State PA
Clinical Trials in Pennsylvania
Pennsylvania is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Pennsylvania and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 478 actively recruiting studies with Pennsylvania sites out of 478 registered in total. The busiest research areas in Pennsylvania are Prostate Cancer, Ovarian Cancer, Breast Cancer. Leading sponsors running trials in the state include University of Pennsylvania, University of Pittsburgh, Abramson Cancer Center at Penn Medicine. By stage, Pennsylvania trials break down as Phase 1 (82), Phase 2 (138), Phase 3 (101), Phase 4 (17).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Pennsylvania
Frequently Asked Questions — Clinical Trials in Pennsylvania
How many clinical trials are currently recruiting in Pennsylvania?
ClinicalMetric currently tracks 478 actively recruiting clinical trials with at least one location in Pennsylvania. The total number of registered studies—including active but not currently enrolling trials—is 478. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Pennsylvania?
Pennsylvania hosts clinical trials across a broad range of medical conditions, including Prostate Cancer, Ovarian Cancer, Breast Cancer, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Pennsylvania serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Pennsylvania?
To join a clinical trial in Pennsylvania, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Pennsylvania maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Pennsylvania
NCT07083583 N/A
Recruiting
Impact of IV Iron on Bleeding Symptoms in Iron Deficient Patients With Inherited...
Condition
Bleeding Disorders
Enrollment
40 pts
Location
United States
Sponsor
Nicoletta C Machin
NCT07541079 Phase 3
Recruiting
A Study Evaluating Adherence, Tolerability, and Patient Reported Outcomes of Gir...
Condition
Early Breast Cancer
Enrollment
300 pts
Location
United States
Sponsor
Genentech, Inc.
NCT05658913 N/A
Recruiting
Tau PET/CT Imaging in the Mismatch Prospective Cohort Study (MPC-TAU)
Condition
Alzheimer's Disease
Enrollment
100 pts
Location
United States
Sponsor
University of Pennsylvania
NCT06767514 Phase 3
Recruiting
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patie...
Condition
Non-Small Cell Lung Cancer
Enrollment
780 pts
Location
United States, Belgium, Canada
Sponsor
Summit Therapeutics
NCT04725916 N/A
Recruiting
Studying How Outpatient Water affEcts Risks With Drains (SHOWER Study)
Condition
Postoperative Wound Infection
Enrollment
100 pts
Location
United States
Sponsor
Sean Devitt
NCT06652347 N/A
Recruiting
Understanding the Preferences and Views of Older Adults on the Use of Geriatric ...
Condition
Care Delivery
Enrollment
100 pts
Location
United States
Sponsor
Fox Chase Cancer Center
NCT07397338 Phase 1, Phase 2
Recruiting
Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Sol...
Condition
Advanced Solid Tumors
Enrollment
370 pts
Location
United States
Sponsor
Revolution Medicines, Inc.
NCT07116967 Phase 3
Recruiting
Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants Wit...
Condition
Plaque Psoriasis
Enrollment
3,040 pts
Location
United States, Argentina, Australia
Sponsor
Bristol-Myers Squibb
NCT06138067 N/A
Recruiting
Patient Navigation Program to Improve Clinical Trial Enrollment in Cancer Patien...
Condition
Prostate Cancer
Enrollment
90 pts
Location
United States
Sponsor
Sidney Kimmel Comprehensive Ca
NCT06290401 N/A
Recruiting
A Socio-ecological Approach for Improving Self-management in Adolescents With SC...
Condition
Anemia, Sickle Cell
Enrollment
310 pts
Location
United States
Sponsor
Children's Hospital Medical Ce
NCT07770828 Phase 3
Recruiting
Phase 3 Study to Assess Efficacy, Safety & Tolerability of OCU410 For Geographic...
Condition
Dry Age-related Macular Degeneration
Enrollment
237 pts
Location
United States
Sponsor
Ocugen
NCT05677971 Phase 3
Recruiting
Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People ...
Condition
Alpha1-Antitrypsin Deficiency
Enrollment
160 pts
Location
United States, Australia, Austria
Sponsor
Takeda
NCT02735707 Phase 3
Recruiting
Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acqu...
Condition
Respiratory Tract Diseases
Enrollment
20,000 pts
Location
United States, Australia, Belgium
Sponsor
UMC Utrecht
NCT07222436 N/A
Recruiting
Circulating Tumor DNA in High Risk Localized Prostate Cancer
Condition
Prostate Cancer
Enrollment
24 pts
Location
United States
Sponsor
University of Pittsburgh
NCT04771130 Phase 1, Phase 2
Recruiting
A Study of BGB-11417 in Participants With Myeloid Malignancies
Condition
Acute Myeloid Leukemia
Enrollment
260 pts
Location
United States, Australia, China
Sponsor
BeOne Medicines
NCT07571109 Phase 3
Recruiting
AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps...
Condition
Obesity
Enrollment
300 pts
Location
United States, Australia, China
Sponsor
Novo Nordisk A/S
NCT05887609 Phase 2
Recruiting
An Evaluation of Maintenance Therapy Combination Mirvetuximab Soravtansine and O...
Condition
Ovary Cancer
Enrollment
53 pts
Location
United States
Sponsor
University of Colorado, Denver
NCT06247787 Phase 1
Recruiting
A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine a...
Condition
Recurrent Childhood Acute Myeloid Leukemia
Enrollment
36 pts
Location
United States
Sponsor
Children's Oncology Group
NCT06736574 Phase 3
Recruiting
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With S...
Condition
Heart Failure
Enrollment
1,800 pts
Location
United States, Canada, China
Sponsor
Cytokinetics
NCT06626035 Phase 3
Recruiting
Evaluation of Analgesia for Cardiac Elective Surgery in Children
Condition
Pediatric Cardiac Surgery
Enrollment
500 pts
Location
United States
Sponsor
Senthil Sadhasivam
NCT07191782 N/A
Recruiting
Examining the Efficacy of the PRAISE With Coaching Program
Condition
Aggression Childhood
Enrollment
1,008 pts
Location
United States
Sponsor
Children's Hospital of Philade
NCT05608317 N/A
Recruiting
A Clinical Investigation to Follow the Progress of Exuding Chronic Venous Leg Ul...
Condition
Wounds
Enrollment
20 pts
Location
United States
Sponsor
Molnlycke Health Care AB
NCT07286318 EARLY_Phase 1
Recruiting
A Randomized Controlled Trial of Topical 5% Niacinamide for Skin Cancer Preventi...
Condition
Skin Cancer
Enrollment
20 pts
Location
United States
Sponsor
Marissa Lobl
NCT03266640 Phase 2
Recruiting
Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CM...
Condition
Cytomegalovirus Infections
Enrollment
20 pts
Location
United States
Sponsor
New York Medical College
NCT05558059 N/A
Recruiting
Imaging Retinal Vasculature in Infant Eyes
Condition
Retinopathy of Prematurity
Enrollment
16 pts
Location
United States
Sponsor
Duke University
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology