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lymphoma

Total Trials
34
Recruiting Now
34
Trial Phases
Phase 1, Phase 3, Phase 2

Lymphoma trials span diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, Hodgkin lymphoma, mantle cell lymphoma, and T-cell lymphomas β€” each with distinct biology and treatment response. CAR-T cell therapy has established a new standard in relapsed/refractory DLBCL, and trials now aim to move this approach earlier in the treatment sequence.

Active trials evaluate bispecific antibodies (mosunetuzumab, epcoritamab, glofitamab), next-generation CAR-T cell products (CD19/CD22 dual targets, BCMA-targeting), BTK inhibitors in B-cell lymphomas, and total metabolic volume on PET as a predictive biomarker for treatment adaptation.

Frequently Asked Questions — lymphoma Clinical Trials

How many clinical trials are currently recruiting for lymphoma?
ClinicalMetric currently tracks 34 actively recruiting clinical trials for lymphoma, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 34. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for lymphoma?
lymphoma research spans Phase 1 (4 trials), Phase 2 (6 trials), Phase 3 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a lymphoma clinical trial?
Eligibility criteria for lymphoma trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
4
Phase 2
6
Phase 3
1
Top Sponsors
Memorial Sloan Kettering Cancer Center 5 trials
Dana-Farber Cancer Institute 2 trials
The Affiliated People's Hospital of Ningbo University 1 trial
Norwegian School of Sport Sciences 1 trial
Bnai Zion Medical Center 1 trial

