← Browse by Condition
Medical Condition

coronary artery disease

Total Trials
57
Recruiting Now
57
Trial Phases
Phase 4, Phase 3, Phase 2, Phase 3

ClinicalMetric tracks all active clinical trials for coronary artery disease sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — coronary artery disease Clinical Trials

How many clinical trials are currently recruiting for coronary artery disease?
ClinicalMetric currently tracks 57 actively recruiting clinical trials for coronary artery disease, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 57. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for coronary artery disease?
coronary artery disease research spans Phase 2 (1 trial), Phase 3 (3 trials), Phase 4 (6 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a coronary artery disease clinical trial?
Eligibility criteria for coronary artery disease trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 2
1
Phase 3
3
Phase 4
6
Top Sponsors
Shanghai Zhongshan Hospital 3 trials
University of Calgary 2 trials
Centro Cardiologico Monzino 2 trials
Peking Union Medical College Hospital 2 trials
Second Affiliated Hospital, Zhejiang University, School of Medicine 2 trials

Recruiting Clinical Trials

NCT07039812
Recruiting
The Effect of Virtual Reality and Eye Mask During Dressing After CABG Surgery
Enrollment
90 pts
Location
Turkey (Türkiye)
Sponsor
Istanbul University - Cerrahpa...
View Trial →
NCT07068399
Recruiting
Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronary Artery Disease: Validation by Quantitative Cardiac MRI Perfusion
Enrollment
100 pts
Location
Hong Kong
Sponsor
The University of Hong Kong
View Trial →
NCT07609381
Recruiting
Clinical Information System Impact on Hospitalized Patients With Chronic Disease
Enrollment
124,240 pts
Location
Canada
Sponsor
University of Calgary
View Trial →
NCT07116083
Recruiting
µQFR for Branch Stenosis After Single Stent in Bifurcation Lesions
Enrollment
290 pts
Location
China
Sponsor
Shanghai Zhongshan Hospital
View Trial →
NCT06920927
Recruiting
Feasibility and Pilot Testing of "My Heart and CKD" Online Shared Decision Aid
Enrollment
220 pts
Location
Canada
Sponsor
University of Calgary
View Trial →
NCT06410690
Recruiting
Trustworthy, Integrated Artificial Intelligence Tools for Predicting High-risk CORonary PlaqueS
Enrollment
4,000 pts
Location
Italy
Sponsor
Centro Cardiologico Monzino
View Trial →
NCT04014803 Phase 4
Recruiting
Aspirin and a PoTent P2Y12 Inhibitor Versus Aspirin and Clopidogrel in Patients Undergoing PCI for Complex Lesion
Enrollment
3,500 pts
Location
South Korea
Sponsor
Samsung Medical Center
View Trial →
NCT07198529
Recruiting
OCT-Guided Stent Optimization for Short-Duration Dual Antiplatelet Therapy in Stable Angina
Enrollment
130 pts
Location
South Korea
Sponsor
Korea University Guro Hospital
View Trial →
NCT07498231
Recruiting
COronoary Microcirculation Analysis NETwork
Enrollment
180 pts
Location
Poland
Sponsor
Medical University of Bialysto...
View Trial →
NCT06845410
Recruiting
Clinical Features, Current Treatment and Clinical Outcomes in Patients With INR-CAD: a Cohort Study
Enrollment
120 pts
Location
China
Sponsor
Peking Union Medical College H...
View Trial →
NCT05081115
Recruiting
Stress Echo 2030: the Novel ABCDE-(FGLPR) Protocol to Define the Future of Imaging
Enrollment
10,000 pts
Location
Italy
Sponsor
Fatebenefratelli Hospital
View Trial →
NCT07846462
Recruiting
Aspirin 50mg vs 100mg Combined With P2Y12 Inhibitor After PCI
Enrollment
2,640 pts
Location
China
Sponsor
Jilin University
View Trial →
NCT07566091
Recruiting
Noninferiority Trial Of Sirolimus With Ascorbic Acid Versus Everolimus in All-comers
Enrollment
2,034 pts
Location
South Korea
Sponsor
Jung-min Ahn
View Trial →
NCT07811024
Recruiting
First-in-Human Study Using the SiroMax™ Sirolimus-Coated Balloon Catheter as a Percutaneous Transluminal Coronary Angioplasty (PTCA) Balloon Catheter to Treat Subjects Who Have Coronary Artery Disease (CAD) Involving In-Stent Restenosis (ISR) or an Unstented Lesion in a Small Coronary Vessel (DNSV).
Enrollment
60 pts
Location
Uzbekistan
Sponsor
Tonic Medical, Inc.
View Trial →
NCT07662317
Recruiting
Construction of a Prospective Cohort Database for the Perioperative Period of Cardiac Surgery
Enrollment
10,000 pts
Location
China
Sponsor
Second Affiliated Hospital, Zh...
View Trial →
NCT06509893 Phase 4
Recruiting
Ticagrelore Alone Post PCI
Enrollment
5,400 pts
Location
Iran
Sponsor
Shiraz University of Medical S...
View Trial →
NCT06710210
Recruiting
Hybrid Percutaneous Coronary Intervention Combining a Bioresorbable Scaffold With Drug-coated Balloons Versus a Conventional Drug-eluting Stent-based Strategy in Patients With Long and Diffuse Coronary Artery Disease
Enrollment
150 pts
Location
Switzerland
Sponsor
University Hospital, Geneva
View Trial →
NCT05829889
Recruiting
Fractional Flow Reserve Versus Angiography for Treatment-Decision and Evaluation of Significant Left MAIN Coronary Artery Disease
Enrollment
960 pts
Location
Hong Kong, India, Ja...
Sponsor
Seung-Jung Park
View Trial →
NCT03217006
Recruiting
Randomization of Single vs Multiple Arterial Grafts
Enrollment
4,300 pts
Location
United States, Austr...
Sponsor
Weill Medical College of Corne...
View Trial →
NCT07766434
Recruiting
A Prospective Multicenter Real-World Registry of Quantitative Flow Ratio-Guided Coronary REvascularization and QuAlity evaLuation
Enrollment
10,000 pts
Location
China
Sponsor
China National Center for Card...
View Trial →
NCT06228456 Phase 4
Recruiting
Effects of Low-dose Ticagrelor vs. Clopidogrel in Stable Patients Undergoing Elective Percutaneous Coronary Intervention
Enrollment
50 pts
Location
United States
Sponsor
University of Florida
View Trial →
NCT06793774
Recruiting
Risk Evaluation by COronary Imaging and Artificial intelliGence Based fuNctIonal analyZing tEchniques - III
Enrollment
300 pts
Location
China
Sponsor
Ruijin Hospital
View Trial →
NCT05923489
Recruiting
Routine Angiography Follow-Up After Percutaneous Coronary Intervention in High-Risk Patients
Enrollment
2,618 pts
Location
China
Sponsor
Second Affiliated Hospital, Zh...
View Trial →
NCT05230446
Recruiting
PRospective Evaluation of Complete Revascularization in Patients With multiveSsel Disease Excluding chroNic Total Occlusions
Enrollment
609 pts
Location
Netherlands
Sponsor
Erasmus Medical Center
View Trial →
NCT07883499
Recruiting
Prospective Study Protocol for Multiparametric PCCT Assessment of Early Ventricular Outcomes After CABG
Enrollment
150 pts
Location
China
Sponsor
Xin Lou
View Trial →
NCT02038127
Recruiting
Gangwon PCI Prospective Registry
Enrollment
10,000 pts
Location
South Korea
Sponsor
Yonsei University
View Trial →
NCT05380622
Recruiting
CHART Study of Coronary CT Angiography in Coronary Artery Disease
Enrollment
5,000 pts
Location
China
Sponsor
Shanghai Zhongshan Hospital
View Trial →
NCT06512493
Recruiting
South East (Zuid Oost) Netherlands Heart Registry
Enrollment
99,999 pts
Location
Netherlands
Sponsor
Radboud University Medical Cen...
View Trial →
NCT07276282 Phase 3
Recruiting
Effects of Ziltivekimab on Coronary Atherosclerotic Burden in Patients With Acute Myocardial Infarction
Enrollment
332 pts
Location
Switzerland
Sponsor
ECRI bv
View Trial →
NCT04808401
Recruiting
Influence of Oxygen on Perioperative Outcome in Patients Undergoing General Anaesthesia for Elective Non-cardiac Surgery
Enrollment
110 pts
Location
Switzerland
Sponsor
Insel Gruppe AG, University Ho...
View Trial →
NCT05437965
Recruiting
National Multicenter Cohort Registry Study of Rapid rEcurrences of Coronary Unexplained In-stent Restenosis
Enrollment
1,000 pts
Location
China
Sponsor
China National Center for Card...
View Trial →
NCT04939207
Recruiting
Safety and Cost-efficiëncy of New Imaging Techniques in Patients Suspected of Coronary Artery Disease
Enrollment
825 pts
Location
Netherlands
Sponsor
St. Antonius Hospital
View Trial →
NCT06541691
Recruiting
Coated or Chewable Aspirin and a Hybrid Strategy to Mitigate Adverse Effects of Air Pollution in Stable Atherosclerotic Disease
Enrollment
3,000 pts
Location
Iran
Sponsor
Rajaie Cardiovascular Medical ...
View Trial →
NCT05111288
Recruiting
Influence of Pulse Electromagnetic Field Therapy on Myocardial Ischemia
Enrollment
120 pts
Location
United States
Sponsor
Mayo Clinic
View Trial →
NCT06821191 Phase 4
Recruiting
Comparison of Dual Antiplatelet Therapy De-escalation by Dose Reduction Versus Switching in Patients Undergoing PCI: The Switching Antiplatelet-8 (SWAP-8) Study
Enrollment
78 pts
Location
United States
Sponsor
University of Florida
View Trial →
NCT05845489 Phase 4
Recruiting
Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis- CloPidogREl for Primary preVENTION (HOST-PREVENTION)
Enrollment
11,086 pts
Location
South Korea
Sponsor
Seoul National University Hosp...
View Trial →
NCT06459934
Recruiting
Clinical Outcomes of Cardiovascular Disease
Enrollment
30,000 pts
Location
China
Sponsor
Xinjiang Medical University
View Trial →
NCT06559332
Recruiting
Coronary Artery Disease Assessment Strategies in TAVI Patients
Enrollment
546 pts
Location
Switzerland
Sponsor
Insel Gruppe AG, University Ho...
View Trial →
NCT05427084 Phase 2, Phase 3
Recruiting
Canagliflozin Targeting Vascular Inflammation
Enrollment
24 pts
Location
Canada
Sponsor
Ottawa Heart Institute Researc...
View Trial →
NCT07559903
Recruiting
ANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)
Enrollment
5,000 pts
Location
United States, Germa...
Sponsor
Emory University
View Trial →
NCT06399692 Phase 3
Recruiting
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Women
Enrollment
600 pts
Location
United States
Sponsor
Weill Medical College of Corne...
View Trial →
NCT06814587
Recruiting
Hyperpolarized 13C Pyruvate-MRI and FDG-PET in a Single Exam for the Prognosis of Ischemic Cardiomyopathy
Enrollment
15 pts
Location
United States
Sponsor
University of Texas Southweste...
View Trial →
NCT06551662
Recruiting
DCB vs. DES in Bifurcation Coronary Lesions
Enrollment
321 pts
Location
Italy, Poland, Roman...
Sponsor
Fondazione Ricerca e Innovazio...
View Trial →
NCT07613996
Recruiting
Impact of Hyperemic State on Angio-IMR Performance
Enrollment
192 pts
Location
China
Sponsor
Shanghai Zhongshan Hospital
View Trial →
NCT05292651
Recruiting
Optimal Stent Deployment Strategy of Contemporary Stents
Enrollment
248 pts
Location
Netherlands
Sponsor
Albert Schweitzer Hospital
View Trial →
NCT05618353 Phase 4
Recruiting
The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial
Enrollment
700 pts
Location
United States
Sponsor
VA Office of Research and Deve...
View Trial →
NCT07917234
Recruiting
Computational μFR-Guided Versus Angiographic Guidance in Drug-Coated Balloon Angioplasty
Enrollment
250 pts
Location
Italy
Sponsor
Centro Cardiologico Monzino
View Trial →
NCT07795645
Recruiting
Validating a Medical AI Fine-Tuning Platform for Major Diseases
Enrollment
96,000 pts
Location
China
Sponsor
Beijing Friendship Hospital
View Trial →
NCT06779630
Recruiting
Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions
Enrollment
150 pts
Location
United States, Austr...
Sponsor
Teleflex
View Trial →
NCT07773064
Recruiting
Identification for High Risk of Coronary Heart Disease Based on Quantitative Analysis of Fundus Vessels and Metabolic Molecules
Enrollment
3,000 pts
Location
China
Sponsor
Beijing Hospital
View Trial →
NCT06567795
Recruiting
PRimary IndividualiZed Evaluation of Cardiovascular Events in Patients With Diabetes Mellitus Using hemoTAG
Enrollment
189 pts
Location
United States
Sponsor
Aventusoft, LLC.
View Trial →
NCT07034157
Recruiting
A Real-World Study on Ultrasound-Based Screening and Integrated Therapeutic Strategies for Patients With Concomitant Coronary and Cervicocephalic Artery Stenosis
Enrollment
1,000 pts
Location
China
Sponsor
Beijing Anzhen Hospital
View Trial →
NCT07324720
Recruiting
Strategic Comparison Of Ischemia-based Versus Plaque Burden and vulnErability-based Revascularization in High-Risk Coronary Artery Disease Patients
Enrollment
1,944 pts
Location
South Korea
Sponsor
Bon-Kwon Koo
View Trial →
NCT06878729
Recruiting
Antegrade Dissection and Re-entry Versus Retrograde Strategy in CTO PCI
Enrollment
74 pts
Location
Poland
Sponsor
National Institute of Cardiolo...
View Trial →
NCT05635227
Recruiting
Dexamethasone, Olanzapine, Hemodynamics, and Ventilation in Cardiac Surgery
Enrollment
1,200 pts
Location
Denmark
Sponsor
Copenhagen University Hospital...
View Trial →
NCT02792075
Recruiting
Prognosis of Coronary Stenosis Based on Intracoronary Imaging; A Multicenter, Prospective Observational Study
Enrollment
4,000 pts
Location
South Korea
Sponsor
Seung-Jung Park
View Trial →
NCT05860400
Recruiting
Efficacy and Safety of Comprehensive Treatment in Patients With IR-CAD: a Self-controlled Cohort Study
Enrollment
39 pts
Location
China
Sponsor
Peking Union Medical College H...
View Trial →

Related Conditions

heart failure (3) percutaneous coronary intervention (3) coronary artery disease left main (2) stable angina (2) coronary artery disease progression (2) coronary artery stenosis (2) coronary artery restenosis (2) inflammation (2) inflammatory disease (2) inflammation vascular (2) chronic coronary syndrome (2) in stent stenosis restenosis of coronary artery stent (2)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology