| NCT ID | NCT05877157 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Aberdeen |
| Condition | Opioid Use |
| Study Type | OBSERVATIONAL |
| Enrollment | 10,000 participants |
| Start Date | 2023-09-25 |
| Primary Completion | 2026-05-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 10,000 participants in total. It began in 2023-09-25 with a primary completion date of 2026-05-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The aim of this study is to document the perioperative opioid use and its safety in the UK and countries in Europe and to describe its association with surgical complications, persistent pain and quality of life. In an international, prospective, observational cohort study, data about the perioperative pain management will be collected in all eligible hospitalised adult patients who undergo surgery in a designated "study week" in as many hospitals as possible in Europe. Baseline data will be collected, and participants followed up at one week, and at three and twelve months post-operatively. The primary outcome will be opioid use at three months after surgery. Secondary outcomes will include opioid use during the preoperative month (preoperative use), during surgery and up to one week after surgery (or discharge, whichever is earlier), and up to the end of the postoperative year. Additional secondary outcomes are the incidence of preoperative pain, persistent pain with/without the presence of neuropathic components, quality of life and surgical complications. The potential association between opioid use and pain outcomes will be investigated. This study could help to develop strategies to improve quality of care, through pain management, for patients undergoing surgery.
Eligibility Criteria
Inclusion Criteria: * hospitalised adult patients (18 years and older) undergoing any inpatient surgery (elective or emergency) during the designated study week where an anaesthetist is involved (general anaesthetic, sedation, local anaesthetic). Able to understand and has capacity to give written informed consent Exclusion Criteria: * American Society of Anaesthesiologists (ASA) grade V or VI * Refusal to participate. * Lack of comprehension of validated questionnaires or inability to complete the follow-up for any reason. * Lack of capacity to give written informed consent
Contact & Investigator
Patrice Forget
PRINCIPAL INVESTIGATOR
University of Aberdeen
Frequently Asked Questions
Who can join the NCT05877157 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Opioid Use. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05877157 currently recruiting?
Yes, NCT05877157 is actively recruiting participants. Contact the research team at patrice.forget@abdn.ac.uk for enrollment information.
Where is the NCT05877157 trial being conducted?
This trial is being conducted at Zagreb, Croatia, Aberdeen, United Kingdom, London, United Kingdom, Nottingham, United Kingdom.
Who is sponsoring the NCT05877157 clinical trial?
NCT05877157 is sponsored by University of Aberdeen. The principal investigator is Patrice Forget at University of Aberdeen. The trial plans to enroll 10,000 participants.