NCT07446296 Kidney Transplant Improvement Through New Exercise Training to Increase Capacity
| NCT ID | NCT07446296 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Pennsylvania |
| Condition | Chronic Kidney Disease 5D |
| Study Type | INTERVENTIONAL |
| Enrollment | 60 participants |
| Start Date | 2026-03-24 |
| Primary Completion | 2028-03 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 60 participants in total. It began in 2026-03-24 with a primary completion date of 2028-03.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to learn if a home-based exercise program can be safely and feasibly used to improve physical activity and physical function in adults waiting for a kidney transplant. The study will also learn how acceptable and useful this program is for participants. The main questions it aims to answer are: * Can a remote exercise program be delivered successfully to people on the kidney transplant waiting list? * Do participants follow the exercise program and wear a physical activity tracker as asked? * Is the program safe and well tolerated? Researchers will compare two groups to see if the exercise program leads to higher physical activity and better physical function: * Usual pre-transplant care with a physical activity tracker * Usual pre-transplant care plus an online exercise program Participants will: * Wear a wrist activity tracker to measure daily physical activity * Complete a one-week baseline period before being assigned to a study group * Be randomly assigned (like flipping a coin) to one of two groups * If assigned to the exercise group, take part in online exercise classes at home for 12 weeks with reminders and feedback, and then another 12 weeks without reminders and feedback * Answer questionnaires about their health, activity, and experience in the study This study may help researchers learn how to better support people waiting for kidney transplant through safe, home-based exercise programs.
Eligibility Criteria
Inclusion Criteria: * be at least 60 years old * receive transplant care at Penn Medicine * be on the kidney transplant waiting list * speak and comprehend English * be able to walk * have at least one physical function limitation OR at least one frailty metric * have access to a device capable of connecting to the Internet and downloading an application * be able to provide written informed consent * be cleared for participant via the Physical Activity Readiness Questionnaire (PARQ) verified against medical record or via written medical clearance from a clinician Exclusion Criteria: * Have had a myocardial infarction or a stroke in the 3 months immediately prior to enrollment * Be unable to self-monitor with study devices (i.e., have a condition such as dementia) * Not cleared by PARQ or receive written medical clearance to exercise * Participate in another physical activity study * Have any other reason they do not expect to be able to complete the study
Contact & Investigator
Sarah Schrauben, MD, MSCE
PRINCIPAL INVESTIGATOR
University of Pennsylvania
Frequently Asked Questions
Who can join the NCT07446296 clinical trial?
This trial is open to participants of all sexes, aged 60 Years or older, studying Chronic Kidney Disease 5D. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07446296 currently recruiting?
Yes, NCT07446296 is actively recruiting participants. Contact the research team at sarahsch@upenn.edu for enrollment information.
Where is the NCT07446296 trial being conducted?
This trial is being conducted at Philadelphia, United States.
Who is sponsoring the NCT07446296 clinical trial?
NCT07446296 is sponsored by University of Pennsylvania. The principal investigator is Sarah Schrauben, MD, MSCE at University of Pennsylvania. The trial plans to enroll 60 participants.
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