State MO
Clinical Trials in Missouri
Missouri is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Missouri and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 270 actively recruiting studies with Missouri sites out of 270 registered in total. The busiest research areas in Missouri are Breast Cancer, Prostate Cancer, Multiple Myeloma. Leading sponsors running trials in the state include Washington University School of Medicine, National Cancer Institute (NCI), University of Missouri-Columbia. By stage, Missouri trials break down as Phase 1 (53), Phase 2 (82), Phase 3 (85), Phase 4 (10).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Missouri
Frequently Asked Questions — Clinical Trials in Missouri
How many clinical trials are currently recruiting in Missouri?
ClinicalMetric currently tracks 270 actively recruiting clinical trials with at least one location in Missouri. The total number of registered studies—including active but not currently enrolling trials—is 270. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Missouri?
Missouri hosts clinical trials across a broad range of medical conditions, including Breast Cancer, Prostate Cancer, Multiple Myeloma, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Missouri serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Missouri?
To join a clinical trial in Missouri, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Missouri maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Missouri
NCT06898333 N/A
Recruiting
Implementation and Effectiveness of the BJC-Pink and Pearl Project on Lung Cance...
Condition
Lung Cancer
Enrollment
279 pts
Location
United States
Sponsor
Washington University School o
NCT07361510 Phase 3
Recruiting
A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participan...
Condition
Non-Small Cell Lung Cancer (NSCLC)
Enrollment
750 pts
Location
United States, Argentina, Australia
Sponsor
Bristol-Myers Squibb
NCT06773910 Phase 2
Recruiting
BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lu...
Condition
Limited Stage Small Cell Lung Cancer
Enrollment
250 pts
Location
United States
Sponsor
SCRI Development Innovations,
NCT07201558 Phase 1
Recruiting
Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE P...
Condition
Rheumatoid Arthritis
Enrollment
48 pts
Location
United States, Australia, Belgium
Sponsor
AstraZeneca
NCT07379684 Phase 1
Recruiting
A Study of Amicidin-β Topical Solution for Patients With Surgical or Traumatic W...
Condition
Surgical Wound Infection
Enrollment
44 pts
Location
United States
Sponsor
Macro Biologics, Inc.
NCT02994433 Phase 1
Recruiting
NMDA Receptor Antagonist Nitrous Oxide Targets Affective Brain Circuits
Condition
Depressive Disorder, Major
Enrollment
60 pts
Location
United States
Sponsor
Washington University School o
NCT07569926 Phase 4
Recruiting
Impact of Fluciclovine (18F) PET (Positron Emission Tomography) on the Managemen...
Condition
Prostate Cancer
Enrollment
142 pts
Location
United States
Sponsor
Blue Earth Diagnostics
NCT06617325 Phase 3
Recruiting
A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Part...
Condition
Systemic Lupus Erythematosus
Enrollment
450 pts
Location
United States, Argentina, Belgium
Sponsor
UCB Biopharma SRL
NCT06979362 Phase 2
Recruiting
A Research Study Comparing Different Doses of CDR132L With Placebo on the Struct...
Condition
Heart Failure
Enrollment
200 pts
Location
United States, Canada, Germany
Sponsor
Novo Nordisk A/S
NCT07052903 Phase 3
Recruiting
TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloid...
Condition
Transthyretin Amyloidosis With Cardiomyopathy
Enrollment
1,750 pts
Location
United States, Argentina, Australia
Sponsor
Alnylam Pharmaceuticals
NCT07200102 Phase 1
Recruiting
Selinexor Maintenance Post CAR-T Cell Therapy for Multiple Myeloma
Condition
Multiple Myeloma
Enrollment
20 pts
Location
United States
Sponsor
Washington University School o
NCT06527157 N/A
Recruiting
Investigations of Reproductive Cancers in Women
Condition
Uterine Cancer
Enrollment
4,500 pts
Location
United States
Sponsor
PinkDx, Inc.
NCT06241456 Phase 1
Recruiting
FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibod...
Condition
Advanced Solid Tumor
Enrollment
351 pts
Location
United States
Sponsor
Fate Therapeutics
NCT06072781 Phase 3
Recruiting
A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade ...
Condition
Low Grade Serous Ovarian Cancer
Enrollment
270 pts
Location
United States, Australia, Belgium
Sponsor
Verastem, Inc.
NCT06906341 Phase 2
Recruiting
Relacorilant in Combination With Different Treatment Regimens in Patients With G...
Condition
Ovarian Cancer
Enrollment
270 pts
Location
United States, Belgium, France
Sponsor
Corcept Therapeutics
NCT07074288 N/A
Recruiting
Obstructive Sleep Apnea Non-PAP Outcomes and Viable Alternatives
Condition
Obstructive Sleep Apnea
Enrollment
60 pts
Location
United States
Sponsor
Washington University School o
NCT06127407 Phase 3
Recruiting
Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chon...
Condition
Locally Advanced or Metastatic Conventional Chondrosarcoma With an IDH1 Mutation, Untreated or Previously Treated With 1 Systemic Treatment Regimen
Enrollment
136 pts
Location
United States, Australia, Belgium
Sponsor
Servier Bio-Innovation LLC
NCT07200830 Phase 3
Recruiting
Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA ...
Condition
Metastatic Castration-Resistant Prostate Carcinoma
Enrollment
1,524 pts
Location
United States
Sponsor
Alliance for Clinical Trials i
NCT03723928 N/A
Recruiting
S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Re...
Condition
Anatomic Stage IV Breast Cancer AJCC v8
Enrollment
739 pts
Location
United States, Guam, Puerto Rico
Sponsor
SWOG Cancer Research Network
NCT05856981 Phase 1
Recruiting
Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors
Condition
Solid Tumor, Adult
Enrollment
130 pts
Location
United States, Belgium, Spain
Sponsor
Sairopa B.V.
NCT03671044 Phase 3
Recruiting
A Study to Evaluate the Efficacy and Safety of Nanosomal Docetaxel Lipid Suspens...
Condition
Triple Negative Breast Cancer
Enrollment
657 pts
Location
United States, India
Sponsor
Jina Pharmaceuticals Inc.
NCT07160244 Phase 3
Recruiting
BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregn...
Condition
Healthy
Enrollment
6,000 pts
Location
United States, Argentina, Brazil
Sponsor
Pfizer
NCT04166409 Phase 3
Recruiting
A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients Wit...
Condition
Low Grade Astrocytoma
Enrollment
170 pts
Location
United States, Canada, Puerto Rico
Sponsor
National Cancer Institute (NCI
NCT07165028 Phase 3
Recruiting
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associ...
Condition
Metabolic Dysfunction-Associated Steatotic Liver Disease
Enrollment
4,500 pts
Location
United States, Argentina, Australia
Sponsor
Eli Lilly and Company
NCT05938465 Phase 1, Phase 2
Recruiting
Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in ...
Condition
Ileal Pouch
Enrollment
50 pts
Location
United States
Sponsor
Exegi Pharma, LLC
Page 1 of 11 — 270 trials total
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology