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Recruiting Phase 4 NCT05803941

NCT05803941 Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer

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Clinical Trial Summary
NCT ID NCT05803941
Status Recruiting
Phase Phase 4
Sponsor Novartis Pharmaceuticals
Condition Prostate Cancer
Study Type INTERVENTIONAL
Enrollment 700 participants
Start Date 2023-08-14
Primary Completion 2033-07-20

Eligibility & Interventions

Sex Male only
Min Age 18 Years
Max Age 100 Years
Study Type INTERVENTIONAL
Interventions
AAA617

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

Phase 4 studies follow an already-approved treatment in real-world conditions to monitor long-term safety and effectiveness.

This trial targets 700 participants in total. It began in 2023-08-14 with a primary completion date of 2033-07-20.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this post-marketing study is to further characterize the long-term outcome of known or potential risks of lutetium (177Lu) vipivotide tetraxetan also known as \[177Lu\]Lu-PSMA-617 or 177Lu-PSMA-617 and hereinafter referred to as AAA617. The study also seeks to further characterize (as possible) any other AAA617 causally related serious adverse event(s) in the long-term in adults with prostate cancer who received at least one dose of AAA617 from interventional, Phase I-IV Novartis sponsored clinical trials.

Eligibility Criteria

Inclusion Criteria: * Signed informed consent must be obtained prior to participation in the study * Must have received at least one dose of AAA617 within an interventional, Phase I-IV Novartis sponsored clinical trial in prostate cancer and have fulfilled the trial's requirements that allows them to participate in this study. Exclusion Criteria: \- Inability to complete the needed investigational examinations due to any reason.

Contact & Investigator

Central Contact

Novartis Pharmaceuticals

✉ novartis.email@novartis.com

📞 1-888-669-6682

Principal Investigator

Novartis Pharmaceuticals

STUDY DIRECTOR

Novartis Pharmaceuticals

Frequently Asked Questions

Who can join the NCT05803941 clinical trial?

This trial is open to male participants only, aged 18 Years or older, up to 100 Years, studying Prostate Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT05803941 trial and what does that mean for participants?

Phase 4 studies are conducted after a treatment has been approved. They monitor long-term safety and real-world effectiveness in a broader patient population.

Is NCT05803941 currently recruiting?

Yes, NCT05803941 is actively recruiting participants. Contact the research team at novartis.email@novartis.com for enrollment information.

Where is the NCT05803941 trial being conducted?

This trial is being conducted at Scottsdale, United States, Orange, United States, Santa Monica, United States, Aurora, United States and 11 additional locations.

Who is sponsoring the NCT05803941 clinical trial?

NCT05803941 is sponsored by Novartis Pharmaceuticals. The principal investigator is Novartis Pharmaceuticals at Novartis Pharmaceuticals. The trial plans to enroll 700 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology