Medical Condition

opioid use

Total Trials

12

Recruiting Now

12

Trial Phases

Phase 3, Phase 2

ClinicalMetric tracks all active clinical trials for opioid use sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — opioid use Clinical Trials

How many clinical trials are currently recruiting for opioid use?

ClinicalMetric currently tracks 12 actively recruiting clinical trials for opioid use, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 12. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for opioid use?

opioid use research spans Phase 2 (1 trial), Phase 3 (2 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a opioid use clinical trial?

Eligibility criteria for opioid use trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 2

Phase 3

Top Sponsors

St. Louis University 1 trial

Endeavor Health 1 trial

Yale University 1 trial

Massachusetts General Hospital 1 trial

University of Aberdeen 1 trial

Recruiting Clinical Trials

NCT03823534 Phase 3

Recruiting

Post-Op Pain Control for Prophylactic Intramedullary Nailing.

Autonomic Neural Blockade in Bariatric Surgery

fMRI and Opioid Abstinence

Virtual Reality and Olfactory Stimuli Multimodal Intervention to Reduce Post-Operative Pain and Anxiety in Patients Undergoing Cardiothoracic Surgery

Massachusetts General Hospital

View Trial →

NCT05877157

Recruiting

Pain AND Opioids After Surgery

Enrollment

10,000 pts

Location

Croatia, United King...

Sponsor

University of Aberdeen

View Trial →

NCT04044820

Recruiting

Opioid Use Post-Discharge After Ambulatory Distal Arm Surgery

University Health Network, Tor...

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NCT06032559 Phase 3

Recruiting

Implementation and Effectiveness of Mindfulness Oriented Recovery Enhancement as an Adjunct to Methadone Treatment

Rutgers, The State University ...

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NCT06270147 Phase 2

Recruiting

Timing of TAP Blocks in Bariatric Surgery

SPSIP Block Versus ESP Block for Chronic Pain After Unilateral Breast Surgery

ESP Block Versus Wound Infiltration for Laminectomy

Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation

Johns Hopkins University

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NCT06084520

Recruiting

Translation and Validation of the COMM and ASI-SR

Related Conditions

pain postoperative (4) pain (2) postoperative pain (2) pain chronic (2) bone metastases (1) lymphoma (1) multiple myeloma (1) bariatric surgery candidate (1) nausea and vomiting postoperative (1) drug use disorder (1) opioid dependence (1) opioid related disorders (1)

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology