State KY
Clinical Trials in Kentucky
Kentucky is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Kentucky and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 140 actively recruiting studies with Kentucky sites out of 140 registered in total. The busiest research areas in Kentucky are Non-Small Cell Lung Cancer, Colorectal Cancer, Ulcerative Colitis. Leading sponsors running trials in the state include University of Louisville, National Cancer Institute (NCI), Merck Sharp & Dohme LLC. By stage, Kentucky trials break down as Phase 1 (20), Phase 2 (36), Phase 3 (42), Phase 4 (5).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Kentucky
Frequently Asked Questions — Clinical Trials in Kentucky
How many clinical trials are currently recruiting in Kentucky?
ClinicalMetric currently tracks 140 actively recruiting clinical trials with at least one location in Kentucky. The total number of registered studies—including active but not currently enrolling trials—is 140. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Kentucky?
Kentucky hosts clinical trials across a broad range of medical conditions, including Non-Small Cell Lung Cancer, Colorectal Cancer, Ulcerative Colitis, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Kentucky serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Kentucky?
To join a clinical trial in Kentucky, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Kentucky maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Kentucky
NCT06005298 N/A
Recruiting
Alcohol Misuse, Gut Microbial Dysbiosis and PrEP Care Continuum: Application and...
Condition
Alcohol Use Disorder
Enrollment
120 pts
Location
United States
Sponsor
Shirish S Barve
NCT06524544 Phase 3
Recruiting
A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hzi...
Condition
Locally Advanced Urothelial Carcinoma
Enrollment
320 pts
Location
United States
Sponsor
National Cancer Institute (NCI
NCT07216339 N/A
Recruiting
Gamification Effects on the 6-Minute Walk Test in Children
Condition
Neuromuscular Diseases in Children
Enrollment
20 pts
Location
United States
Sponsor
David Toupin
NCT07213973 Phase 2
Recruiting
Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participant...
Condition
Hidradenitis Suppurativa (HS)
Enrollment
40 pts
Location
United States, Canada
Sponsor
Incyte Corporation
NCT04994756 N/A
Recruiting
Stroke Thrombectomy and Aneurysm Registry
Condition
Stroke
Enrollment
40,000 pts
Location
United States, Canada, Germany
Sponsor
Medical University of South Ca
NCT05172245 Phase 1
Recruiting
Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head...
Condition
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Enrollment
46 pts
Location
United States, Canada
Sponsor
National Cancer Institute (NCI
NCT03816345 Phase 1
Recruiting
Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Pa...
Condition
Autoimmune Disease
Enrollment
300 pts
Location
United States, Canada
Sponsor
National Cancer Institute (NCI
NCT04333537 Phase 2, Phase 3
Recruiting
Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Pat...
Condition
Buccal Mucosa Squamous Cell Carcinoma
Enrollment
686 pts
Location
United States, Canada
Sponsor
NRG Oncology
NCT06937086 Phase 3
Recruiting
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants W...
Condition
Ulcerative Colitis
Enrollment
350 pts
Location
United States, Austria, Belgium
Sponsor
Eli Lilly and Company
NCT06500273 Phase 2
Recruiting
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
Condition
Large B-cell Lymphoma
Enrollment
250 pts
Location
United States, Australia, Canada
Sponsor
Allogene Therapeutics
NCT06128629 Phase 3
Recruiting
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amylo...
Condition
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Enrollment
1,200 pts
Location
United States, Argentina, Australia
Sponsor
Intellia Therapeutics
NCT07003295 Phase 2
Recruiting
Testing the Anti-cancer Drug, Glofitamab, in Patients With Mantle Cell Lymphoma ...
Condition
Recurrent Mantle Cell Lymphoma
Enrollment
20 pts
Location
United States
Sponsor
National Cancer Institute (NCI
NCT04329728 Phase 1, Phase 2
Recruiting
The OPAL Study: AVM0703 for Treatment of Lymphoid Malignancies
Condition
Lymphoid Malignancies
Enrollment
144 pts
Location
United States
Sponsor
AVM Biotechnology Inc
NCT06486636 N/A
Recruiting
Pericardiotomy in Cardiac Surgery
Condition
Atrial Fibrillation
Enrollment
1,400 pts
Location
United States, Austria, Canada
Sponsor
Population Health Research Ins
NCT07564401 Phase 1, Phase 2
Recruiting
A Study to Evaluate DJI136, a DLL3-targeted CAR-T Therapy
Condition
Extensive-stage Small Cell Lung Cancer (ES-SCLC)
Enrollment
80 pts
Location
United States, Australia, Singapore
Sponsor
Novartis Pharmaceuticals
Page 6 of 6 — 140 trials total
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology