← Browse by Condition
Medical Condition

pain chronic

Total Trials
10
Recruiting Now
10
Trial Phases
Various

Pain clinical trials span acute procedural pain, chronic musculoskeletal pain, neuropathic pain, and cancer-related pain β€” each requiring distinct trial designs and patient-reported outcome instruments. The regulatory demand for non-opioid alternatives has intensified the search for novel analgesic mechanisms, particularly ion channel targets and neurostimulation approaches.

Active trials evaluate Nav1.7/1.8 blockers, CGRP antagonists for new indications, spinal cord stimulation refinements, virtual reality-based pain management, and patient-specific ketamine infusion protocols. Pain trials increasingly use ecological momentary assessment (EMA) diary approaches over traditional recall-based pain rating scales.

Frequently Asked Questions — pain chronic Clinical Trials

How many clinical trials are currently recruiting for pain chronic?
ClinicalMetric currently tracks 10 actively recruiting clinical trials for pain chronic, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 10. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for pain chronic?
pain chronic research spans multiple clinical trial phases. Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a pain chronic clinical trial?
Eligibility criteria for pain chronic trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Top Sponsors
University of Florida 1 trial
Palo Alto Veterans Institute for Research 1 trial
Sunnybrook Health Sciences Centre 1 trial
Cari Health Inc. 1 trial
University of Aberdeen 1 trial

Recruiting Clinical Trials

NCT06512727
Recruiting
The PROACTIVE Study for Black Elders
Enrollment
120 pts
Location
United States
Sponsor
University of Florida
View Trial →
NCT05700682
Recruiting
Perfusion MRI-targeted Joint Embolization for Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee
Enrollment
120 pts
Location
United States
Sponsor
Palo Alto Veterans Institute f...
View Trial →
NCT05865327
Recruiting
UltrasouNd-guided Percutaneous Intercostal Nerve Cryoneurolysis for Analgesia Following Traumatic Rib Fracture
Enrollment
24 pts
Location
Canada
Sponsor
Sunnybrook Health Sciences Cen...
View Trial →
NCT05981573
Recruiting
Assessment of Methadone Dose Taken
Enrollment
30 pts
Location
United States
Sponsor
Cari Health Inc.
View Trial →
NCT05877157
Recruiting
Pain AND Opioids After Surgery
Enrollment
10,000 pts
Location
Croatia, United King...
Sponsor
University of Aberdeen
View Trial →
NCT07325110
Recruiting
Interoceptive Awareness and Function in Adolescents With Chronic Pain
Enrollment
49 pts
Location
United States
Sponsor
Connecticut Children's Medical...
View Trial →
NCT07144033
Recruiting
Butyrate and Taurine for Chronic Postsurgical Pain in Adult Cardiac Surgical Patients
Enrollment
216 pts
Location
Hong Kong
Sponsor
Chinese University of Hong Kon...
View Trial →
NCT06541184
Recruiting
Ziconotide for Non-cancer Pain by Intrathecal Administration
Enrollment
85 pts
Location
France
Sponsor
ESTEVE Pharmaceuticals SAS
View Trial →
NCT06351839
Recruiting
Sleep Well Despite Persistent Pain Symptoms
Enrollment
106 pts
Location
Norway
Sponsor
University of Tromso
View Trial →
NCT06084520
Recruiting
Translation and Validation of the COMM and ASI-SR
Enrollment
400 pts
Location
Sweden
Sponsor
Uppsala University
View Trial →

Related Conditions

chronic pain (2) pain acute (2) opioid use (2) musculoskeletal pain (1) osteoarthritis (1) movement evoked pain (1) osteoarthritis knee (1) osteoarthritis hip (1) osteo arthritis shoulders (1) synovitis of knee (1) synovitis tenosynovitis hip (1) synovitis (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology