State KY
Clinical Trials in Kentucky
Kentucky is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Kentucky and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 140 actively recruiting studies with Kentucky sites out of 140 registered in total. The busiest research areas in Kentucky are Non-Small Cell Lung Cancer, Colorectal Cancer, Ulcerative Colitis. Leading sponsors running trials in the state include University of Louisville, National Cancer Institute (NCI), Merck Sharp & Dohme LLC. By stage, Kentucky trials break down as Phase 1 (20), Phase 2 (36), Phase 3 (42), Phase 4 (5).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Kentucky
Frequently Asked Questions — Clinical Trials in Kentucky
How many clinical trials are currently recruiting in Kentucky?
ClinicalMetric currently tracks 140 actively recruiting clinical trials with at least one location in Kentucky. The total number of registered studies—including active but not currently enrolling trials—is 140. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Kentucky?
Kentucky hosts clinical trials across a broad range of medical conditions, including Non-Small Cell Lung Cancer, Colorectal Cancer, Ulcerative Colitis, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Kentucky serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Kentucky?
To join a clinical trial in Kentucky, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Kentucky maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Kentucky
NCT07589608 Phase 2
Recruiting
A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone...
Condition
Overweight
Enrollment
400 pts
Location
United States
Sponsor
Eli Lilly and Company
NCT06708897 Phase 1
Recruiting
A Study of Lonitoclax (ZE50-0134) in Relapsed or Refractory B-cell Malignancies
Condition
CLL / SLL
Enrollment
84 pts
Location
United States
Sponsor
Lomond Therapeutics Holdings,
NCT05066217 Phase 3
Recruiting
An Efficacy and Safety Study of Clemizole HCl in Patients With Lennox-Gastaut Sy...
Condition
Lennox Gastaut Syndrome
Enrollment
260 pts
Location
United States, China, Hungary
Sponsor
Epygenix
NCT07437950 Phase 2
Recruiting
Comparing Different Treatment Lengths for Venetoclax in Older People With Newly ...
Condition
Acute Myeloid Leukemia
Enrollment
126 pts
Location
United States, Puerto Rico
Sponsor
National Cancer Institute (NCI
NCT07018323 Phase 2
Recruiting
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatme...
Condition
Graves' Disease
Enrollment
210 pts
Location
United States, Australia, Brazil
Sponsor
Immunovant Sciences GmbH
NCT05178069 Phase 2
Recruiting
LGG Supplementation in Patients With AUD and ALD
Condition
Alcohol Use Disorder
Enrollment
60 pts
Location
United States
Sponsor
University of Louisville
NCT06422806 Phase 3
Recruiting
Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone f...
Condition
Metastatic Dedifferentiated Liposarcoma
Enrollment
365 pts
Location
United States, Canada, Puerto Rico
Sponsor
National Cancer Institute (NCI
NCT06401421 N/A
Recruiting
EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Brea...
Condition
Breast Cancer
Enrollment
1,800 pts
Location
United States, Canada
Sponsor
Exact Sciences Corporation
NCT07169734 Phase 1, Phase 2
Recruiting
A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Ad...
Condition
Cervical Squamous Cell Carcinoma
Enrollment
180 pts
Location
United States, France, Hong Kong
Sponsor
Alentis Therapeutics AG
NCT06424288 Phase 3
Recruiting
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps Peop...
Condition
Heart Failure
Enrollment
6,712 pts
Location
United States, Argentina, Australia
Sponsor
Boehringer Ingelheim
NCT06256588 Phase 3
Recruiting
A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants Wit...
Condition
Neoplasms, Head and Neck
Enrollment
864 pts
Location
United States, Argentina, Australia
Sponsor
GlaxoSmithKline
NCT07682896 Phase 2
Recruiting
Evaluation of YB-101 for Safety, Tolerability, Pharmacokinetics, and Efficacy in...
Condition
Graves' Disease
Enrollment
232 pts
Location
United States, Australia
Sponsor
Yarrow Bioscience, Inc.
NCT06276452 N/A
Recruiting
Supporting Resilience Among Re-entered Seniors
Condition
Chronic Disease
Enrollment
8 pts
Location
United States
Sponsor
University of Louisville
NCT06399692 Phase 3
Recruiting
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARG...
Condition
Coronary Artery Disease
Enrollment
600 pts
Location
United States
Sponsor
Weill Medical College of Corne
NCT07028749 Phase 2
Recruiting
Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol
Condition
Hypertriglyceridemia
Enrollment
316 pts
Location
United States, Australia, Canada
Sponsor
Marea Therapeutics
NCT06207032 N/A
Recruiting
TEMPUS ARIES: A Biobank Registry Platform Study in Oncology
Condition
Cancer
Enrollment
500 pts
Location
United States, Puerto Rico
Sponsor
Tempus AI
NCT06019949 N/A
Recruiting
Spinal Cord Stimulation for Respiratory Rehabilitation in Patients With Chronic ...
Condition
Spinal Cord Injuries
Enrollment
36 pts
Location
United States
Sponsor
University of Louisville
NCT00736749 N/A
Recruiting
Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Gro...
Condition
Hematopoietic Cell Transplantation Recipient
Enrollment
25,000 pts
Location
United States, Puerto Rico
Sponsor
Children's Oncology Group
NCT06804642 N/A
Recruiting
Spinal Cord Stimulation for Parkinson's Disease Rehabilitation
Condition
Parkinson Disease
Enrollment
20 pts
Location
United States
Sponsor
University of Louisville
NCT06336122 N/A
Recruiting
OASIS: Peer Support for T2DM in Appalachia (Peer Participant)
Condition
Diabetes Mellitus, Type 2
Enrollment
76 pts
Location
United States
Sponsor
The University of Texas Medica
NCT07453888 Phase 3
Recruiting
Efficacy and Safety of Intranasal Cenegermin in Adult Participants With Non-Arte...
Condition
Non-Arteritic Anterior Ischemic Optic Neuropathy
Enrollment
272 pts
Location
United States, Australia, South Korea
Sponsor
Dompé Farmaceutici S.p.A
NCT05918861 Phase 3
Recruiting
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Rece...
Condition
Acute Coronary Syndrome
Enrollment
2,000 pts
Location
United States, Canada, Puerto Rico
Sponsor
DalCor Pharmaceuticals
NCT03072927 N/A
Recruiting
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
Condition
Lumbar Spinal Stenosis
Enrollment
8,000 pts
Location
United States
Sponsor
Stryker Instruments
NCT06710756 Phase 1, Phase 2
Recruiting
Lead-212 PSV359 Therapy for Patients With Solid Tumors
Condition
Pancreatic Ductal Adenocarcinoma
Enrollment
112 pts
Location
United States
Sponsor
Perspective Therapeutics
NCT04088071 N/A
Recruiting
Real-world Experience of Catheter Ablation for the Treatment of Arrhythmias
Condition
Paroxysmal Atrial Fibrillation
Enrollment
20,000 pts
Location
United States, Canada
Sponsor
Heart Rhythm Clinical and Rese
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology