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pain postoperative

Total Trials
8
Recruiting Now
8
Trial Phases
Phase 2, Phase 4

Pain clinical trials span acute procedural pain, chronic musculoskeletal pain, neuropathic pain, and cancer-related pain β€” each requiring distinct trial designs and patient-reported outcome instruments. The regulatory demand for non-opioid alternatives has intensified the search for novel analgesic mechanisms, particularly ion channel targets and neurostimulation approaches.

Active trials evaluate Nav1.7/1.8 blockers, CGRP antagonists for new indications, spinal cord stimulation refinements, virtual reality-based pain management, and patient-specific ketamine infusion protocols. Pain trials increasingly use ecological momentary assessment (EMA) diary approaches over traditional recall-based pain rating scales.

Frequently Asked Questions — pain postoperative Clinical Trials

How many clinical trials are currently recruiting for pain postoperative?
ClinicalMetric currently tracks 8 actively recruiting clinical trials for pain postoperative, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 8. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for pain postoperative?
pain postoperative research spans Phase 2 (2 trials), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a pain postoperative clinical trial?
Eligibility criteria for pain postoperative trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 2
2
Phase 4
1
Top Sponsors
Sindh Institute of Urology and Transplantation 1 trial
Centre de Médecine Intégrative et Complémentaire (CEMIC) 1 trial
Endeavor Health 1 trial
Washington University School of Medicine 1 trial
University of Aberdeen 1 trial

Recruiting Clinical Trials

NCT07512141
Recruiting
Single Versus Double Drains in the Axillary and Pectoral Regions After Modified Radical Mastectomy
Enrollment
60 pts
Location
Pakistan
Sponsor
Sindh Institute of Urology and...
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NCT06107595
Recruiting
Conditioned Open Label Placebo for Postoperative Pain Management
Enrollment
222 pts
Location
Switzerland
Sponsor
Centre de Médecine Intégrative...
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NCT07104825
Recruiting
Autonomic Neural Blockade in Bariatric Surgery
Enrollment
200 pts
Location
United States
Sponsor
Endeavor Health
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NCT07689162 Phase 2
Recruiting
Liposomal Bupivacaine vs Standard Bupivacaine for Post-Rhinoplasty Analgesia
Enrollment
45 pts
Location
United States
Sponsor
Washington University School o...
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NCT05877157
Recruiting
Pain AND Opioids After Surgery
Enrollment
10,000 pts
Location
Croatia, United King...
Sponsor
University of Aberdeen
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NCT06270147 Phase 2
Recruiting
Timing of TAP Blocks in Bariatric Surgery
Enrollment
100 pts
Location
Canada
Sponsor
McMaster University
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NCT05271331
Recruiting
ESP Block Versus Wound Infiltration for Laminectomy
Enrollment
112 pts
Location
Italy
Sponsor
University of Padova
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NCT03737292 Phase 4
Recruiting
Liposomal Bupivacaine Versus Plain Bupivacaine After Intercostal Injections For Pain Management After Thoracoscopy
Enrollment
40 pts
Location
United States
Sponsor
Milton S. Hershey Medical Cent...
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Related Conditions

opioid use (4) seroma following procedure (1) infections (1) bariatric surgery candidate (1) nausea and vomiting postoperative (1) pain chronic (1) quality of life (1) anesthesia local (1) surgery (1) pharmacokinetics (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology