State MO
Clinical Trials in Missouri
Missouri is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Missouri and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 275 actively recruiting studies with Missouri sites out of 275 registered in total. The busiest research areas in Missouri are Obesity, Heart Failure, Multiple Myeloma. Leading sponsors running trials in the state include Washington University School of Medicine, National Cancer Institute (NCI), AstraZeneca. By stage, Missouri trials break down as Phase 1 (52), Phase 2 (71), Phase 3 (78), Phase 4 (10).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Missouri
Frequently Asked Questions — Clinical Trials in Missouri
How many clinical trials are currently recruiting in Missouri?
ClinicalMetric currently tracks 275 actively recruiting clinical trials with at least one location in Missouri. The total number of registered studies—including active but not currently enrolling trials—is 275. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Missouri?
Missouri hosts clinical trials across a broad range of medical conditions, including Obesity, Heart Failure, Multiple Myeloma, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Missouri serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Missouri?
To join a clinical trial in Missouri, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Missouri maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Missouri
NCT05796375 Phase 2
Recruiting
Replacing Invasive Cystoscopy With Urine Testing for Non-muscle Invasive Bladder...
Condition
Non-muscle-invasive Bladder Cancer
Enrollment
240 pts
Location
United States
Sponsor
White River Junction Veterans
NCT07221357 Phase 2, Phase 3
Recruiting
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Che...
Condition
Untreated, Unresectable, or Metastatic Colorectal Cancer
Enrollment
990 pts
Location
United States, Argentina, Australia
Sponsor
Bristol-Myers Squibb
NCT04640584 N/A
Recruiting
C-Brace Prospective Registry
Condition
Pareses
Enrollment
250 pts
Location
United States, Australia, Germany
Sponsor
Otto Bock Healthcare Products
NCT04065399 Phase 1, Phase 2
Recruiting
A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rea...
Condition
Acute Myeloid Leukemia
Enrollment
447 pts
Location
United States, Australia, Canada
Sponsor
Syndax Pharmaceuticals
NCT05552222 Phase 3
Recruiting
A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR)...
Condition
Multiple Myeloma
Enrollment
1,590 pts
Location
United States, Australia, Austria
Sponsor
Janssen Research & Development
NCT07231419 Phase 3
Recruiting
Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With ...
Condition
Diabetic Peripheral Neuropathic Pain
Enrollment
734 pts
Location
United States
Sponsor
Vertex Pharmaceuticals Incorpo
NCT05919264 Phase 1, Phase 2
Recruiting
FOG-001 in Locally Advanced or Metastatic Solid Tumors
Condition
Cancer
Enrollment
619 pts
Location
United States, Australia
Sponsor
Parabilis Medicines, Inc.
NCT04629014 N/A
Recruiting
Prospective Multisite Study of Quality of Life in Pediatric Intestinal Failure
Condition
Pediatric Intestinal Failure
Enrollment
750 pts
Location
United States, Canada
Sponsor
Boston Children's Hospital
NCT02744677 N/A
Recruiting
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients...
Condition
Complex Congenital Heart Defect
Enrollment
108 pts
Location
United States
Sponsor
Edwards Lifesciences
NCT04047628 Phase 3
Recruiting
Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for ...
Condition
Relapsing Multiple Sclerosis
Enrollment
156 pts
Location
United States
Sponsor
National Institute of Allergy
NCT06307665 Phase 3
Recruiting
Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As ...
Condition
Asthma
Enrollment
440 pts
Location
United States, China, Mexico
Sponsor
AstraZeneca
NCT06657222 Phase 1, Phase 2
Recruiting
First in Human Study of TUB-030 in Patients With Advanced Solid Tumors
Condition
Advanced Solid Tumors
Enrollment
250 pts
Location
United States, Canada, France
Sponsor
Gilead Sciences
NCT06127199 N/A
Recruiting
Contraceptive Efficacy Study of Ovaprene
Condition
Contraception
Enrollment
656 pts
Location
United States
Sponsor
Daré Bioscience, Inc.
NCT07091500 N/A
Recruiting
Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Therapy and Exercise Training i...
Condition
Obesity
Enrollment
40 pts
Location
United States
Sponsor
Washington University School o
NCT07781800 N/A
Recruiting
Navigation Interventions for Patients With Breast Cancer and High-risk Social De...
Condition
Breast Cancer
Enrollment
180 pts
Location
United States
Sponsor
Washington University School o
NCT05564377 Phase 2
Recruiting
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally A...
Condition
Advanced Malignant Solid Neoplasm
Enrollment
2,900 pts
Location
United States, Puerto Rico
Sponsor
National Cancer Institute (NCI
NCT06121011 N/A
Recruiting
A Global Prospective Observational Registry of Patients With Pompe Disease
Condition
Pompe Disease
Enrollment
500 pts
Location
United States, Austria, Belgium
Sponsor
Amicus Therapeutics
NCT06848309 N/A
Recruiting
Dissecting Human Immune Responses to Infection With Influenza or SARS-CoV-2
Condition
Influenza
Enrollment
300 pts
Location
United States
Sponsor
Washington University School o
NCT06241456 Phase 1
Recruiting
FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibod...
Condition
Advanced Solid Tumor
Enrollment
351 pts
Location
United States
Sponsor
Fate Therapeutics
NCT06087029 N/A
Recruiting
IMPRoving Outcomes in Vascular DisEase - Aortic Dissection
Condition
Type B Aortic Dissection
Enrollment
1,100 pts
Location
United States, Canada
Sponsor
Duke University
NCT07266831 Phase 2, Phase 3
Recruiting
A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have No...
Condition
Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Enrollment
570 pts
Location
United States, Argentina, Canada
Sponsor
Merck Sharp & Dohme LLC
NCT05446272 N/A
Recruiting
The Diaphragmatic Initiated Ventilatory Assist (DIVA) Trial
Condition
Extubation Failure
Enrollment
478 pts
Location
United States, Canada
Sponsor
University of Pennsylvania
NCT05654922 Phase 3
Recruiting
Study to Evaluate ARINA-1 in the Prevention of Bronchiolitis Obliterans Progress...
Condition
Pre-Bronchiolitis Obliterans Syndrome
Enrollment
100 pts
Location
United States
Sponsor
Renovion, Inc.
NCT07563270 N/A
Recruiting
GAPcareAD: A Brief Emergency Department Intervention to Address Post-Fall Care N...
Condition
Alzheimer's Disease and Related Dementia
Enrollment
700 pts
Location
United States
Sponsor
University of Colorado, Denver
NCT07082803 Phase 1
Recruiting
TLN-121 in Relapsed or Refractory Non-Hodgkin Lymphomas
Condition
Lymphoma
Enrollment
180 pts
Location
United States, Australia, Canada
Sponsor
Treeline Biosciences, Inc.
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology