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Clinical Trials in Tennessee

Tennessee is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Tennessee and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.

Right now ClinicalMetric tracks 332 actively recruiting studies with Tennessee sites out of 332 registered in total. The busiest research areas in Tennessee are Solid Tumor, Breast Cancer, Acute Myeloid Leukemia. Leading sponsors running trials in the state include Vanderbilt University Medical Center, Merck Sharp & Dohme LLC, National Cancer Institute (NCI). By stage, Tennessee trials break down as Phase 1 (80), Phase 2 (113), Phase 3 (92), Phase 4 (14).

All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.

Total Trials
332
Recruiting Now
332
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Top Conditions in Tennessee
Solid Tumor (9)Breast Cancer (8)Acute Myeloid Leukemia (7)Ovarian Cancer (7)Endometrial Cancer (6)Advanced Solid Tumor (6)Metastatic Breast Cancer (6)Pancreatic Cancer (5)Obesity (5)Solid Tumor, Adult (5)Advanced Solid Tumors (5)Multiple Myeloma (5)

Frequently Asked Questions — Clinical Trials in Tennessee

How many clinical trials are currently recruiting in Tennessee?
ClinicalMetric currently tracks 332 actively recruiting clinical trials with at least one location in Tennessee. The total number of registered studies—including active but not currently enrolling trials—is 332. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Tennessee?
Tennessee hosts clinical trials across a broad range of medical conditions, including Solid Tumor, Breast Cancer, Acute Myeloid Leukemia, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Tennessee serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Tennessee?
To join a clinical trial in Tennessee, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Tennessee maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.

Recruiting Trials in Tennessee

NCT06833073 Phase 2
Recruiting
A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Ca...
Condition
Urinary Bladder Neoplasms
Enrollment
308 pts
Location
United States, Argentina, Australia
Sponsor
Merck Sharp & Dohme LLC
View Trial →
NCT07365241 Phase 3
Recruiting
A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous...
Condition
Small Cell Lung Cancer
Enrollment
531 pts
Location
United States, Austria, Belgium
Sponsor
AbbVie
View Trial →
NCT05780034 Phase 1
Recruiting
A Study of AC676 for the Treatment of Relapsed/Refractory B-Cell Malignancies
Condition
Relapsed/Refractory B-cell Malignancies
Enrollment
60 pts
Location
United States
Sponsor
Accutar Biotechnology Inc
View Trial →
NCT03866382 Phase 2
Recruiting
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) ...
Condition
Bladder Adenocarcinoma
Enrollment
314 pts
Location
United States, Puerto Rico
Sponsor
National Cancer Institute (NCI
View Trial →
NCT07599670 Phase 1, Phase 2
Recruiting
A Study to Assess the Safety and Effects of ABBV-1758 Following Subcutaneous or ...
Condition
Alzheimer's Disease
Enrollment
210 pts
Location
United States, China
Sponsor
AbbVie
View Trial →
NCT06026410 Phase 1
Recruiting
KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors
Condition
Solid Tumors With HRAS Alterations
Enrollment
300 pts
Location
United States, France, Germany
Sponsor
Kura Oncology, Inc.
View Trial →
NCT05919680 Phase 2
Recruiting
A Study of NST-6179 in Subjects With Intestinal Failure-Associated Liver Disease...
Condition
Intestinal Failure Associated Liver Disease
Enrollment
36 pts
Location
United States
Sponsor
NorthSea Therapeutics B.V.
View Trial →
Page 14 of 14 — 332 trials total
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology