State PA
Clinical Trials in Pennsylvania
Pennsylvania is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Pennsylvania and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 481 actively recruiting studies with Pennsylvania sites out of 481 registered in total. The busiest research areas in Pennsylvania are Breast Cancer, Acute Myeloid Leukemia, Ovarian Cancer. Leading sponsors running trials in the state include University of Pennsylvania, University of Pittsburgh, National Cancer Institute (NCI). By stage, Pennsylvania trials break down as Phase 1 (77), Phase 2 (124), Phase 3 (115), Phase 4 (15).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Pennsylvania
Frequently Asked Questions — Clinical Trials in Pennsylvania
How many clinical trials are currently recruiting in Pennsylvania?
ClinicalMetric currently tracks 481 actively recruiting clinical trials with at least one location in Pennsylvania. The total number of registered studies—including active but not currently enrolling trials—is 481. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Pennsylvania?
Pennsylvania hosts clinical trials across a broad range of medical conditions, including Breast Cancer, Acute Myeloid Leukemia, Ovarian Cancer, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Pennsylvania serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Pennsylvania?
To join a clinical trial in Pennsylvania, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Pennsylvania maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Pennsylvania
NCT05204888 N/A
Recruiting
myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home
Condition
COPD
Enrollment
642 pts
Location
United States, Canada
Sponsor
Temple University
NCT07222982 N/A
Recruiting
Social Groups for Autistic Young Adults (SDARIYA)
Condition
Autism Spectrum Disorder
Enrollment
54 pts
Location
United States
Sponsor
Drexel University
NCT05836324 Phase 1
Recruiting
A Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Met...
Condition
Solid Tumors
Enrollment
570 pts
Location
United States, China, Denmark
Sponsor
Incyte Corporation
NCT07767903 Phase 3
Recruiting
A Trial of the Efficacy and Safety of a Fixed Dose of SEP-363856 in Adults With ...
Condition
Generalized Anxiety Disorder
Enrollment
384 pts
Location
United States
Sponsor
Otsuka Pharmaceutical Developm
NCT06496256 N/A
Recruiting
Barrigel® PPRT (Post-Prostatectomy Radiation Therapy) Trial
Condition
Prostate Cancer
Enrollment
84 pts
Location
United States, Australia
Sponsor
Palette Life Sciences, Inc.
NCT06370182 N/A
Recruiting
Safety and Effectiveness of Mechanical Thrombectomy Using the Anaconda ANA Funne...
Condition
Acute Ischemic Stroke From Large Vessel Occlusion
Enrollment
327 pts
Location
United States, France, Hungary
Sponsor
Anaconda Biomed S.L.
NCT07715188 N/A
Recruiting
Low Dose Radiotherapy for Osteoarthritis
Condition
Osteoarthitis
Enrollment
113 pts
Location
United States
Sponsor
Abramson Cancer Center at Penn
NCT05650229 Phase 2
Recruiting
Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease
Condition
Primary Mitochondrial Disease
Enrollment
180 pts
Location
United States, Australia, Belgium
Sponsor
Pharming Technologies B.V.
NCT07135583 N/A
Recruiting
Non-Invasive Interventions for Respiratory Recovery in Chronic Spinal Cord Injur...
Condition
Spinal Cord Injury, Chronic
Enrollment
20 pts
Location
United States
Sponsor
Thomas Jefferson University
NCT07455383 Phase 3
Recruiting
A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolep...
Condition
Narcolepsy Type 1
Enrollment
150 pts
Location
United States, Australia, Belgium
Sponsor
Alkermes, Inc.
NCT06022029 Phase 1
Recruiting
A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in ...
Condition
Triple Negative Breast Cancer
Enrollment
168 pts
Location
United States, Australia
Sponsor
OncoNano Medicine, Inc.
NCT06772623 Phase 1, Phase 2
Recruiting
Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab ...
Condition
Non Small Cell Lung Carcinoma
Enrollment
252 pts
Location
United States, Argentina, Australia
Sponsor
AbbVie
NCT04658303 N/A
Recruiting
Evolution of Metabolic and Immune Dysfunction in In-transit Melanoma
Condition
Melanoma
Enrollment
20 pts
Location
United States
Sponsor
Yana Najjar
NCT07441642 Phase 2
Recruiting
A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in Pa...
Condition
Geographic Atrophy Secondary to Age-related Macular Degeneration
Enrollment
272 pts
Location
United States, Argentina, Australia
Sponsor
Novartis Pharmaceuticals
NCT01276470 N/A
Recruiting
Environmental Risk Factors for the Anti-synthetase Syndrome
Condition
Myositis
Enrollment
580 pts
Location
United States
Sponsor
National Institute of Environm
NCT06062394 N/A
Recruiting
Penn Medicine Healthy Heart
Condition
Hypertension
Enrollment
1,980 pts
Location
United States
Sponsor
University of Pennsylvania
NCT06997588 Phase 2
Recruiting
EPIK-P4: A Phase II Single-arm Study to Assess the Efficacy, Safety and Pharmaco...
Condition
PIK3CA-related Overgrowth Spectrum (PROS)
Enrollment
140 pts
Location
United States, Australia, Austria
Sponsor
Novartis Pharmaceuticals
NCT07470853 Phase 1
Recruiting
A Study of MUC16-Directed Antibody Drug Conjugate HWK-016 in Participants With A...
Condition
PROC
Enrollment
265 pts
Location
United States
Sponsor
Whitehawk Therapeutics, Inc.
NCT06643741 N/A
Recruiting
Non-Invasive Preeclampsia Screening and Biobank
Condition
Preeclampsia (PE)
Enrollment
6,550 pts
Location
United States
Sponsor
Sequenom, Inc.
NCT05804188 N/A
Recruiting
CRICKET: Critical Events in Anaesthetised Kids Undergoing Tracheal Intubation
Condition
Intubation Complication
Enrollment
105,000 pts
Location
United States, Australia, Canada
Sponsor
Thomas Riva
NCT07631325 Phase 1, Phase 2
Recruiting
Axelopran and Nivolumab in PD-1-Refractory Metastatic Melanoma
Condition
Unresectable Cutaneous Melanoma
Enrollment
28 pts
Location
United States
Sponsor
John Kirkwood
NCT05763251 N/A
Recruiting
Comparison of Uncomplicated Candidemia Therapy Duration in Children and Adults
Condition
Invasive Candidiasis
Enrollment
420 pts
Location
United States, Australia
Sponsor
Arkansas Children's Hospital R
NCT06963463 N/A
Recruiting
Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents W...
Condition
Sleep Disturbance
Enrollment
90 pts
Location
United States
Sponsor
University of Pittsburgh
NCT06790693 Phase 3
Recruiting
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor a...
Condition
Breast Cancer
Enrollment
450 pts
Location
United States, Argentina, Australia
Sponsor
Hoffmann-La Roche
NCT06030063 N/A
Recruiting
The Society for Obstetric Anesthesia and Perinatology Research Network General A...
Condition
Cesarean Delivery
Enrollment
5,000 pts
Location
United States, Canada
Sponsor
Yale University
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology