State PA
Clinical Trials in Pennsylvania
Pennsylvania is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Pennsylvania and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 483 actively recruiting studies with Pennsylvania sites out of 483 registered in total. The busiest research areas in Pennsylvania are Breast Cancer, Endometrial Cancer, Ovarian Cancer. Leading sponsors running trials in the state include University of Pennsylvania, University of Pittsburgh, AstraZeneca. By stage, Pennsylvania trials break down as Phase 1 (84), Phase 2 (142), Phase 3 (117), Phase 4 (16).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Pennsylvania
Frequently Asked Questions — Clinical Trials in Pennsylvania
How many clinical trials are currently recruiting in Pennsylvania?
ClinicalMetric currently tracks 483 actively recruiting clinical trials with at least one location in Pennsylvania. The total number of registered studies—including active but not currently enrolling trials—is 483. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Pennsylvania?
Pennsylvania hosts clinical trials across a broad range of medical conditions, including Breast Cancer, Endometrial Cancer, Ovarian Cancer, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Pennsylvania serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Pennsylvania?
To join a clinical trial in Pennsylvania, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Pennsylvania maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Pennsylvania
NCT07089602 Phase 4
Recruiting
Trial Assessing the Efficacy of Human Placental Membrane Products and Standard o...
Condition
Diabetic Foot
Enrollment
650 pts
Location
United States
Sponsor
BioLab Holdings
NCT06152575 Phase 3
Recruiting
MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in P...
Condition
Multiple Myeloma
Enrollment
492 pts
Location
United States, Argentina, Australia
Sponsor
Pfizer
NCT06896188 Phase 1
Recruiting
9-ING-41 Combined With Retifanlimab, Plus Modified FOLFIRINOX for Patients With ...
Condition
Pancreatic Adenocarcinoma
Enrollment
12 pts
Location
United States
Sponsor
Anwaar Saeed
NCT06455969 Phase 4
Recruiting
Adaptions and Resiliency to Multi-Stressor OpeRations
Condition
Musculoskeletal Injury
Enrollment
120 pts
Location
United States
Sponsor
Bradley Nindl
NCT07574645 N/A
Recruiting
Spinal Dural Arteriovenous Fistula International Data and Outcomes Registry
Condition
Spinal Dural Arteriovenous Fistula
Enrollment
1,000 pts
Location
United States
Sponsor
Thomas Jefferson University
NCT05470205 Phase 3
Recruiting
Noninvasive Subharmonic Aided Pressure Estimation of Portal Hypertension; Renewa...
Condition
Liver Diseases
Enrollment
660 pts
Location
United States, Switzerland
Sponsor
Thomas Jefferson University
NCT04291612 N/A
Recruiting
Observational Study of Women With Endometrial Cancer Who Receive the Standard Tr...
Condition
Endometrial Cancer
Enrollment
1,715 pts
Location
United States, Czechia, Italy
Sponsor
Memorial Sloan Kettering Cance
NCT04731272 Phase 2
Recruiting
GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance
Condition
Cystic Fibrosis
Enrollment
30 pts
Location
United States
Sponsor
University of Pennsylvania
NCT06624670 Phase 3
Recruiting
A Study to Test Whether Spesolimab Helps People With a Skin Condition Called Pyo...
Condition
Pyoderma Gangrenosum
Enrollment
90 pts
Location
United States, Argentina, Australia
Sponsor
LEO Pharma
NCT07266805 Phase 3
Recruiting
Study of Oral Deucrictibant XR Tablet for Prophylaxis and Deucrictibant IR Capsu...
Condition
Acquired Angioedema Due to C1-Inhibitor Deficiency (AAE-C1-INH)
Enrollment
32 pts
Location
United States, Australia, Austria
Sponsor
Pharvaris Netherlands B.V.
NCT06559995 Phase 2, Phase 3
Recruiting
Effects of Ketone Supplementation on Alcohol Withdrawal and Brain Metabolism in ...
Condition
Alcohol Use Disorder
Enrollment
30 pts
Location
United States
Sponsor
University of Pennsylvania
NCT04720456 Phase 2
Recruiting
SHAPE of Portal Hypertension in Children
Condition
Hypertension, Portal
Enrollment
120 pts
Location
United States
Sponsor
Thomas Jefferson University
NCT06324357 Phase 1, Phase 2
Recruiting
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in...
Condition
Metastatic Breast Cancer
Enrollment
768 pts
Location
United States, Belgium, China
Sponsor
Boehringer Ingelheim
NCT06085092 N/A
Recruiting
Open vs. Blind Weighing Study In Adolescents and Young Adult With Eating Disorde...
Condition
Eating Disorders
Enrollment
70 pts
Location
United States
Sponsor
Milton S. Hershey Medical Cent
NCT05076175 Phase 2, Phase 3
Recruiting
A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Mod...
Condition
Colitis, Ulcerative
Enrollment
120 pts
Location
United States, Australia, Belgium
Sponsor
Bristol-Myers Squibb
NCT07332975 N/A
Recruiting
ctDNA Positive Patients Diagnosed With cT1bN0 and cT1cN0 TNBC
Condition
Triple Negative Breast Cancer
Enrollment
77 pts
Location
United States
Sponsor
University of Pittsburgh
NCT05519475 Phase 2
Recruiting
A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Dise...
Condition
Metabolic Dysfunction-Associated SteatoHepatitis (MASH)
Enrollment
120 pts
Location
United States, Japan, Puerto Rico
Sponsor
Regeneron Pharmaceuticals
NCT06095128 Phase 4
Recruiting
A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
Condition
Ulcerative Colitis
Enrollment
65 pts
Location
United States, Canada
Sponsor
Takeda
NCT05313165 N/A
Recruiting
PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-St...
Condition
Critical Limb Ischemia
Enrollment
100 pts
Location
United States
Sponsor
LimFlow, Inc.
NCT07271667 Phase 2
Recruiting
A Study of Emavusertib + An Approved Bruton Tyrosine Kinase Inhibitor (BTKi) in ...
Condition
Chronic Lymphocytic Leukemia
Enrollment
108 pts
Location
United States, Italy, Spain
Sponsor
Curis, Inc.
NCT06134167 N/A
Recruiting
Transdermal Compress IDE Study
Condition
Prosthesis and Implants
Enrollment
100 pts
Location
United States
Sponsor
Balmoral Medical company
NCT06458036 Phase 2
Recruiting
Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)
Condition
Differentiated Thyroid Cancer
Enrollment
13 pts
Location
United States
Sponsor
Children's Hospital of Philade
NCT07016971 Phase 1
Recruiting
CBG/CBD Oil for Chemotherapy-Induced Peripheral Neuropathy
Condition
Chemotherapy-Induced Peripheral Neuropathy
Enrollment
12 pts
Location
United States
Sponsor
Milton S. Hershey Medical Cent
NCT05071937 Phase 2
Recruiting
ZEN003694 Combined With Talazoparib in Patients With Recurrent Ovarian Cancer
Condition
Ovarian Cancer
Enrollment
33 pts
Location
United States
Sponsor
Alexander B Olawaiye, MD
NCT06699212 Phase 3
Recruiting
A Study of ASP-1929 Photoimmunotherapy in Combination With Pembrolizumab in Firs...
Condition
Recurrent Head and Neck Squamous Cell Carcinoma
Enrollment
412 pts
Location
United States, Japan, Taiwan
Sponsor
Rakuten Medical, Inc.
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology