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Medical Condition
acute myeloid leukemia
Total Trials
38
Recruiting Now
38
Trial Phases
Phase 2, Phase 3, Phase 1
NCT04195633 Phase 2
Recruiting
Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies
Enrollment
60 pts
Location
United States
Sponsor
Fred Hutchinson Cancer Center
NCT04168502 Phase 3
Recruiting
Gemtuzumab Chemotherapy MRD Levels; Adult Untreated, de Novo, Fav Interm Risk AML
Enrollment
414 pts
Location
Italy
Sponsor
Gruppo Italiano Malattie EMato...
NCT05875805
Recruiting
A Telehealth Advance Care Planning Intervention
Enrollment
207 pts
Location
United States
Sponsor
University of Rochester
NCT06713837 Phase 3
Recruiting
IMPACT-AML: A Randomized Pragmatic Clinical Trial for Relapsed or Refractory Acute Myeloid Leukemia.
Enrollment
339 pts
Location
Czechia, Germany, It...
Sponsor
Istituto Romagnolo per lo Stud...
NCT05031897 Phase 2
Recruiting
Two Step Haplo With Radiation Conditioning
Enrollment
63 pts
Location
United States
Sponsor
Thomas Jefferson University
NCT06440135 Phase 1
Recruiting
Ziftomenib Maintenance Post Allo-HCT
Enrollment
22 pts
Location
United States
Sponsor
Massachusetts General Hospital
NCT03471260 Phase 1, Phase 2
Recruiting
Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignancies
Enrollment
96 pts
Location
United States
Sponsor
M.D. Anderson Cancer Center
NCT06195891 Phase 1
Recruiting
Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrome
Enrollment
33 pts
Location
United States
Sponsor
City of Hope Medical Center
NCT06328179
Recruiting
Clinical Study Protocol for the Treatment of ND-AML and RR-AML With KMT2A Gene Abnormalities Using VHEA.
Enrollment
34 pts
Location
China
Sponsor
Huai'an First People's Hospita...
NCT06575296 Phase 1
Recruiting
Revumenib for the Treatment of Acute Leukemia in Patients Post-Allogeneic Stem Cell Transplant
Enrollment
27 pts
Location
United States
Sponsor
City of Hope Medical Center
NCT05334069
Recruiting
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
Enrollment
2,000 pts
Location
United States
Sponsor
Alliance for Clinical Trials i...
NCT05184842 Phase 2
Recruiting
Metabolically Optimized, Non-cytotoxic Low Dose Weekly Decitabine/Venetoclax in MDS and AML
Enrollment
91 pts
Location
United States
Sponsor
Montefiore Medical Center
NCT07356154 Phase 1, Phase 2
Recruiting
A Study of Revumenib and Mezigdomide in People With Leukemia
Enrollment
52 pts
Location
United States
Sponsor
Memorial Sloan Kettering Cance...
NCT05401097 Phase 2
Recruiting
IDH Targeted/Non- Targeted vs Non-targeted/IDH-targeted Approaches in the Treatment of Newly Diagnosed IDH Mutated AML Patients Not Candidates for Intensive Induction Therapy (I- DATA Study)
Enrollment
125 pts
Location
United States
Sponsor
Alice Mims
NCT06928662 Phase 1, Phase 2
Recruiting
Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse
Enrollment
36 pts
Location
United States
Sponsor
Fred Hutchinson Cancer Center
NCT06651866 Phase 1
Recruiting
Dose-escalation Study of D-CMG Regimen for the Treatment of Elderly Newly Diagnosed AML Patients
Enrollment
18 pts
Location
China
Sponsor
The First Affiliated Hospital ...
NCT05101551 Phase 1
Recruiting
Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy
Enrollment
34 pts
Location
United States
Sponsor
Norman J. Lacayo
NCT05995028 Phase 1
Recruiting
Universal 4SCAR7U Targeting CD7-positive Malignancies
Enrollment
30 pts
Location
China
Sponsor
Shenzhen Geno-Immune Medical I...
NCT04662294 EARLY_Phase 1
Recruiting
CD 70 CAR T for Patients With CD70 Positive Malignant Hematologic Diseases
Enrollment
108 pts
Location
China
Sponsor
Zhejiang University
NCT04293562 Phase 3
Recruiting
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations
Enrollment
1,186 pts
Location
United States, Austr...
Sponsor
Children's Oncology Group
NCT06386302
Recruiting
Chidamide, Venetoclax, and Azacitidine for Newly Diagnosed Acute Myeloid Leukemia
Enrollment
184 pts
Location
China
Sponsor
Institute of Hematology & Bloo...
NCT06737523 Phase 1
Recruiting
Chiglitazar Sodium Combined With Venetoclax and Azacitidine (CVA) for the Treatment of R/R AML
Enrollment
30 pts
Location
China
Sponsor
The First Affiliated Hospital ...
NCT06514261 Phase 1
Recruiting
Testing the Combination of an Anti-Cancer Drug, Iadademstat, With Other Anti-Cancer Drugs (Venetoclax and Azacitidine) for Treating AML
Enrollment
45 pts
Location
United States
Sponsor
National Cancer Institute (NCI...
NCT06297941 Phase 1
Recruiting
Study of REM-422 in Patients With AML or Higher Risk MDS
Enrollment
100 pts
Location
United States, Franc...
Sponsor
Remix Therapeutics
NCT06880354 Phase 1
Recruiting
A Clinical Study to Evaluate the Safety and Efficacy of CLL1 and CD38 Dual-Target CAR-T Cell Injection in the Treatment of Relapsed or Refractory Acute Myeloid Leukemia
Enrollment
37 pts
Location
China
Sponsor
Institute of Hematology & Bloo...
NCT06221683 Phase 2
Recruiting
Clinical Study of Induction Therapy Options Based on Molecular Subtyping and MRD in Children and Adolescents With AML
Enrollment
500 pts
Location
China
Sponsor
Children's Hospital of Soochow...
NCT06824168 Phase 2
Recruiting
Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission
Enrollment
130 pts
Location
United States, Austr...
Sponsor
Daiichi Sankyo
NCT03589729 Phase 2
Recruiting
Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers
Enrollment
100 pts
Location
United States
Sponsor
M.D. Anderson Cancer Center
NCT06389292 Phase 3
Recruiting
A Pivotal Study of APG-2575 (Lisaftoclax) Combined With Azacitidine in the Treatment of Acute Myeloid Leukemia
Enrollment
486 pts
Location
China, Russia
Sponsor
Ascentage Pharma Group Inc.
NCT06111612
Recruiting
Intensive Conditioning withTHI/Bu/Flu/Ara-C in Allo-HSCT for Myeloid Malignancies With Extramedullary Involvement
Enrollment
50 pts
Location
China
Sponsor
Shanghai General Hospital, Sha...
NCT06594445 Phase 1
Recruiting
HM2023-05: GTB-3650 Trike for High Risk MDS and R/R AML
Enrollment
45 pts
Location
United States
Sponsor
Masonic Cancer Center, Univers...
NCT02115295 Phase 2
Recruiting
Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia
Enrollment
508 pts
Location
United States
Sponsor
M.D. Anderson Cancer Center
NCT06458257
Recruiting
The Efficacy of Allogeneic Hematopoietic Stem Cell Transplantation in Newly Diagnosed High-relapse-risk CEBPA Mutant Acute Myeloid Leukemia
Enrollment
50 pts
Location
China
Sponsor
Ruijin Hospital
NCT05834244 Phase 1
Recruiting
A Phase Ib Trial of Azacitidine, Venetoclax and Allogeneic NK Cells for Acute Myeloid Leukemia (ADVENT-AML)
Enrollment
32 pts
Location
United States
Sponsor
M.D. Anderson Cancer Center
NCT04953897 Phase 1
Recruiting
Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Renal Impairment
Enrollment
18 pts
Location
United States, Armen...
Sponsor
Taiho Oncology, Inc.
NCT04811560 Phase 1, Phase 2
Recruiting
A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)
Enrollment
400 pts
Location
United States, Austr...
Sponsor
Janssen Research & Development...
NCT07321626 Phase 1
Recruiting
Romiplostim N01 for Platelet Recovery After Haploidentical HSCT
Enrollment
130 pts
Location
China
Sponsor
First Affiliated Hospital of Z...
NCT03113643 Phase 1
Recruiting
SL-401 in Combination With Azacitidine or Azacitidine/Venetoclax in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
Enrollment
72 pts
Location
United States
Sponsor
Dana-Farber Cancer Institute