Recruiting Clinical Trials

NCT05528887 Phase 1
Recruiting
Study of CAR-T Cell Therapy in the Treatment of Relapsed/Refractory Hematological Malignancies
Enrollment
10 pts
Location
China
Sponsor
The Affiliated People's Hospit...
View Trial →
NCT06270667
Recruiting
Effects of Exercise Training in Survivors of Lymphoma
Enrollment
280 pts
Location
Norway, Sweden
Sponsor
Norwegian School of Sport Scie...
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NCT05982223
Recruiting
Integrative Medicine in Lymphoma Survivors
Enrollment
90 pts
Location
Israel
Sponsor
Bnai Zion Medical Center
View Trial →
NCT07205523
Recruiting
High-Altitude Hematology Observation-Stem Cell Transplantation (HALO-SCT)
Enrollment
1,000 pts
Location
China
Sponsor
Yigeng Cao,MD,PhD
View Trial →
NCT06236373
Recruiting
The Unmet Needs of Cancer Survivors in Ausl IRCCS Reggio Emilia
Enrollment
45 pts
Location
Italy
Sponsor
University of Modena and Reggi...
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NCT06084936 Phase 3
Recruiting
A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma
Enrollment
182 pts
Location
United States, Austr...
Sponsor
Hoffmann-La Roche
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NCT07226934
Recruiting
An AI-Generated, Personalized Question Prompt List Intervention for Patients With Hematologic Cancers
Enrollment
40 pts
Location
United States
Sponsor
Washington University School o...
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NCT02595255
Recruiting
AMH as a Predictor of Infertility Risk in Children With Cancer (CHANCE)
Enrollment
275 pts
Location
Belgium, France
Sponsor
Erasme University Hospital
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NCT05891821 Phase 2
Recruiting
Assessment of the Safety and Efficacy of Balstilimab for the Treatment of Relapsed/Refractory Lymphomas (IMMONC0001)
Enrollment
20 pts
Location
Armenia
Sponsor
Immune Oncology Research Insti...
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NCT07138547 Phase 1, Phase 2
Recruiting
GSL Synthetase Inhibitor Eliglustat Combined With CD30 Target Immunotherapy for the Treatment of of CD30+ Lymphoma
Enrollment
40 pts
Location
China
Sponsor
Chinese PLA General Hospital
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NCT05702502
Recruiting
Assessing the Presence of CT-DNA in Lymphoma Associated HLH
Enrollment
12 pts
Location
United Kingdom
Sponsor
Nottingham University Hospital...
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NCT06475235 Phase 1
Recruiting
Pembrolizumab + Chemotherapy in Newly Diagnosed PCNSL
Enrollment
15 pts
Location
United States
Sponsor
Dana-Farber Cancer Institute
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NCT01441089
Recruiting
Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis
Enrollment
1,100 pts
Location
United States
Sponsor
National Cancer Institute (NCI...
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NCT06915246 Phase 2
Recruiting
A Study of Carmustine With and Without Ethanol in Subjects With Lymphoma
Enrollment
49 pts
Location
United States
Sponsor
VIVUS LLC
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NCT05388838
Recruiting
Screening for Oculocerebral Lymphoma with the Phenotype of NK Cells in Patients with Uveitis
Enrollment
60 pts
Location
France
Sponsor
Hospices Civils de Lyon
View Trial →
NCT06795815
Recruiting
The Implementation of the Go Wish Game to Promote Advance Care Planning in Onco- Hematologic Disease
Enrollment
75 pts
Location
Italy
Sponsor
Azienda USL Reggio Emilia - IR...
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NCT04053439
Recruiting
Clonal Hematopoiesis is a Risk Factor for Chemotherapy-Related Complications
Enrollment
188 pts
Location
Canada
Sponsor
Sunnybrook Health Sciences Cen...
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NCT05940272
Recruiting
Study of a Communication Training Intervention for Large B-Cell Lymphoma Providers
Enrollment
48 pts
Location
United States
Sponsor
Memorial Sloan Kettering Cance...
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NCT07566377 Phase 2
Recruiting
Cord Blood Transplantation in Children and Young Adults With Blood Cancer
Enrollment
71 pts
Location
United States
Sponsor
Memorial Sloan Kettering Cance...
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NCT01788839
Recruiting
Longitudinal Sexual and Reproductive Health Study of Women With Breast Cancer and Lymphoma
Enrollment
475 pts
Location
United States
Sponsor
Memorial Sloan Kettering Cance...
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NCT06347939
Recruiting
Mediastinal EBUS Cryobiopsy Study In Sweden
Enrollment
200 pts
Location
Sweden
Sponsor
Region Skane
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NCT07082803 Phase 1
Recruiting
TLN-121 in Relapsed or Refractory Non-Hodgkin Lymphomas
Enrollment
180 pts
Location
United States, Austr...
Sponsor
Treeline Biosciences, Inc.
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NCT00935090
Recruiting
3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer
Location
United States
Sponsor
Barbara Ann Karmanos Cancer In...
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NCT06774326
Recruiting
Role of Spectral CT in the Evaluation of Cardiotoxicity in Patients With Hodgkin's Lymphoma and Diffuse Large B-cell Lymphoma Treated With Anthracyclines
Enrollment
160 pts
Location
Italy
Sponsor
IRCCS Azienda Ospedaliero-Univ...
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NCT04957901
Recruiting
The Value of Monitoring Circulating Cell DNA (ctDNA) in Pediatric Lymphoma: A Prospective, Multicenter Clinical Study
Enrollment
60 pts
Location
China
Sponsor
Sun Yat-sen University
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NCT04645199
Recruiting
National Longitudinal Cohort of Hematological Diseases
Enrollment
2,300 pts
Location
China
Sponsor
Institute of Hematology & Bloo...
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NCT06131801
Recruiting
Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution
Enrollment
30 pts
Location
United States
Sponsor
Children's Hospital Medical Ce...
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NCT03702309
Recruiting
Liquid Biopsy Evaluation and Repository Development at Princess Margaret
Enrollment
2,500 pts
Location
Canada
Sponsor
University Health Network, Tor...
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NCT07167381
Recruiting
xDRIVE for Florida-based Cancer Patients
Enrollment
210 pts
Location
United States
Sponsor
First Ascent Biomedical Inc.
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NCT07052916
Recruiting
A Music Therapy Study for Blood Cancer Survivors With Cognitive Difficulties
Enrollment
60 pts
Location
United States
Sponsor
Memorial Sloan Kettering Cance...
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NCT02974647 Phase 2
Recruiting
Study of Ruxolitinib in Relapsed or Refractory T or NK Cell Lymphoma
Enrollment
83 pts
Location
United States
Sponsor
Memorial Sloan Kettering Cance...
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NCT06487247
Recruiting
HEME Home Transfusion Program
Enrollment
700 pts
Location
United States
Sponsor
Dana-Farber Cancer Institute
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NCT07058064
Recruiting
WATCH (Wearable Artificial inTelligence for Cardiac Function and Health Monitoring)
Enrollment
250 pts
Location
United States
Sponsor
Mayo Clinic
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NCT06852638 Phase 2
Recruiting
CD70-targeted immunoPET Imaging of Malignant Cancers
Enrollment
300 pts
Location
China
Sponsor
RenJi Hospital
View Trial →

Related Conditions

leukemia (10) myeloma (4) multiple myeloma (4) breast cancer (4) cancer (3) lung cancer (3) non hodgkin lymphoma (3) hodgkin lymphoma (3) myelodysplastic syndromes (3) chemotherapeutic toxicity (2) hemophilia (2) myelodysplastic syndrome (2)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology