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Clinical Trials in Kentucky

Kentucky is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Kentucky and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.

Right now ClinicalMetric tracks 163 actively recruiting studies with Kentucky sites out of 163 registered in total. The busiest research areas in Kentucky are Colorectal Cancer, Ovarian Cancer, Hypertension. Leading sponsors running trials in the state include National Cancer Institute (NCI), University of Louisville, SWOG Cancer Research Network. By stage, Kentucky trials break down as Phase 1 (21), Phase 2 (49), Phase 3 (59), Phase 4 (8).

All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.

Total Trials
163
Recruiting Now
163
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Top Conditions in Kentucky
Colorectal Cancer (4)Ovarian Cancer (3)Hypertension (3)Obesity (3)Non-small Cell Lung Cancer (3)Stage III Pancreatic Cancer AJCC v8 (3)Spinal Cord Injuries (3)Acute Myeloid Leukemia (3)Heart Failure (2)Endometrial Cancer (2)NSCLC (2)Renal Insufficiency (2)

Frequently Asked Questions — Clinical Trials in Kentucky

How many clinical trials are currently recruiting in Kentucky?
ClinicalMetric currently tracks 163 actively recruiting clinical trials with at least one location in Kentucky. The total number of registered studies—including active but not currently enrolling trials—is 163. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Kentucky?
Kentucky hosts clinical trials across a broad range of medical conditions, including Colorectal Cancer, Ovarian Cancer, Hypertension, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Kentucky serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Kentucky?
To join a clinical trial in Kentucky, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Kentucky maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.

Recruiting Trials in Kentucky

NCT06129240 N/A
Recruiting
An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability ...
Condition
Pulmonary Hypertension
Enrollment
80 pts
Location
United States
Sponsor
Liquidia Technologies, Inc.
View Trial →
NCT04718168 N/A
Recruiting
GORE® ENFORM Biomaterial Product Study
Condition
Hernia, Ventral
Enrollment
245 pts
Location
United States
Sponsor
W.L.Gore & Associates
View Trial →
NCT06843317 Phase 1
Recruiting
Safety and Immunogenicity Study of Revaccination With SCB-1019T in Healthy Adult...
Condition
RSV Infection
Enrollment
160 pts
Location
United States
Sponsor
Clover Biopharmaceuticals USA,
View Trial →
NCT06616584 Phase 2, Phase 3
Recruiting
Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Adva...
Condition
Recurrent Lung Non-Small Cell Carcinoma
Enrollment
378 pts
Location
United States
Sponsor
SWOG Cancer Research Network
View Trial →
NCT05443126 Phase 1, Phase 2
Recruiting
A Study of EP0031 (Lunbotinib) in Patients With Advanced RET-altered Malignancie...
Condition
NSCLC
Enrollment
265 pts
Location
United States, France, Germany
Sponsor
Ellipses Pharma
View Trial →
NCT04071847 N/A
Recruiting
Abbott DBS Post-Market Study of Outcomes for Indications Over Time
Condition
Movement Disorders
Enrollment
1,000 pts
Location
United States, Australia, Finland
Sponsor
Abbott Medical Devices
View Trial →
NCT06672549 Phase 3
Recruiting
A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040...
Condition
Obesity
Enrollment
125 pts
Location
United States, Belgium, Brazil
Sponsor
Eli Lilly and Company
View Trial →
NCT06480760 Phase 1, Phase 2
Recruiting
Effects of Carnosine In Patients With Peripheral Arterial Disease Patients
Condition
Peripheral Arterial Disease
Enrollment
144 pts
Location
United States
Sponsor
Shahid Baba
View Trial →
NCT05677490 Phase 3
Recruiting
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanc...
Condition
Advanced Esophageal Adenocarcinoma
Enrollment
382 pts
Location
United States, Puerto Rico
Sponsor
Alliance for Clinical Trials i
View Trial →
NCT04270591 Phase 1, Phase 2
Recruiting
Assessment of Anti-tumor and Safety in Glumetinib in Patients With c-MET-positiv...
Condition
C-Met Exon 14 Mutation
Enrollment
183 pts
Location
United States, China, Japan
Sponsor
Haihe Biopharma Co., Ltd.
View Trial →
NCT06726161 Phase 1, Phase 2
Recruiting
Study of the Theranostic Pair RYZ811 (Diagnostic) and RYZ801 (Therapeutic) to Id...
Condition
Hepatocellular Carcinoma (HCC)
Enrollment
590 pts
Location
United States
Sponsor
RayzeBio, Inc.
View Trial →
NCT04202341 N/A
Recruiting
Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion...
Condition
Generalized Myasthenia Gravis
Enrollment
500 pts
Location
United States, Austria, Canada
Sponsor
Alexion Pharmaceuticals, Inc.
View Trial →
NCT07018869 Phase 3
Recruiting
Evaluating Whether an Educational Website Called Current Together After Cancer (...
Condition
Colorectal Cancer Stage II
Enrollment
1,057 pts
Location
United States, Guam, Puerto Rico
Sponsor
SWOG Cancer Research Network
View Trial →
NCT07060638 Phase 2
Recruiting
Integrated Therapies for Alcohol Use in Alcohol-associated Liver Disease (ITAALD...
Condition
Alcohol-associated Hepatitis
Enrollment
216 pts
Location
United States
Sponsor
Samer Gawrieh
View Trial →
NCT06019949 N/A
Recruiting
Spinal Cord Stimulation for Respiratory Rehabilitation in Patients With Chronic ...
Condition
Spinal Cord Injuries
Enrollment
36 pts
Location
United States
Sponsor
University of Louisville
View Trial →
NCT06382155 Phase 2
Recruiting
A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature
Condition
Idiopathic Short Stature
Enrollment
100 pts
Location
United States, Australia, France
Sponsor
BioMarin Pharmaceutical
View Trial →
NCT06317649 Phase 2
Recruiting
Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute M...
Condition
Acute Myeloid Leukemia
Enrollment
147 pts
Location
United States, Puerto Rico
Sponsor
National Cancer Institute (NCI
View Trial →
NCT06243211 N/A
Recruiting
Spinal Decompression Plus Nerve Graft Implantation Following TSCI
Condition
Spinal Cord Injuries
Enrollment
10 pts
Location
United States
Sponsor
Francis Farhadi
View Trial →
NCT07268638 Phase 2
Recruiting
A Study of Praliciguat in Participants With Focal Segmental Glomerulosclerosis (...
Condition
Focal Segmental Glomerulosclerosis
Enrollment
60 pts
Location
United States
Sponsor
Akebia Therapeutics
View Trial →
NCT05983432 Phase 1
Recruiting
Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lun...
Condition
Non Small Cell Lung Cancer
Enrollment
470 pts
Location
United States, France, Italy
Sponsor
SystImmune Inc.
View Trial →
NCT06237452 Phase 3
Recruiting
VE303 for Prevention of Recurrent Clostridioides Difficile Infection
Condition
Clostridium Difficile
Enrollment
852 pts
Location
United States, Australia, Belgium
Sponsor
Vedanta Biosciences, Inc.
View Trial →
NCT07225946 Phase 3
Recruiting
A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metas...
Condition
Prostatic Neoplasms, Castration-Resistant
Enrollment
800 pts
Location
United States, Australia, Belgium
Sponsor
Janssen Research & Development
View Trial →
NCT06264180 Phase 3
Recruiting
VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on A...
Condition
Advanced Melanoma
Enrollment
400 pts
Location
United States, France, Germany
Sponsor
Replimune, Inc.
View Trial →
NCT04678154 Phase 3
Recruiting
Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fr...
Condition
Post Operative Surgical Site Infection
Enrollment
600 pts
Location
United States
Sponsor
Major Extremity Trauma Researc
View Trial →
NCT05464251 N/A
Recruiting
Prospective Analysis of Spinal Epidural Abscess
Condition
Spinal Epidural Abscess
Enrollment
200 pts
Location
United States
Sponsor
Francis Farhadi
View Trial →
Page 4 of 7 — 163 trials total
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology