State PA
Clinical Trials in Pennsylvania
Pennsylvania is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Pennsylvania and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 478 actively recruiting studies with Pennsylvania sites out of 478 registered in total. The busiest research areas in Pennsylvania are Prostate Cancer, Ovarian Cancer, Breast Cancer. Leading sponsors running trials in the state include University of Pennsylvania, University of Pittsburgh, Abramson Cancer Center at Penn Medicine. By stage, Pennsylvania trials break down as Phase 1 (82), Phase 2 (138), Phase 3 (101), Phase 4 (17).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Pennsylvania
Frequently Asked Questions — Clinical Trials in Pennsylvania
How many clinical trials are currently recruiting in Pennsylvania?
ClinicalMetric currently tracks 478 actively recruiting clinical trials with at least one location in Pennsylvania. The total number of registered studies—including active but not currently enrolling trials—is 478. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Pennsylvania?
Pennsylvania hosts clinical trials across a broad range of medical conditions, including Prostate Cancer, Ovarian Cancer, Breast Cancer, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Pennsylvania serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Pennsylvania?
To join a clinical trial in Pennsylvania, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Pennsylvania maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Pennsylvania
NCT04503395 N/A
Recruiting
ShOrt neCK AAA RAndomized Trial - ESAR and FEVAR: SOCRATES
Condition
Aortic Aneurysm, Abdominal
Enrollment
204 pts
Location
United States, Austria, Belgium
Sponsor
FCRE (Foundation for Cardiovas
NCT06619444 N/A
Recruiting
Dose-Response to Resistance Exercise on Cardiovascular Health
Condition
Cardiovascular Risk
Enrollment
240 pts
Location
United States
Sponsor
University of Pittsburgh
NCT05616793 Phase 1, Phase 2
Recruiting
Safety and Tolerability Subretinal OPGx-001 for LCA5-Associated Inherited Retina...
Condition
LCA5
Enrollment
22 pts
Location
United States
Sponsor
Opus Genetics, Inc
NCT04638647 Phase 4
Recruiting
Secukinumab Open Label Roll-over Extension Protocol
Condition
Autoimmunity, Inflammation
Enrollment
1,000 pts
Location
United States, Belgium, Brazil
Sponsor
Novartis Pharmaceuticals
NCT05977348 N/A
Recruiting
Increasing Food Literacy in Preschoolers to Reduce Obesity Risk
Condition
Food Preferences
Enrollment
770 pts
Location
United States
Sponsor
Penn State University
NCT04434040 Phase 2
Recruiting
Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)
Condition
Breast Cancer
Enrollment
40 pts
Location
United States
Sponsor
Dana-Farber Cancer Institute
NCT05826535 Phase 1, Phase 2
Recruiting
Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma
Condition
Relapsed Non-Hodgkin Lymphoma
Enrollment
270 pts
Location
United States, Australia
Sponsor
Lyell Immunopharma, Inc.
NCT06379789 Phase 1, Phase 2
Recruiting
A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX G...
Condition
Hemophilia B
Enrollment
130 pts
Location
United States, Australia, Brazil
Sponsor
Regeneron Pharmaceuticals
NCT07222891 Phase 2
Recruiting
Impact of Smell Testing on Health Outcomes
Condition
Olfactory Dysfunction
Enrollment
1,000 pts
Location
United States
Sponsor
Monell Chemical Senses Center
NCT07573176 Phase 3
Recruiting
A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Ma...
Condition
Depressive Disorder, Major
Enrollment
600 pts
Location
United States, Argentina, Brazil
Sponsor
Janssen Research & Development
NCT04920617 Phase 2
Recruiting
DPX-Survivac and Pembrolizumab With and Without Intermittent Low-Dose Cyclophosp...
Condition
Relapsed Diffuse Large B-cell Lymphoma
Enrollment
102 pts
Location
United States, Australia, Canada
Sponsor
ImmunoVaccine Technologies, In
NCT07358078 N/A
Recruiting
DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients ...
Condition
Transthyretin Amyloidosis With Cardiomyopathy
Enrollment
2,000 pts
Location
United States, Germany, Japan
Sponsor
Alnylam Pharmaceuticals
NCT06844227 N/A
Recruiting
Perioperative Anticoagulant Use for Surgery Evaluation -Virtual Visit (PAUSE-Vir...
Condition
Atrial Fibrillation (AF)
Enrollment
1,780 pts
Location
United States, Canada, Greece
Sponsor
McMaster University
NCT06636383 N/A
Recruiting
Glycogen Storage Disease Type Ia (GSDIa) Disease Monitoring Program
Condition
Glycogen Storage Disease Type Ia
Enrollment
140 pts
Location
United States, Brazil, Canada
Sponsor
Ultragenyx Pharmaceutical Inc
NCT05625659 N/A
Recruiting
Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breas...
Condition
Breast Cancer
Enrollment
2,032 pts
Location
United States, Canada
Sponsor
American College of Radiology
NCT07132788 N/A
Recruiting
Understanding the Effects of Pulmonary Arterial Hypertension on Lean Muscle Mass
Condition
Pulmonary Hypertension
Enrollment
150 pts
Location
United States
Sponsor
University of Pennsylvania
NCT07216027 Phase 2
Recruiting
A Study to Learn About Study Medicine Called PF-08049820 in People With Eczema
Condition
Atopic Dermatitis
Enrollment
165 pts
Location
United States, Bulgaria, Canada
Sponsor
Pfizer
NCT06613841 EARLY_Phase 1
Recruiting
Multitracer [18F]Fluciclovine and 18F-FDG PET, and Advanced MRI for Metabolic Pr...
Condition
Glioblastoma
Enrollment
15 pts
Location
United States
Sponsor
Abramson Cancer Center at Penn
NCT07174388 N/A
Recruiting
An External Control Arm Study in Non-Small Cell Lung Cancer
Condition
Non Small Cell Lung Cancer
Enrollment
650 pts
Location
United States
Sponsor
N-Power Medicine
NCT07369154 Phase 3
Recruiting
52-week Open Label Safety-Tolerability Study
Condition
Schizophrenia
Enrollment
900 pts
Location
United States
Sponsor
LB Pharmaceuticals Inc.
NCT07064005 Phase 1
Recruiting
Enrichment of Glutathione Using Gamma-glutamylcysteine Supplementation in Parkin...
Condition
Parkinsons Disease (PD)
Enrollment
12 pts
Location
United States
Sponsor
Pravat Mandal
NCT07050173 Phase 1
Recruiting
Monitoring Patients With Repetitive Head Impact With Gamma-glutamylcysteine Supp...
Condition
Repetitive Head Impacts
Enrollment
30 pts
Location
United States
Sponsor
Pravat Mandal
NCT05748366 N/A
Recruiting
Ultrasound Guided Serratus Anterior Plane Block for Rib Fractures
Condition
Rib Fracture Multiple
Enrollment
60 pts
Location
United States
Sponsor
WellSpan Health
NCT07056361 N/A
Recruiting
Stimulating Specific Brain Areas (VOP/VIM) With Electricity to Improve Movement ...
Condition
Movement Disorders (Incl Parkinsonism)
Enrollment
60 pts
Location
United States
Sponsor
Jorge Gonzalez-Martinez
NCT00001373 N/A
Recruiting
Familial Mediterranean Fever and Related Disorders: Genetics and Disease Charact...
Condition
Familial Mediterranean Fever (FMF)
Enrollment
5,000 pts
Location
United States
Sponsor
National Human Genome Research
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology