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Medical Condition
esophageal cancer
Total Trials
7
Recruiting Now
7
Trial Phases
Phase 1, Phase 2, Phase 2
Cancer clinical trials represent the largest single category of recruiting studies worldwide, encompassing everything from early-phase safety studies of novel oncology drugs to large Phase 3 comparisons against current standard-of-care chemotherapy regimens. The field has accelerated dramatically with the rise of immunotherapy, targeted therapies, and CAR-T cell treatments that have transformed outcomes for previously untreatable malignancies.
Trials include checkpoint inhibitors (PD-1/PD-L1 agents), KRAS inhibitors, ADC (antibody-drug conjugates), combination chemotherapy regimens, radiation protocols, and surgical technique comparisons. Many trials stratify by biomarker status (PD-L1 expression, TMB, MSI-H) to identify patients most likely to benefit.
The NCI, pharmaceutical sponsors, and academic cancer centers collectively fund thousands of oncology trials annually across every cancer type.
Frequently Asked Questions — esophageal cancer Clinical Trials
How many clinical trials are currently recruiting for esophageal cancer?
ClinicalMetric currently tracks 7 actively recruiting clinical trials for esophageal cancer, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 7. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for esophageal cancer?
esophageal cancer research spans Phase 1 (1 trial), Phase 2 (2 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a esophageal cancer clinical trial?
Eligibility criteria for esophageal cancer trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1 1
Phase 2 2
Top Sponsors
1 trial
1 trial
1 trial
1 trial
1 trial
Recruiting Clinical Trials
NCT06787313
Recruiting
Precision Palliative Care for Patients With Advanced Esophageal Cancer
Enrollment
624 pts
Location
China
Sponsor
Fudan University
NCT06790797
Recruiting
Investigating the Biomarkers in Tumor and Peripheral Blood to Evaluate the Efficacy of Cancer Immunotherapy in Chest Cancer Patients
Enrollment
50 pts
Location
China
Sponsor
Zhao Jun
NCT04675138
Recruiting
Development of a Clinical Decision Support System With Artificial Intelligence for Cancer Care
Enrollment
1,000 pts
Location
Germany, Japan, Sing...
Sponsor
National University Hospital, ...
NCT04734821
Recruiting
Fluorescence Image Guided Foregut Surgery
Enrollment
60 pts
Location
France
Sponsor
IHU Strasbourg
NCT06943521 Phase 1, Phase 2
Recruiting
A Study of MT-4561 in Patients With Various Advanced Solid Tumors
Enrollment
27 pts
Location
United States, Japan
Sponsor
Tanabe Pharma America, Inc.
NCT06403878 Phase 2
Recruiting
Safety and Efficacy of Neoadjuvant Immunochemotherapy in Elderly Patients With Resectable Esophageal Cancer
Enrollment
68 pts
Location
China
Sponsor
Sichuan University
NCT06419244
Recruiting
Myosteatosis in Oeso-gastric Cancer: Clinical Impacts
Enrollment
50 pts
Location
Belgium
Sponsor
Cliniques universitaires Saint...
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: April 2026 · Data Methodology