State PA
Clinical Trials in Pennsylvania
Pennsylvania is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Pennsylvania and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 478 actively recruiting studies with Pennsylvania sites out of 478 registered in total. The busiest research areas in Pennsylvania are Prostate Cancer, Ovarian Cancer, Breast Cancer. Leading sponsors running trials in the state include University of Pennsylvania, University of Pittsburgh, Abramson Cancer Center at Penn Medicine. By stage, Pennsylvania trials break down as Phase 1 (82), Phase 2 (138), Phase 3 (101), Phase 4 (17).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Pennsylvania
Frequently Asked Questions — Clinical Trials in Pennsylvania
How many clinical trials are currently recruiting in Pennsylvania?
ClinicalMetric currently tracks 478 actively recruiting clinical trials with at least one location in Pennsylvania. The total number of registered studies—including active but not currently enrolling trials—is 478. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Pennsylvania?
Pennsylvania hosts clinical trials across a broad range of medical conditions, including Prostate Cancer, Ovarian Cancer, Breast Cancer, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Pennsylvania serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Pennsylvania?
To join a clinical trial in Pennsylvania, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Pennsylvania maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Pennsylvania
NCT06540976 N/A
Recruiting
Posterior Cingulate Cortex and Executive Control of Episodic Memory
Condition
Episodic Memory
Enrollment
130 pts
Location
United States
Sponsor
University of Pennsylvania
NCT05800574 Phase 2
Recruiting
Lymphoscintigraphy Directed Elective Neck Radiation for p16+ Favorable Risk Orop...
Condition
Oropharynx Cancer
Enrollment
22 pts
Location
United States
Sponsor
Fox Chase Cancer Center
NCT07339423 Phase 3
Recruiting
AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps...
Condition
Obesity
Enrollment
1,150 pts
Location
United States, Argentina, Australia
Sponsor
Novo Nordisk A/S
NCT06929455 N/A
Recruiting
Using Bitter Taste Receptor Blockers to Improve the Palatability of Pediatric Me...
Condition
Healthy Adults
Enrollment
100 pts
Location
United States
Sponsor
Monell Chemical Senses Center
NCT05443126 Phase 1, Phase 2
Recruiting
A Study of EP0031 (Lunbotinib) in Patients With Advanced RET-altered Malignancie...
Condition
NSCLC
Enrollment
265 pts
Location
United States, France, Germany
Sponsor
Ellipses Pharma
NCT03947385 Phase 1, Phase 2
Recruiting
Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRK...
Condition
Metastatic Uveal Melanoma
Enrollment
336 pts
Location
United States, Australia, Canada
Sponsor
IDEAYA Biosciences
NCT07086443 Phase 4
Recruiting
Randomized Evaluation of Nonhealing Diabetic Foot Ulcers With Exclusive Wound Th...
Condition
Diabetic Foot Ulcer
Enrollment
350 pts
Location
United States
Sponsor
Sequence LifeScience, Inc.
NCT06935591 N/A
Recruiting
Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Dr...
Condition
Atrial Fibrillation (AF)
Enrollment
423 pts
Location
United States, Germany
Sponsor
Vektor Medical
NCT06057935 Phase 2
Recruiting
A Study of Additional Chemotherapy After Surgery for People With Malignant Perit...
Condition
Malignant Peritoneal Mesothelioma
Enrollment
64 pts
Location
United States
Sponsor
Memorial Sloan Kettering Cance
NCT07224178 N/A
Recruiting
Left Atrial Strain and Cryptogenic Stroke
Condition
Ischemic Stroke, Cryptogenic
Enrollment
900 pts
Location
United States
Sponsor
University of Pittsburgh
NCT04372615 Phase 2
Recruiting
The ExTINGUISH Trial of Inebilizumab in NMDAR Encephalitis
Condition
Autoimmune Encephalitis
Enrollment
116 pts
Location
United States, Netherlands, Spain
Sponsor
University of Utah
NCT07086976 Phase 3
Recruiting
A Study to Investigate the Efficacy, Safety, and Pharmacokinetics of Oral Rilzab...
Condition
Autoimmune Haemolytic Anaemia
Enrollment
90 pts
Location
United States, Argentina, Austria
Sponsor
Sanofi
NCT05701917 N/A
Recruiting
DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombos...
Condition
Venous Thromboembolism
Enrollment
300 pts
Location
United States, Austria, Finland
Sponsor
Inari Medical
NCT07118358 N/A
Recruiting
BIOTRONIK Investigation of the LivIQ Leadless Pacemaker System
Condition
Leadless Pacemaker
Enrollment
325 pts
Location
United States, Australia, Austria
Sponsor
Biotronik, Inc.
NCT07710443 N/A
Recruiting
Safety and Effectiveness of Mosaic for the Treatment of Midface Volume Deficit
Condition
Midface Volume Deficit
Enrollment
50 pts
Location
United States
Sponsor
Helios Aesthetics Inc.
NCT05139017 Phase 2, Phase 3
Recruiting
A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care i...
Condition
DLBCL
Enrollment
290 pts
Location
United States, Argentina, Australia
Sponsor
Merck Sharp & Dohme LLC
NCT07001293 N/A
Recruiting
Expectant Moms Managing Attention-Deficit/ Hyperactivity Disorder
Condition
ADHD
Enrollment
80 pts
Location
United States
Sponsor
University of Pittsburgh
NCT07908979 Phase 2
Recruiting
Risk-Enabled Therapy After Initiating EV/Pembro for Bladder Cancer
Condition
Bladder Cancer
Enrollment
70 pts
Location
United States
Sponsor
Fox Chase Cancer Center
NCT07629440 Phase 3
Recruiting
A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.
Condition
Pneumococcal Disease
Enrollment
3,230 pts
Location
United States, Japan, Puerto Rico
Sponsor
Pfizer
NCT03373968 Phase 2, Phase 3
Recruiting
Givinostat in Duchenne's Muscular Dystrophy Long-term Safety and Tolerability St...
Condition
Duchenne Muscular Dystrophy
Enrollment
206 pts
Location
United States, Belgium, Canada
Sponsor
Italfarmaco
NCT05641935 Phase 2
Recruiting
Contrast-Enhanced Ultrasound Imaging for Diagnosing Recurrent Renal Cell Carcino...
Condition
Recurrent Renal Cell Carcinoma
Enrollment
210 pts
Location
United States
Sponsor
john eisenbrey
NCT07322913 N/A
Recruiting
Intervascular Post-Market Clinical Follow-Up (PMCF) Registry
Condition
Carotid Artery Diseases
Enrollment
1,200 pts
Location
United States, Belgium, France
Sponsor
Intervascular
NCT06576323 N/A
Recruiting
An Intervention Mapping Approach to Closing the Gap in Maternal OUD and Infant N...
Condition
Opioid Use Disorder
Enrollment
50 pts
Location
United States
Sponsor
University of Pennsylvania
NCT06222580 Phase 1
Recruiting
SNDX-5613 and Gilteritinib for the Treatment of Relapsed or Refractory FLT3-Muta...
Condition
Acute Myeloid Leukemia With FLT3/ITD Mutation
Enrollment
30 pts
Location
United States
Sponsor
Uma Borate
NCT06832189 Phase 1
Recruiting
EVR and EPO for Liver Transplant Tolerance
Condition
Liver Transplant
Enrollment
20 pts
Location
United States
Sponsor
National Institute of Allergy
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology