State PA
Clinical Trials in Pennsylvania
Pennsylvania is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Pennsylvania and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 481 actively recruiting studies with Pennsylvania sites out of 481 registered in total. The busiest research areas in Pennsylvania are Breast Cancer, Acute Myeloid Leukemia, Ovarian Cancer. Leading sponsors running trials in the state include University of Pennsylvania, University of Pittsburgh, National Cancer Institute (NCI). By stage, Pennsylvania trials break down as Phase 1 (77), Phase 2 (124), Phase 3 (115), Phase 4 (15).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Pennsylvania
Frequently Asked Questions — Clinical Trials in Pennsylvania
How many clinical trials are currently recruiting in Pennsylvania?
ClinicalMetric currently tracks 481 actively recruiting clinical trials with at least one location in Pennsylvania. The total number of registered studies—including active but not currently enrolling trials—is 481. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Pennsylvania?
Pennsylvania hosts clinical trials across a broad range of medical conditions, including Breast Cancer, Acute Myeloid Leukemia, Ovarian Cancer, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Pennsylvania serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Pennsylvania?
To join a clinical trial in Pennsylvania, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Pennsylvania maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Pennsylvania
NCT07069673 N/A
Recruiting
Abbott Cephea Mitral Valve Disease Registry
Condition
Mitral Regurgitation
Enrollment
1,000 pts
Location
United States
Sponsor
Abbott Medical Devices
NCT06317662 Phase 2
Recruiting
Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer I...
Condition
Acute Leukemia of Ambiguous Lineage
Enrollment
153 pts
Location
United States, Puerto Rico
Sponsor
National Cancer Institute (NCI
NCT06441331 Phase 1
Recruiting
Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium L...
Condition
Somatostatin Receptor Positive
Enrollment
20 pts
Location
United States, France, Spain
Sponsor
ITM Solucin GmbH
NCT06844214 Phase 1, Phase 2
Recruiting
A Study to Investigate the Safety, Tolerability, and Efficacy of SAR446268, an A...
Condition
Myotonic Dystrophy
Enrollment
32 pts
Location
United States, Argentina, Australia
Sponsor
Sanofi
NCT06590467 N/A
Recruiting
Abbott Structural Heart Device Registry
Condition
Heart Diseases
Enrollment
2,500 pts
Location
United States, Denmark, Estonia
Sponsor
Abbott Medical Devices
NCT07417111 N/A
Recruiting
Continued Pressure for Alveolar Protection (CPAP Trial)
Condition
Bronchopulmonary Dysplasia (BPD)
Enrollment
860 pts
Location
United States
Sponsor
NICHD Neonatal Research Networ
NCT07023614 Phase 2
Recruiting
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Sy...
Condition
Non-obstructive Hypertrophic Cardiomyopathy
Enrollment
165 pts
Location
United States, Austria, Belgium
Sponsor
Imbria Pharmaceuticals, Inc.
NCT06003192 N/A
Recruiting
Screen Smart: Using Digital Health to Improve HIV Screening and Prevention
Condition
HIV Infections
Enrollment
63,000 pts
Location
United States
Sponsor
Children's Hospital Medical Ce
NCT06890598 Phase 3
Recruiting
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Particip...
Condition
Carcinoma, Non-Small-Cell Lung
Enrollment
700 pts
Location
United States, Australia, Austria
Sponsor
Eli Lilly and Company
NCT06400121 Phase 2
Recruiting
Apimostinel + Automated Neurocognitive Training for Depression
Condition
Depression
Enrollment
150 pts
Location
United States
Sponsor
Rebecca Price
NCT07167446 EARLY_Phase 1
Recruiting
Neuroprotective Potential of Cannabidiol (CBD) in Preventing Oxaliplatin (Ox)-In...
Condition
Oxaliplatin Induced Peripheral Neuropathy in Cancer Patients
Enrollment
30 pts
Location
United States
Sponsor
Fox Chase Cancer Center
NCT06904261 Phase 3
Recruiting
A Study of Migalastat in Pediatric Subjects (2 to <12 Yrs) With Fabry Disease an...
Condition
Fabry Disease
Enrollment
8 pts
Location
United States, Belgium, Germany
Sponsor
Amicus Therapeutics
NCT07015905 Phase 3
Recruiting
REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee ...
Condition
Venous Thromboembolism (VTE)
Enrollment
2,000 pts
Location
United States, Bulgaria, Hungary
Sponsor
Regeneron Pharmaceuticals
NCT03496636 N/A
Recruiting
Autologous Ovarian Tissue Transplantation
Condition
Female Infertility
Enrollment
5 pts
Location
United States
Sponsor
University of Pittsburgh
NCT05673499 N/A
Recruiting
International Study of Cerebral Oxygenation and Electrical Activity During Major...
Condition
Congenital Disorders
Enrollment
900 pts
Location
United States, Australia, Brazil
Sponsor
Children's Hospital of Philade
NCT07446296 N/A
Recruiting
Kidney Transplant Improvement Through New Exercise Training to Increase Capacity
Condition
Chronic Kidney Disease 5D
Enrollment
60 pts
Location
United States
Sponsor
University of Pennsylvania
NCT06283966 Phase 3
Recruiting
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fum...
Condition
COPD (Chronic Obstructive Pulmonary Disease)
Enrollment
5,250 pts
Location
United States, Argentina, Australia
Sponsor
AstraZeneca
NCT04743765 N/A
Recruiting
HIP Fracture Accelerated Surgical TreaTment And Care tracK 2 Trial
Condition
Hip Fractures
Enrollment
1,100 pts
Location
United States, Australia, Belgium
Sponsor
Population Health Research Ins
NCT06934967 Phase 3
Recruiting
Study to Assess the Pharmacokinetics, Safety, and Tolerability of Iptacopan in P...
Condition
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Enrollment
12 pts
Location
United States, Brazil, Colombia
Sponsor
Novartis Pharmaceuticals
NCT06876714 Phase 3
Recruiting
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People W...
Condition
Anatomic Stage I Breast Cancer AJCC v8
Enrollment
1,524 pts
Location
United States, Puerto Rico
Sponsor
Alliance for Clinical Trials i
NCT06582693 N/A
Recruiting
Refer2Quit: Evaluating a Proactive, Tailored, Population Health Approach for Tob...
Condition
Smoking
Enrollment
3,200 pts
Location
United States
Sponsor
Children's Hospital of Philade
NCT07630974 Phase 1, Phase 2
Recruiting
A Study of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refr...
Condition
Malignant Neoplasm
Enrollment
134 pts
Location
United States, Australia, Belgium
Sponsor
Merck Sharp & Dohme LLC
NCT04645862 N/A
Recruiting
Prospective 4D CTA of BAV Competence
Condition
Bicuspid
Enrollment
60 pts
Location
United States
Sponsor
University of Pennsylvania
NCT07132788 N/A
Recruiting
Understanding the Effects of Pulmonary Arterial Hypertension on Lean Muscle Mass
Condition
Pulmonary Hypertension
Enrollment
150 pts
Location
United States
Sponsor
University of Pennsylvania
NCT06450041 Phase 2
Recruiting
NANT 2021-01 Phase II STING (Sequential Temozolomide, Irinotecan, NK Cells and G...
Condition
Neuroblastoma
Enrollment
62 pts
Location
United States
Sponsor
New Approaches to Neuroblastom
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology