State PA
Clinical Trials in Pennsylvania
Pennsylvania is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Pennsylvania and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 478 actively recruiting studies with Pennsylvania sites out of 478 registered in total. The busiest research areas in Pennsylvania are Prostate Cancer, Ovarian Cancer, Breast Cancer. Leading sponsors running trials in the state include University of Pennsylvania, University of Pittsburgh, Abramson Cancer Center at Penn Medicine. By stage, Pennsylvania trials break down as Phase 1 (82), Phase 2 (138), Phase 3 (101), Phase 4 (17).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Pennsylvania
Frequently Asked Questions — Clinical Trials in Pennsylvania
How many clinical trials are currently recruiting in Pennsylvania?
ClinicalMetric currently tracks 478 actively recruiting clinical trials with at least one location in Pennsylvania. The total number of registered studies—including active but not currently enrolling trials—is 478. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Pennsylvania?
Pennsylvania hosts clinical trials across a broad range of medical conditions, including Prostate Cancer, Ovarian Cancer, Breast Cancer, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Pennsylvania serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Pennsylvania?
To join a clinical trial in Pennsylvania, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Pennsylvania maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Pennsylvania
NCT06625385 N/A
Recruiting
A Study Evaluating the Safety and Efficacy of the 3M™ V.A.C. Peel and Place Dres...
Condition
Wound
Enrollment
90 pts
Location
United States
Sponsor
Solventum US LLC
NCT05299814 N/A
Recruiting
Impact of Parental Emotion Regulation on the Treatment of ADHD
Condition
ADHD
Enrollment
65 pts
Location
United States
Sponsor
Milton S. Hershey Medical Cent
NCT06551116 N/A
Recruiting
QuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 i...
Condition
HER2-positive Metastatic Breast Cancer
Enrollment
200 pts
Location
United States
Sponsor
Abramson Cancer Center at Penn
NCT03178149 Phase 1
Recruiting
A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losin...
Condition
Age-Related Macular Degeneration
Enrollment
42 pts
Location
United States
Sponsor
Astellas Institute for Regener
NCT04614103 Phase 2
Recruiting
Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer
Condition
Metastatic Non Small Cell Lung Cancer
Enrollment
170 pts
Location
United States, Australia, Canada
Sponsor
Iovance Biotherapeutics, Inc.
NCT04649242 Phase 3
Recruiting
Randomized Study in Children and Adolescents With Migraine: Acute Treatment
Condition
Pediatric Migraine
Enrollment
2,100 pts
Location
United States, Canada, China
Sponsor
Pfizer
NCT06270316 Phase 1, Phase 2
Recruiting
Safety, PK/PD, and Exploratory Efficacy Study of AMT-191 in Classic Fabry Diseas...
Condition
Fabry Disease
Enrollment
20 pts
Location
United States
Sponsor
UniQure Biopharma B.V.
NCT03217006 N/A
Recruiting
Randomization of Single vs Multiple Arterial Grafts
Condition
Coronary Artery Disease
Enrollment
4,300 pts
Location
United States, Austria, Brazil
Sponsor
Weill Medical College of Corne
NCT04181138 N/A
Recruiting
Primary Sclerosing Cholangitis in Children
Condition
Primary Sclerosing Cholangitis
Enrollment
1,000 pts
Location
United States, Canada
Sponsor
Arbor Research Collaborative f
NCT06430385 Phase 1, Phase 2
Recruiting
ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Phar...
Condition
Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome
Enrollment
48 pts
Location
United States, Austria, Canada
Sponsor
Ionis Pharmaceuticals, Inc.
NCT07082738 Phase 2
Recruiting
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Ve...
Condition
Chronic Obstructive Pulmonary Disease (COPD)
Enrollment
987 pts
Location
United States, Argentina, Australia
Sponsor
AstraZeneca
NCT05277558 N/A
Recruiting
Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Typ...
Condition
Type2 Diabetes
Enrollment
117 pts
Location
United States
Sponsor
Washington University School o
NCT06750094 Phase 3
Recruiting
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in P...
Condition
Colorectal Neoplasms
Enrollment
700 pts
Location
United States, Australia, Belgium
Sponsor
Janssen Research & Development
NCT04863222 Phase 4
Recruiting
Clinical and Radiographic Success of MTA vs Biodentine
Condition
Indirect Pulp Cap
Enrollment
646 pts
Location
United States
Sponsor
Geisinger Clinic
NCT05803941 Phase 4
Recruiting
Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With ...
Condition
Prostate Cancer
Enrollment
700 pts
Location
United States, Austria, Belgium
Sponsor
Novartis Pharmaceuticals
NCT03959800 N/A
Recruiting
Molecular Basis of Pediatric Liver Cancer
Condition
Childhood Liver Cancer
Enrollment
1,600 pts
Location
United States
Sponsor
University of Pittsburgh
NCT07047144 Phase 2
Recruiting
A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years ...
Condition
Spinal Muscular Atrophy
Enrollment
52 pts
Location
United States, Belgium, France
Sponsor
Scholar Rock, Inc.
NCT06772675 N/A
Recruiting
Vancomycin Reduction Practices (VRP) in the NICU
Condition
Antibiotic Stewardship
Enrollment
13 pts
Location
United States
Sponsor
Children's Hospital of Philade
NCT06809140 Phase 2
Recruiting
Enfortumab Vedotin Plus Pembrolizumab With Selective Bladder Sparing for Treatme...
Condition
Muscle Invasive Bladder Urothelial Carcinoma
Enrollment
75 pts
Location
United States
Sponsor
Matthew Galsky
NCT07028489 N/A
Recruiting
Prospective External Control Cohort In Patients With Newly Diagnosed Advanced or...
Condition
Non Small Cell Lung Cancer
Enrollment
130 pts
Location
United States
Sponsor
N-Power Medicine
NCT06252649 Phase 3
Recruiting
Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevac...
Condition
Metastatic Colorectal Cancer
Enrollment
450 pts
Location
United States, Argentina, Australia
Sponsor
Amgen
NCT05911568 N/A
Recruiting
Treatment With Endovascular Intervention for STroke Patients With Existing Disab...
Condition
Stroke
Enrollment
1,060 pts
Location
United States
Sponsor
University of Cincinnati
NCT07308873 N/A
Recruiting
Individual Differences in Gait and Osteoarthritis Pain
Condition
Knee Osteoarthritis (OA)
Enrollment
300 pts
Location
United States
Sponsor
University of Pittsburgh
NCT06957366 N/A
Recruiting
Perioperative Anticoagulant Use for Surgery Evaluation -2 (PAUSE-2) Study Patien...
Condition
Atrial Fibrillation (AF)
Enrollment
920 pts
Location
United States, Belgium, Canada
Sponsor
McMaster University
NCT07507422 N/A
Recruiting
Post Market Evaluation of Real World Outcomes and Durability to Support Implanta...
Condition
Chronic Pain
Enrollment
970 pts
Location
United States, Belgium, France
Sponsor
Medtronic
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology