State PA
Clinical Trials in Pennsylvania
Pennsylvania is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Pennsylvania and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 492 actively recruiting studies with Pennsylvania sites out of 492 registered in total. The busiest research areas in Pennsylvania are Breast Cancer, Acute Myeloid Leukemia, Prostate Cancer. Leading sponsors running trials in the state include University of Pennsylvania, University of Pittsburgh, National Cancer Institute (NCI). By stage, Pennsylvania trials break down as Phase 1 (84), Phase 2 (127), Phase 3 (96), Phase 4 (12).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Pennsylvania
Frequently Asked Questions — Clinical Trials in Pennsylvania
How many clinical trials are currently recruiting in Pennsylvania?
ClinicalMetric currently tracks 492 actively recruiting clinical trials with at least one location in Pennsylvania. The total number of registered studies—including active but not currently enrolling trials—is 492. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Pennsylvania?
Pennsylvania hosts clinical trials across a broad range of medical conditions, including Breast Cancer, Acute Myeloid Leukemia, Prostate Cancer, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Pennsylvania serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Pennsylvania?
To join a clinical trial in Pennsylvania, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Pennsylvania maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Pennsylvania
NCT05668923 N/A
Recruiting
Speech Signals in Stuttering
Condition
Stuttering, Childhood
Enrollment
600 pts
Location
United States
Sponsor
University of Pittsburgh
NCT07188090 Phase 2
Recruiting
Mozobil for Autologous Hematopoietic Stem Cell Transplantation
Condition
Multiple Myeloma
Enrollment
100 pts
Location
United States
Sponsor
Thomas Jefferson University
NCT06843213 N/A
Recruiting
Teaching Health Resilience in a Hospital Setting: A Peer-led Intervention
Condition
Opioid Use Disorder
Enrollment
390 pts
Location
United States
Sponsor
University of Pennsylvania
NCT05471908 N/A
Recruiting
Follow-up Automatically vs. As-Needed Comparison (FAAN-C) Trial
Condition
Pneumonia
Enrollment
2,674 pts
Location
United States
Sponsor
University of Utah
NCT06998940 Phase 3
Recruiting
Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Adva...
Condition
Locally Advanced Pancreatic Adenocarcinoma
Enrollment
94 pts
Location
United States
Sponsor
SWOG Cancer Research Network
NCT05699174 Phase 3
Recruiting
PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After F...
Condition
Infections
Enrollment
250 pts
Location
United States
Sponsor
Major Extremity Trauma Researc
NCT02780297 N/A
Recruiting
Prospective Research Rare Kidney Stones (ProRKS)
Condition
Hyperoxaluria
Enrollment
220 pts
Location
United States, Canada, Iceland
Sponsor
Mayo Clinic
NCT00327860 N/A
Recruiting
Chronic Kidney Disease in Children Prospective Cohort Study (CKiD)
Condition
Chronic Kidney Disease
Enrollment
1,300 pts
Location
United States
Sponsor
Johns Hopkins Bloomberg School
NCT05443126 Phase 1, Phase 2
Recruiting
A Study of EP0031 (Lunbotinib) in Patients With Advanced RET-altered Malignancie...
Condition
NSCLC
Enrollment
265 pts
Location
United States, France, Germany
Sponsor
Ellipses Pharma
NCT07049926 Phase 1, Phase 2
Recruiting
Substudy 03C: A Study of Combination Therapies in Participants With Renal Cell C...
Condition
Renal Cell Carcinoma
Enrollment
140 pts
Location
United States, Chile, France
Sponsor
Merck Sharp & Dohme LLC
NCT06780085 Phase 2
Recruiting
A Study of Investigational Agents in Participants With Previously Treated Stage ...
Condition
Carcinoma, Non-Small-Cell Lung
Enrollment
96 pts
Location
United States, Chile, Germany
Sponsor
Merck Sharp & Dohme LLC
NCT07013474 Phase 3
Recruiting
A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 W...
Condition
COVID-19 Infection
Enrollment
300 pts
Location
United States, Argentina, Belgium
Sponsor
Pfizer
NCT07290140 N/A
Recruiting
Paclitaxel-Coated Balloon Treatment of Chronic Rhinosinusitis
Condition
Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps
Enrollment
300 pts
Location
United States
Sponsor
Airiver Medical, Inc.
NCT06824168 Phase 2
Recruiting
Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acut...
Condition
Acute Myeloid Leukemia
Enrollment
130 pts
Location
United States, Australia, Brazil
Sponsor
Daiichi Sankyo
NCT06843590 Phase 2
Recruiting
A Study to Evaluate the Safety and Effectiveness of ALKS 2680 in Subjects With I...
Condition
Idiopathic Hypersomnia
Enrollment
126 pts
Location
United States, Australia, Belgium
Sponsor
Alkermes, Inc.
NCT05197920 N/A
Recruiting
Diabetes RElated to Acute Pancreatitis and Its Mechanisms
Condition
Acute Pancreatitis
Enrollment
800 pts
Location
United States
Sponsor
Milton S. Hershey Medical Cent
NCT07216391 Phase 2
Recruiting
Platform Trial to Delay Stage 3 Diabetes: Comparing Teplizumab With ATG
Condition
Type 1 Diabetes Mellitus
Enrollment
60 pts
Location
United States
Sponsor
National Institute of Diabetes
NCT06638554 N/A
Recruiting
Integrating Telehealth to Advance Lung Cancer Screening
Condition
Early Detection of Cancer
Enrollment
6,000 pts
Location
United States
Sponsor
Abramson Cancer Center at Penn
NCT01894802 N/A
Recruiting
Cortical Recording and Stimulating Array Brain-Machine Interface
Condition
Tetraplegia
Enrollment
30 pts
Location
United States
Sponsor
Michael Boninger
NCT07216703 Phase 3
Recruiting
A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembro...
Condition
Cervical Cancer
Enrollment
1,023 pts
Location
United States, Argentina, Austria
Sponsor
Merck Sharp & Dohme LLC
NCT07273422 N/A
Recruiting
Novel Self-charging, Medical-Grade Smart Insoles With AI/ML Edge Computing to Mo...
Condition
No Applicable Condition; Study of Physiologic Monitor Alarms
Enrollment
150 pts
Location
United States
Sponsor
Spectrum Ergonomics and Occupa
NCT07544979 N/A
Recruiting
Creation of a Decision Aid for Coronary Anomalies
Condition
AAOCA
Enrollment
60 pts
Location
United States
Sponsor
Vanderbilt University Medical
NCT06874322 N/A
Recruiting
Voiceitt for People With Impairments in Speech
Condition
Speech Impairment
Enrollment
20 pts
Location
United States
Sponsor
University of Pittsburgh
NCT02716246 Phase 2, Phase 3
Recruiting
Phase I/II/III Gene Transfer Clinical Trial of scAAV9.U1a.hSGSH
Condition
MPS IIIA
Enrollment
36 pts
Location
United States, Australia, Spain
Sponsor
Ultragenyx Pharmaceutical Inc
NCT07174310 Phase 3
Recruiting
A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in ...
Condition
Parkinson's Disease
Enrollment
900 pts
Location
United States, Australia, Austria
Sponsor
Hoffmann-La Roche
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology