State KY
Clinical Trials in Kentucky
Kentucky is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Kentucky and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 163 actively recruiting studies with Kentucky sites out of 163 registered in total. The busiest research areas in Kentucky are Colorectal Cancer, Ovarian Cancer, Hypertension. Leading sponsors running trials in the state include National Cancer Institute (NCI), University of Louisville, SWOG Cancer Research Network. By stage, Kentucky trials break down as Phase 1 (21), Phase 2 (49), Phase 3 (59), Phase 4 (8).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Kentucky
Frequently Asked Questions — Clinical Trials in Kentucky
How many clinical trials are currently recruiting in Kentucky?
ClinicalMetric currently tracks 163 actively recruiting clinical trials with at least one location in Kentucky. The total number of registered studies—including active but not currently enrolling trials—is 163. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Kentucky?
Kentucky hosts clinical trials across a broad range of medical conditions, including Colorectal Cancer, Ovarian Cancer, Hypertension, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Kentucky serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Kentucky?
To join a clinical trial in Kentucky, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Kentucky maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Kentucky
NCT06318169 Phase 3
Recruiting
A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With ...
Condition
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis
Enrollment
1,350 pts
Location
United States, Argentina, Australia
Sponsor
89bio, Inc.
NCT05178056 N/A
Recruiting
Spinal Cord Stimulation and Respiration After Injury
Condition
Spinal Cord Injuries
Enrollment
30 pts
Location
United States
Sponsor
University of Louisville
NCT06841055 Phase 2
Recruiting
Safety and Preliminary Efficacy of Pumitamig (BNT327), an Investigational Therap...
Condition
Non-small Cell Lung Cancer
Enrollment
60 pts
Location
United States, Australia, South Korea
Sponsor
BioNTech SE
NCT06001827 N/A
Recruiting
SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study
Condition
Chronic Kidney Diseases
Enrollment
600 pts
Location
United States
Sponsor
VenoStent
NCT06917911 Phase 2
Recruiting
Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatm...
Condition
Core Binding Factor Acute Myeloid Leukemia
Enrollment
162 pts
Location
United States
Sponsor
National Cancer Institute (NCI
NCT05213676 Phase 4
Recruiting
De-implementing Inhaled Nitric Oxide for Congenital Diaphragmatic Hernia
Condition
Congenital Diaphragmatic Hernia
Enrollment
600 pts
Location
United States
Sponsor
The University of Texas Health
NCT06958328 Phase 3
Recruiting
Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer
Condition
Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma
Enrollment
356 pts
Location
United States, Canada
Sponsor
NRG Oncology
NCT07218809 Phase 3
Recruiting
AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy i...
Condition
Epithelial Ovarian Cancer
Enrollment
1,100 pts
Location
United States, Australia, Belgium
Sponsor
AstraZeneca
NCT05642611 Phase 3
Recruiting
Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemo...
Condition
Malignant Solid Neoplasm
Enrollment
777 pts
Location
United States
Sponsor
SWOG Cancer Research Network
NCT06830798 Phase 3
Recruiting
Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the ...
Condition
Delayed Graft Function
Enrollment
450 pts
Location
United States, Argentina, Australia
Sponsor
Alexion Pharmaceuticals, Inc.
NCT06246916 Phase 3
Recruiting
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Partic...
Condition
Melanoma
Enrollment
560 pts
Location
United States, Canada
Sponsor
Regeneron Pharmaceuticals
NCT04486833 Phase 1, Phase 2
Recruiting
Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lun...
Condition
Carcinoma, Non-Small Cell Lung
Enrollment
158 pts
Location
United States
Sponsor
Genprex, Inc.
NCT07061964 Phase 2
Recruiting
Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Rem...
Condition
Muscle Invasive Bladder Urothelial Carcinoma
Enrollment
111 pts
Location
United States
Sponsor
National Cancer Institute (NCI
NCT05183035 Phase 3
Recruiting
Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)
Condition
Acute Myeloid Leukemia
Enrollment
130 pts
Location
United States, Australia, Austria
Sponsor
PedAL BCU, LLC
NCT07523750 N/A
Recruiting
A Study of VARIPULSE Pulsed Field Ablation (PFA) Catheter and FARAWAVE PFA Cathe...
Condition
Atrial Fibrillation
Enrollment
566 pts
Location
United States
Sponsor
Biosense Webster, Inc.
NCT06500273 Phase 2
Recruiting
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
Condition
Large B-cell Lymphoma
Enrollment
250 pts
Location
United States, Australia, Canada
Sponsor
Allogene Therapeutics
NCT04743141 Phase 3
Recruiting
Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatme...
Condition
Acute Treatment of Migraine
Enrollment
600 pts
Location
United States, Poland, Spain
Sponsor
Pfizer
NCT04462770 Phase 3
Recruiting
A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrom...
Condition
Dravet Syndrome
Enrollment
150 pts
Location
United States, Argentina, Brazil
Sponsor
Epygenix
NCT07064473 Phase 3
Recruiting
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empag...
Condition
Diabetes Mellitus, Type 2
Enrollment
11,800 pts
Location
United States, Argentina, Australia
Sponsor
Boehringer Ingelheim
NCT06303505 Phase 1, Phase 2
Recruiting
FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Pa...
Condition
Ovarian Cancer
Enrollment
250 pts
Location
United States, Belgium, Germany
Sponsor
Tubulis GmbH
NCT00358943 N/A
Recruiting
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Preg...
Condition
Gaucher Disease
Enrollment
12,000 pts
Location
United States, Argentina, Australia
Sponsor
Genzyme, a Sanofi Company
NCT04476901 Phase 2
Recruiting
Administration of Allogeneic-MSC in Patients With Non-Ischemic Dilated Cardiomyo...
Condition
Non-ischemic Dilated Cardiomyopathy
Enrollment
136 pts
Location
United States
Sponsor
Joshua M Hare
NCT05658575 Phase 2, Phase 3
Recruiting
Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare
Condition
Acute Gout Flare
Enrollment
300 pts
Location
United States, France, Israel
Sponsor
Olatec Therapeutics, Inc.
NCT06274801 Phase 3
Recruiting
Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EX...
Condition
Pulmonary Arterial Hypertension
Enrollment
330 pts
Location
United States, Argentina, Australia
Sponsor
Gossamer Bio USA, Inc.
NCT05099003 Phase 1, Phase 2
Recruiting
A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diag...
Condition
Malignant Glioma
Enrollment
132 pts
Location
United States, Australia, Canada
Sponsor
National Cancer Institute (NCI
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology