Hospital
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NCT06362369 Phase 1, Phase 2
Recruiting

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

Enrollment
126 pts
Location
United States
Sponsor
7 Hills Pharma, LLC
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NCT06816992 Phase 1
Recruiting

ORIC-114 in Combination With Subcutaneous Amivantamab in Patients With EGFR Exon20 Insertion Mutant NSCLC

Enrollment
76 pts
Location
United States, Austr...
Sponsor
ORIC Pharmaceuticals
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NCT05877430 Phase 1, Phase 2
Recruiting

Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer

Enrollment
160 pts
Location
United States, South...
Sponsor
CJ Bioscience, Inc.
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NCT04981119
Recruiting

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

Enrollment
200 pts
Location
United States
Sponsor
A2 Biotherapeutics Inc.
View Trial →
NCT06731413 Phase 2
Recruiting

Reduced CT + Anti-PD-1 as First Line Tx in Vulnerable Older Adults w/Adv <50% PD-L1 Non-Small Cell Lung Cancer (NSCLC)

Enrollment
40 pts
Location
United States
Sponsor
Virginia Commonwealth Universi...
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NCT06097962 EARLY_Phase 1
Recruiting

Safety and Efficacy of NK510 to Treat NSCLC

Enrollment
12 pts
Location
China
Sponsor
Base Therapeutics (Shanghai) C...
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NCT07082179 Phase 2
Recruiting

A Prospective Phase II Clinical Study of Immunotherapy Combined With Chemotherapy for Stage III Unresectable Non-small Cell Lung Cancer

Enrollment
33 pts
Location
China
Sponsor
Jiangsu Cancer Institute & Hos...
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NCT07397338 Phase 1, Phase 2
Recruiting

Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors

Enrollment
370 pts
Location
United States
Sponsor
Revolution Medicines, Inc.
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NCT07349537 Phase 1
Recruiting

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

Enrollment
574 pts
Location
United States
Sponsor
Revolution Medicines, Inc.
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NCT06051695 Phase 1, Phase 2
Recruiting

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

Enrollment
474 pts
Location
United States
Sponsor
A2 Biotherapeutics Inc.
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NCT06657222 Phase 1, Phase 2
Recruiting

First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

Enrollment
250 pts
Location
United States, Canad...
Sponsor
Tubulis GmbH
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NCT07247227
Recruiting

Real-world First-line Sugemalimab-Chemotherapy in Advanced NSCLC

Enrollment
150 pts
Location
China
Sponsor
Peking Union Medical College
View Trial →
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology