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Medical Condition

coronary artery disease

Total Trials

47

Recruiting Now

47

Trial Phases

Phase 4, Phase 2

ClinicalMetric tracks all active clinical trials for coronary artery disease sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — coronary artery disease Clinical Trials

How many clinical trials are currently recruiting for coronary artery disease?

ClinicalMetric currently tracks 47 actively recruiting clinical trials for coronary artery disease, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 47. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for coronary artery disease?

coronary artery disease research spans Phase 2 (1 trial), Phase 4 (5 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a coronary artery disease clinical trial?

Eligibility criteria for coronary artery disease trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 2

1

Phase 4

5

Top Sponsors

China National Center for Cardiovascular Diseases 4 trials

Yonsei University 2 trials

Seung-Jung Park 2 trials

Pauls Stradins Clinical University Hospital 2 trials

Peking Union Medical College Hospital 1 trial

Recruiting Clinical Trials

Disease Characteristics of IR-CAD: a Case-control Study

Peking Union Medical College H...

Preliminary Exploration of Factors Affecting Complete Hemostasis and Supine Time After Removal of Femoral Arterial Sheath in ICU Patients

National Taiwan University Hos...

Surgical Versus Percutaneous Revascularization in Patients With Reduced Left Ventricular Function (STICH 3.0-NL)

University Medical Center Gron...

Product Surveillance Registry

United States, Argen...

Comparison of Vessel-FFR Versus FFR in Intermediate Coronary Stenoses

Helios Health Institute GmbH

NCT05638867 Phase 4

NOAC Therapy Guided by PARIS Risk Score and D-dimer in Patients With ACS After PCI

China National Center for Card...

Stents Versus PAclitaxel Coated Balloons for Revascularization of CompleX and Small Coronary Vessels (SPARX) Trial

Translumina GmbH

Implementing Individualized Patient Reported Outcome Measures in Routine Care of Patients With Coronary Artery Disease

University of Calgary

A Danish ICD-study in Patients with Coronary Artery Disease Resuscitated from Ventricular Fibrillation

Rigshospitalet, Denmark

Drug-coated Balloon Treatment

Turkey (Türkiye)

Istanbul Mehmet Akif Ersoy Edu...

Smart Angioplasty Research Team-Coronary CT Angiography Versus Standard Care as Follow-up Strategies in High-Risk Patients After PCI (SMART-CARE)

Samsung Medical Center

Survival and cArdiovascular eVents in Patients With Acute Myocardial Infarction

Peking University First Hospit...

Expanded Studies on the SCAPIS Stockholm Reexamination Cohort

Danderyd Hospital

CCTA-Based vs CAG-Based CABG: A Multicenter Pragmatic Non-Inferiority Trial

Ruijin Hospital

Intravascular Ultrasound-Guided PCI in Patients With Chronic Kidney Disease

First Affiliated Hospital Xi'a...

QFR-Guided Virtual Stenting for Preprocedural Physiological Optimization of Percutaneous Coronary Intervention: A Randomized Controlled Trial

China National Center for Card...

National Multicenter Cohort Registry Study of Rapid rEcurrences of Coronary Unexplained In-stent Restenosis

China National Center for Card...

IVUS Guided PCI in Patients With Chronic Kidney Disease

Assistance Publique - Hôpitaux...

NCT06606821 Phase 4

The Effects of Tirzepatide in People With Overweight/Obesity and Coronary Artery Disease

NCT05618353 Phase 4

The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial

VA Office of Research and Deve...

NCT06917664 Phase 4

Treatment of Moderate Ischemic Mitral Regurgitation in Patients With Coronary Artery Disease

China National Center for Card...

Ultrathin Strut Sirolimus-eluting Stent With Bioabsorbable Polymer in Patients Receiving Chronic Oral Anticoagulation

Fundación EPIC

Decision Support Tool for Revascularisation Options in Coronary Artery Disease

University of Leicester

Coated or Chewable Aspirin and a Hybrid Strategy to Mitigate Adverse Effects of Air Pollution in Stable Atherosclerotic Disease

Rajaie Cardiovascular Medical ...

CABG or PCI in Patients With Ischemic Cardiomyopathy

Vastra Gotaland Region

NCT05845489 Phase 4

Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis- CloPidogREl for Primary preVENTION (HOST-PREVENTION)

Seoul National University Hosp...

Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence

University of Tennessee

µQFR for Branch Stenosis After Single Stent in Bifurcation Lesions

Shanghai Zhongshan Hospital

The COMPLETE Treatment of Bifurcation With Two-stent Techniques: Randomized Comparison of Crush Versus Culotte Technique

Yonsei University

Observational Study for Left Main Disease Treatment

China, Malaysia, Sou...

Seung-Jung Park

HEMOSTATİC PAD AND SANDBAG

Turkey (Türkiye)

Uludag University

Video-based Intervention to Reduce Anxiety in Patients Undergoing Elective PCI

Tan Tock Seng Hospital

Selective Coronary Revascularization in Peripheral Artery Disease Patients (SCOREPAD Trial)

Pauls Stradins Clinical Univer...

Gangwon PCI Prospective Registry

Yonsei University

Resting Full-cycle Flow Ratio (RFR) Versus Angiography to Guide Revascularization Strategy in Patients Undergoing Coronary Artery By-pass Grafting (CABG)

Belgium, Poland, Slo...

Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronary Artery Disease: Validation by Quantitative Cardiac MRI Perfusion

The University of Hong Kong

Percutaneous Coronary Intervention Registry FRIBOURG

University of Freiburg

Biochemical and Electrocardiographic Signatures in the Detection of Exercise-induced Myocardial Ischemia

University Hospital, Basel, Sw...

Study on the Preferences for PCI Implantation Devices Among Doctors and Patients

Xijing Hospital

Latvian Early Atherosclerosis Registry

Pauls Stradins Clinical Univer...

Coronary Computed Tomography Angiography (CCTA) for the Pre-procedural Planning of Percutaneous Coronary Intervention

Minneapolis Heart Institute Fo...

COMPLEX Registry - a Prospective COhort Study to Describe the Management and Outcomes of Patients Presenting with CompLEX and Calcified Coronary Artery Disease

Luzerner Kantonsspital

The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)

United States, Austr...

Sunnybrook Health Sciences Cen...

CRIC Combined With MFT for Cardiovascular Adverse Events in Patients With Incomplete Revascularization of CAD

Henan Institute of Cardiovascu...

MAIN-IMAGE Registry

Goethe University

NCT07118930 Phase 2

Study of Sivelestat Sodium in OPCABG

Affiliated Hospital of Nantong...

Study of the Natural History of FFR Guided Percutaneous Coronary Intervention

Seung-Jung Park

Related Conditions

percutaneous coronary intervention (4) ischemic heart disease (4) heart failure (2) acute myocardial infarction (2) chronic kidney diseases (2) peripheral arterial disease (2) angina stable (2) coronary artery stenosis (1) coronary artery restenosis (1) coronary artery disease progression (1) inflammation (1) inflammatory disease (1)

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology