NCT07104825 Autonomic Neural Blockade in Bariatric Surgery
| NCT ID | NCT07104825 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Endeavor Health |
| Condition | Bariatric Surgery Candidate |
| Study Type | INTERVENTIONAL |
| Enrollment | 200 participants |
| Start Date | 2026-02-05 |
| Primary Completion | 2027-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 200 participants in total. It began in 2026-02-05 with a primary completion date of 2027-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this research is to evaluate if autonomic nerve block (ANB- blocking pain and nausea signals) decreases pain and anti-nausea medication requirements as well as the experience of pain/nausea during the first 72 hours after sleeve gastrectomy or gastric bypass surgery. Participants will be randomly assigned either to the standard of care or the ANB group before surgery. As part of standard of care, in both groups, laparoscopic bariatric surgery will be initiated with local anesthetic injected into the abdominal wall. In the ANB group, participants will be given an additional injection of local anesthetic medication to block nerves on and around the stomach.
Eligibility Criteria
Inclusion Criteria: * Individuals able and willing to consent and participate in all study activities * Adults, ages 18-90 * All patients with severe obesity undergoing laparoscopic/robotic gastric bypass or sleeve gastrectomy Exclusion Criteria: * Patients taking opiates chronically * Patients allergic to study medications * Patients with any prior adverse reaction to ingredients included in the block * Adults unable to consent * Pregnant women * Prisoners
Contact & Investigator
Herbert Hedberg, MD
PRINCIPAL INVESTIGATOR
Endeavor Health
Frequently Asked Questions
Who can join the NCT07104825 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 90 Years, studying Bariatric Surgery Candidate. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07104825 currently recruiting?
Yes, NCT07104825 is actively recruiting participants. Contact the research team at herbert.hedberg@endeavorhealth.org for enrollment information.
Where is the NCT07104825 trial being conducted?
This trial is being conducted at Evanston, United States.
Who is sponsoring the NCT07104825 clinical trial?
NCT07104825 is sponsored by Endeavor Health. The principal investigator is Herbert Hedberg, MD at Endeavor Health. The trial plans to enroll 200 participants.