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Clinical Trials in Maryland

Maryland is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Maryland and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.

Right now ClinicalMetric tracks 406 actively recruiting studies with Maryland sites out of 406 registered in total. The busiest research areas in Maryland are Breast Cancer, Obesity, Hypertension. Leading sponsors running trials in the state include Johns Hopkins University, National Cancer Institute (NCI), National Institute of Allergy and Infectious Diseases (NIAID). By stage, Maryland trials break down as Phase 1 (65), Phase 2 (96), Phase 3 (88), Phase 4 (11).

All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.

Total Trials
406
Recruiting Now
406
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Top Conditions in Maryland
Breast Cancer (7)Obesity (7)Hypertension (6)HIV (5)Bladder Cancer (5)Endometrial Cancer (5)Sickle Cell Disease (4)Neurofibromatosis 1 (4)Healthy (4)Carcinoma, Non-Small-Cell Lung (4)Healthy Volunteers (4)Myelodysplastic Syndromes (4)

Frequently Asked Questions — Clinical Trials in Maryland

How many clinical trials are currently recruiting in Maryland?
ClinicalMetric currently tracks 406 actively recruiting clinical trials with at least one location in Maryland. The total number of registered studies—including active but not currently enrolling trials—is 406. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Maryland?
Maryland hosts clinical trials across a broad range of medical conditions, including Breast Cancer, Obesity, Hypertension, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Maryland serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Maryland?
To join a clinical trial in Maryland, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Maryland maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.

Recruiting Trials in Maryland

NCT07300969 Phase 2
Recruiting
A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression
Condition
Major Depressive Disorder (MDD)
Enrollment
300 pts
Location
United States, Bulgaria, Czechia
Sponsor
Draig Therapeutics Ltd
View Trial →
NCT06325722 N/A
Recruiting
Diet Order Effects of Low Fat vs. Low Carb Diets on Body Fat Change
Condition
Overweight
Enrollment
42 pts
Location
United States
Sponsor
National Institute of Diabetes
View Trial →
NCT07592273 Phase 2, Phase 3
Recruiting
Surabgene Lomparvovec Administered in the Suprachoroidal Space in Adult Particip...
Condition
Diabetic Retinopathy
Enrollment
576 pts
Location
United States, Puerto Rico
Sponsor
AbbVie
View Trial →
NCT07215702 Phase 2
Recruiting
A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Parti...
Condition
Sepsis
Enrollment
124 pts
Location
United States, Argentina, Belgium
Sponsor
AstraZeneca
View Trial →
NCT07625345 Phase 1
Recruiting
Evaluation of [11C]ZTP-1 to Image PDE4B
Condition
Healthy
Enrollment
40 pts
Location
United States
Sponsor
National Institute of Mental H
View Trial →
NCT06088381 Phase 2
Recruiting
Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Ci...
Condition
Head and Neck Cancer
Enrollment
61 pts
Location
United States
Sponsor
University of Maryland, Baltim
View Trial →
NCT06127407 Phase 3
Recruiting
Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chon...
Condition
Locally Advanced or Metastatic Conventional Chondrosarcoma With an IDH1 Mutation, Untreated or Previously Treated With 1 Systemic Treatment Regimen
Enrollment
136 pts
Location
United States, Australia, Belgium
Sponsor
Servier Bio-Innovation LLC
View Trial →
NCT06623357 N/A
Recruiting
Pilot Test of Caregiver Training Protocol for Brachial Plexus Birth Injury
Condition
Brachial Plexus Birth Palsy
Enrollment
20 pts
Location
United States
Sponsor
Hugo W. Moser Research Institu
View Trial →
NCT03723928 N/A
Recruiting
S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Re...
Condition
Anatomic Stage IV Breast Cancer AJCC v8
Enrollment
739 pts
Location
United States, Guam, Puerto Rico
Sponsor
SWOG Cancer Research Network
View Trial →
NCT06500975 N/A
Recruiting
Long Term Outcomes After Vestibular Implantation
Condition
Bilateral Vestibular Hypofunction
Enrollment
32 pts
Location
United States
Sponsor
Johns Hopkins University
View Trial →
NCT00018057 Phase 2
Recruiting
Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders
Condition
Anxiety Disorders
Enrollment
3,500 pts
Location
United States
Sponsor
National Institute of Mental H
View Trial →
NCT07160244 Phase 3
Recruiting
BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregn...
Condition
Healthy
Enrollment
6,000 pts
Location
United States, Argentina, Brazil
Sponsor
Pfizer
View Trial →
NCT04166409 Phase 3
Recruiting
A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients Wit...
Condition
Low Grade Astrocytoma
Enrollment
170 pts
Location
United States, Canada, Puerto Rico
Sponsor
National Cancer Institute (NCI
View Trial →
NCT03624374 N/A
Recruiting
Natural History Study of Leukoencephalopathy With Brainstem and Spinal Cord Invo...
Condition
Leukoencephalopathies
Enrollment
100 pts
Location
United States
Sponsor
Hugo W. Moser Research Institu
View Trial →
NCT06980428 Phase 1
Recruiting
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynam...
Condition
Healthy Participants
Enrollment
136 pts
Location
United States
Sponsor
AstraZeneca
View Trial →
NCT07165028 Phase 3
Recruiting
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associ...
Condition
Metabolic Dysfunction-Associated Steatotic Liver Disease
Enrollment
4,500 pts
Location
United States, Argentina, Australia
Sponsor
Eli Lilly and Company
View Trial →
NCT00789009 N/A
Recruiting
Clinical and Immunologic Monitoring of Patients With Known or Suspected HIV Infe...
Condition
HIV
Enrollment
600 pts
Location
United States
Sponsor
National Institute of Allergy
View Trial →
NCT05762107 Phase 2
Recruiting
A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes
Condition
Type 1 Diabetes Mellitus With Hypoglycemia
Enrollment
186 pts
Location
United States, Canada
Sponsor
Zucara Therapeutics Inc.
View Trial →
NCT05511909 Phase 2
Recruiting
Evaluating Buspirone to Treat Opioid Withdrawal
Condition
Opioid Use Disorder
Enrollment
100 pts
Location
United States
Sponsor
University of Maryland, Baltim
View Trial →
NCT04176198 Phase 1, Phase 2
Recruiting
A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis
Condition
Myelofibrosis
Enrollment
240 pts
Location
United States, Australia, Belgium
Sponsor
Sumitomo Pharma America, Inc.
View Trial →
NCT04959175 Phase 1, Phase 2
Recruiting
Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Olde...
Condition
Hematologic Neoplasms
Enrollment
320 pts
Location
United States
Sponsor
National Cancer Institute (NCI
View Trial →
NCT05289934 N/A
Recruiting
Effects of Recorded Music on Clinical and EEG Seizure Activity
Condition
Epilepsy
Enrollment
10 pts
Location
United States
Sponsor
Johns Hopkins University
View Trial →
NCT06325709 Phase 1, Phase 2
Recruiting
Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-...
Condition
Chronic Granulomatous Disease (CGD)
Enrollment
15 pts
Location
United States
Sponsor
National Institute of Allergy
View Trial →
NCT05265299 Phase 3
Recruiting
Trial to Determine Effective Aspirin Dose in COPD
Condition
Pulmonary Disease, Chronic Obstructive
Enrollment
48 pts
Location
United States
Sponsor
Johns Hopkins University
View Trial →
NCT05885698 N/A
Recruiting
MYLUNG Consortium Part 3: Observational Study
Condition
Carcinoma, Non-Small-Cell Lung
Enrollment
7,500 pts
Location
United States
Sponsor
US Oncology Research
View Trial →
Page 2 of 17 — 406 trials total
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology